Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Keishi Okubo"'
Autor:
Mihnea P. Dragomir, Enrique Fuentes-Mattei, Melanie Winkle, Keishi Okubo, Recep Bayraktar, Erik Knutsen, Aiham Qdaisat, Meng Chen, Yongfeng Li, Masayoshi Shimizu, Lan Pang, Kevin Liu, Xiuping Liu, Simone Anfossi, Huanyu Zhang, Ines Koch, Anh M. Tran, Swati Mohapatra, Anh Ton, Mecit Kaplan, Matthew W. Anderson, Spencer J. Rothfuss, Robert Silasi, Ravi S. Keshari, Manuela Ferracin, Cristina Ivan, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Constantin Georgescu, Pinaki P. Banerjee, Rafet Basar, Ziyi Li, David Horst, Catalin Vasilescu, Maria Teresa S. Bertilaccio, Katayoun Rezvani, Florea Lupu, Sai-Ching Yeung, George A. Calin
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 14 (2023)
Sepsis remains a leading cause of death for humans and currently has no pathogenesis-specific therapy. Hampered progress is partly due to a lack of insight into deep mechanistic processes. In the past decade, deciphering the functions of small noncod
Externí odkaz:
https://doaj.org/article/d4033ceefb364ffba4d3f09a718cc569
Autor:
Keishi Okubo, Takaaki Arigami, Daisuke Matsushita, Takashi Kijima, Masataka Shimonosono, Yoshikazu Uenosono, Shigehiro Yanagita, Hiroshi Kurahara, Shinichiro Mori, Takao Ohtsuka, Shoji Natsugoe
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Postoperative complications have been linked to the morbidity and mortality of several cancers. However, predicting whether complications will occur in the early period after surgery or not is challenging. Hence, this study aimed
Externí odkaz:
https://doaj.org/article/a9497e3729424b89832cdf6ba55cb3a7
Autor:
Takaaki Arigami, Daisuke Matsushita, Keishi Okubo, Takako Tanaka, Ken Sasaki, Masahiro Noda, Yoshiaki Kita, Shinichiro Mori, Yusuke Tsuruda, Hiroshi Kurahara, Takao Ohtsuka
Publikováno v:
Surgical Case Reports, Vol 6, Iss 1, Pp 1-5 (2020)
Abstract Background The prognosis of patients with recurrent gastric cancer is poor despite chemotherapy being clinically recommended as the first therapeutic strategy. Recent clinical trials have established the clinical utility of nivolumab in the
Externí odkaz:
https://doaj.org/article/d0a0365ff4e04393a3f1e53a279e068f
Autor:
Ryu Matsumoto, Takaaki Arigami, Daisuke Matsushita, Keishi Okubo, Takako Tanaka, Shigehiro Yanagita, Ken Sasaki, Masahiro Noda, Yoshiaki Kita, Shinichiro Mori, Hiroshi Kurahara, Takao Ohtsuka
Publikováno v:
World Journal of Surgical Oncology, Vol 18, Iss 1, Pp 1-6 (2020)
Abstract Background Patients with stage IV gastric cancer have a poor prognosis despite the recent development of multidisciplinary treatments that include chemotherapy. However, conversion surgery has emerged as a promising strategy to improve the p
Externí odkaz:
https://doaj.org/article/9ca9ef1bfcf74b84923615453e928b69
Autor:
Takako Tanaka, Takaaki Arigami, Yoshikazu Uenosono, Shigehiro Yanagita, Daisuke Matsushita, Keishi Okubo, Takashi Kijima, Yasuto Uchikado, Yoshiaki Kita, Shinichiro Mori, Ken Sasaki, Itaru Omoto, Hiroshi Kurahara, Kosei Maemura, Sumiya Ishigami, Shoji Natsugoe
Publikováno v:
Surgical Case Reports, Vol 6, Iss 1, Pp 1-6 (2020)
Abstract Background Patients with esophagogastric junction cancer are increasing in Western and Eastern countries. Conversely, the clinical significance of surgical resection remains controversial in these patients. We report a long-term survivor of
Externí odkaz:
https://doaj.org/article/7feb4e563bcb48859abc8208a53836a7
Autor:
Tetsushi Hirahara, Takaaki Arigami, Shigehiro Yanagita, Daisuke Matsushita, Yasuto Uchikado, Yoshiaki Kita, Shinichiro Mori, Ken Sasaki, Itaru Omoto, Hiroshi Kurahara, Kosei Maemura, Keishi Okubo, Yoshikazu Uenosono, Sumiya Ishigami, Shoji Natsugoe
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background The neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) are representative blood markers of systemic inflammatory responses. However, the clinical significance of the combination of these markers is unclear.
Externí odkaz:
https://doaj.org/article/9afdba4d7b80405f961ddd14a63608c2
Autor:
Katrien Van Roosbroeck, Recep Bayraktar, Steliana Calin, Johannes Bloehdorn, Mihnea Paul Dragomir, Keishi Okubo, Maria Teresa Sabrina Bertilaccio, Simonetta Zupo, M. James You, Gianluca Gaidano, Davide Rossi, Shih-Shih Chen, Nicholas Chiorazzi, Philip A. Thompson, Alessandra Ferrajoli, Francesco Bertoni, Stephan Stilgenbauer, Michael J. Keating, George A. Calin
Publikováno v:
Haematologica, Vol 104, Iss 5 (2019)
Richter syndrome is the name given to the transformation of the most frequent type of leukemia, chronic lymphocytic leukemia, into an aggressive lymphoma. Patients with Richter syndrome have limited response to therapies and dismal survival. The unde
Externí odkaz:
https://doaj.org/article/4a33e5992a2c4795ad8573264f7c5381
Autor:
Souichi Satake, Takaaki Arigami, Daisuke Matsushita, Keishi Okubo, Masataka Shimonosono, Ken Sasaki, Yusuke Tsuruda, Kan Tanabe, Shinichiro Mori, Shigehiro Yanagita, Yoshikazu Uenosono, Akihiro Nakajo, Hiroshi Kurahara, Takao Ohtsuka
Publikováno v:
Oncology. 101:12-21
Introduction: This study aimed to assess the clinical significance of eligibility criteria determined by phase 3 clinical trials in the clinical practice of patients with advanced gastric cancer who underwent chemotherapy. Methods: Patients with stag
Autor:
Takaaki Arigami, Daisuke Matsushita, Keishi Okubo, Masataka Shimonosono, Ken Sasaki, Yusuke Tsuruda, Yoshiaki Kita, Kan Tanabe, Shinichiro Mori, Shigehiro Yanagita, Yoshikazu Uenosono, Akihiro Nakajo, Hiroshi Kurahara, Takao Ohtsuka
Publikováno v:
Surgery Today. 52:1721-1730
Purpose To investigate the clinical indications and prognostic significance of surgical interventions after chemotherapy using trastuzumab-containing regimens for patients with human epidermal growth factor receptor 2 (HER2)-positive advanced gastric
Autor:
Ken Sasaki, Masahiro Noda, Yoshikazu Uenosono, Hiroshi Kurahara, Takao Ohtsuka, Sumiya Ishigami, Keishi Okubo, Yoshiaki Kita, Shinichiro Mori, Takaaki Arigami, Daisuke Matsushita, Shigehiro Yanagita
Publikováno v:
Surgery Today. 51:1851-1859
To assess the clinical indications for, and prognostic impact of surgery after, chemotherapy for type 4 gastric cancer. The subjects of this retrospective study were 67 patients who received chemotherapy for type 4 gastric cancer. The patients were g