Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Keisha M. Carr"'
Autor:
Colin A. Kretz, Shufang Gu, Andrew Yee, Keisha M. Carr, Beth McGee, Steven W. Pipe, Robert D. Gildersleeve, David Ginsburg
Publikováno v:
Blood. 124(3)
Plasma factor VIII (FVIII) and von Willebrand factor (VWF) circulate together as a complex. We identify VWF fragments sufficient for FVIII stabilization in vivo and show that hepatic expression of the VWF D'D3 domains (S764-P1247), either as a monome
Autor:
Austin N. Oleskie, Colin A. Kretz, Andrew Yee, Beth McGee, Robert D. Gildersleeve, Keisha M. Carr, David Ginsburg, Georgios Skiniotis, Min Su
Publikováno v:
Blood. 120:15-15
Abstract 15 Plasma factor VIII (fVIII) circulates in complex with von Willebrand factor (VWF) and is rapidly cleared in the absence of VWF. Previous in vitro studies have 1) localized the fVIII-binding region of VWF to the N-terminus, comprised of th