Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Keira Pereira"'
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Akademický článek
Cell surface profiling using high-throughput flow cytometry: a platform for biomarker discovery and analysis of cellular heterogeneity.
Autor: Craig A Gedye, Ali Hussain, Joshua Paterson, Alannah Smrke, Harleen Saini, Danylo Sirskyj, Keira Pereira, Nazleen Lobo, Jocelyn Stewart, Christopher Go, Jenny Ho, Mauricio Medrano, Elzbieta Hyatt, Julie Yuan, Stevan Lauriault, Mona Meyer, Maria Kondratyev, Twan van den Beucken, Michael Jewett, Peter Dirks, Cynthia J Guidos, Jayne Danska, Jean Wang, Bradly Wouters, Benjamin Neel, Robert Rottapel, Laurie E Ailles
Publikováno v: PLoS ONE, Vol 9, Iss 8, p e105602 (2014)
Cell surface proteins have a wide range of biological functions, and are often used as lineage-specific markers. Antibodies that recognize cell surface antigens are widely used as research tools, diagnostic markers, and even therapeutic agents. The a
Externí odkaz: https://doaj.org/article/26b8358f2d6c4080bcea0ab7bd509e76
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2
Proteomic Analysis of Cancer-Associated Fibroblasts Reveals a Paracrine Role for MFAP5 in Human Oral Tongue Squamous Cell Carcinoma
Autor: Thomas Kislinger, Ankit Sinha, W. Shi, Laurie Ailles, David P. Goldstein, Susie Su, Fei-Fei Liu, Simona Principe, Wei Xu, Alexandr Ignatchenko, Vladimir Ignatchenko, Salvador Mejia-Guerrero, Ilan Weinreb, Keira Pereira, Shao Hui Huang, Brian O'Sullivan
Publikováno v: Journal of Proteome Research. 17:2045-2059
Bidirectional communication between cells and their microenvironment is crucial for both normal tissue homeostasis and tumor growth. During the development of oral tongue squamous cell carcinoma (OTSCC), cancer-associated fibroblasts (CAFs) create a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b7ad882c7219b92df998d343ad3ad9
https://doi.org/10.1021/acs.jproteome.7b00925
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3
Cell surface profiling using high-throughput flow cytometry: a platform for biomarker discovery and analysis of cellular heterogeneity
Autor: Harleen Saini, Cynthia J. Guidos, Robert Rottapel, Jenny M. Ho, Mauricio Medrano, Jocelyn M. Stewart, Peter B. Dirks, Nazleen Lobo, Jayne S. Danska, Craig Gedye, Benjamin G. Neel, Julie Yuan, Danylo Sirskyj, Christopher Go, Ali Hussain, Maria Kondratyev, Twan van den Beucken, Laurie Ailles, Joshua Paterson, Stevan Lauriault, Bradly G. Wouters, Elzbieta Hyatt, Jean C.Y. Wang, Keira Pereira, Alannah Smrke, Michael A.S. Jewett
Publikováno v: PLoS ONE, Vol 9, Iss 8, p e105602 (2014)
PLOS ONE, 9(8):e105602. Public Library of Science
PLoS ONE
Cell surface proteins have a wide range of biological functions, and are often used as lineage-specific markers. Antibodies that recognize cell surface antigens are widely used as research tools, diagnostic markers, and even therapeutic agents. The a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198243ccbcd2a75cc170b4b9a635cd83
http://europepmc.org/articles/PMC4149490?pdf=render
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4
Abstract B08: Patient-derived xenografts of oral squamous cell carcinoma: A model system for the identification of prognostic molecular signatures and for preclinical assessment of targeted therapies
Autor: Jeff Bruce, Laurie Ailles, Keira Pereira, Christina Karamboulas, Jalna Meens, Trevor J. Pugh, Xin Qiu, Wei Xu, Shao Hui Huang, Ella Hyatt
Publikováno v: Clinical Cancer Research. 22:B08-B08
Patients treated for oral squamous cell carcinoma (OSCC) continue to have a poor overall survival rate. The existence of tumor heterogeneity produces major challenges to successfully treating OSCC. Patient-derived xenografts (PDXs) provide an importa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::57e3662299dcaddbf680444d1adda478
https://doi.org/10.1158/1557-3265.pdx16-b08
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5
Tumor-initiating cells are rare in many human tumors
Autor: Laurie Ailles, Zeshaan A. Rasheed, N. V. Rajeshkumar, Thomas K. Waddell, Erica K. Susky, Benjamin G. Neel, Christina Karamboulas, Keira Pereira, Nadeem Moghal, Kota Ishizawa, Jeanne Kowalski, Anirban Maitra, Robert Karisch, William Matsui, Manuel Hidalgo, Ming Tsao, Qiuju Wang
Publikováno v: Cell stem cell. 7(3)
SummaryTumor-initiating cells (TICs) are defined by their ability to form tumors after xenotransplantation in immunodeficient mice and appear to be relatively rare in most human cancers. Recent data in melanoma indicate that the frequency of TICs inc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a853a2e4b3334fc5e6fe35f03f3dce
https://pubmed.ncbi.nlm.nih.gov/20804964
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6
Abstract B34: Signaling in the tumor microenvironment: Proteomics analyses of stromal-tumor interaction in oral cancers
Autor: Alexander Ignatchenko, Laurie Ailles, Ankit Sinha, Thomas Kislinger, Vladimir Ignatchenko, Keira Pereira, Simona Principe
Publikováno v: Cancer Research. 75:B34-B34
Paracrine signaling between cancer-associated fibroblasts (CAFs) and cancer cells creates a bidirectional and cooperative network that drives cancer growth and progression. During the development of oral squamous cell carcinoma (OSCC), alterations in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::077e810b0a086b1d015eb9bf2851a4b2
https://doi.org/10.1158/1538-7445.chtme14-b34
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7
Co-Injection of patient-derived fibroblasts enhances tumor growth, stromal invasion, and epithelial-to-mesenchymal transition
Autor: Ines Lohse, Andrew Clayton Haller, David W. Hedley, Melania Pintilie, Stephen Chung, Amy Jackson-Fisher, Todd van Arsdale, Keira Pereira, Bradly G. Wouters, Catherine A. O’Brien, Christine Crossman, Laurie Ailles
Publikováno v: journal of Cancer Therapeutics and Research. 4:2
Tumor-stroma interactions are regulated through a network of autocrine and paracrine signaling pathways that are crucial for many aspects of tumor development. Activation and signaling through the HGF/Met pathway have been
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6fcc1edc9a82343ee7dc7b93dd0cf7d
https://doi.org/10.7243/2049-7962-4-2
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8
Abstract B47: Characterization of carcinoma-associated fibroblasts from head and neck squamous cell carcinoma
Autor: Joshua Paterson, Laurie Ailles, Keira Pereira, Elzbieta Hyatt, Christina Karamboulas
Publikováno v: Cancer Research. 73:B47-B47
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, with over 350,000 deaths annually. Metastasis remains a major cause of mortality for HNSCC patients. Elucidating the mechanisms leading to invasion and spread of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a1fa479b16547597d77e6c1bd27b9f2
https://doi.org/10.1158/1538-7445.fbcr13-b47
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