Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Keira Melican"'
Publikováno v:
Biofilm, Vol 8, Iss , Pp 100212- (2024)
Urinary tract infections (UTI) caused by uropathogenic Escherichia coli (UPEC) are a significant global health challenge. The UPEC biofilm lifestyle is believed to play an important role in infection recurrency and treatment resistance, but our under
Externí odkaz:
https://doaj.org/article/86ff34495b0b4f8aa6e3d48d3c3be3d8
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background An increasing number of patients are being prescribed anticoagulants and platelet inhibitors (antithrombotic treatment). Basic research has suggested an association between antithrombotic treatment and bacteremia during kidney inf
Externí odkaz:
https://doaj.org/article/c7c0badb7e14438d83f4fb43b7001202
Autor:
Valeria Manriquez, Pierre Nivoit, Tomas Urbina, Hebert Echenique-Rivera, Keira Melican, Marie-Paule Fernandez-Gerlinger, Patricia Flamant, Taliah Schmitt, Patrick Bruneval, Dorian Obino, Guillaume Duménil
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The human pathogen Neisseria meningitidis colonizes blood vessels and causes vascular damage, despite a neutrophil-rich inflammatory infiltrate. Here, Manriquez et al. use a humanized mouse model to show that pathogen colonization of capillaries and
Externí odkaz:
https://doaj.org/article/3831caa54fa047ecaa07a6a930b57045
Autor:
Ferdinand X. Choong, Smilla Huzell, Ming Rosenberg, Johannes A. Eckert, Madhu Nagaraj, Tianqi Zhang, Keira Melican, Daniel E. Otzen, Agneta Richter-Dahlfors
Publikováno v:
Biofilm, Vol 3, Iss , Pp 100060- (2021)
Biofilms enable bacteria to colonize numerous ecological niches. Bacteria within a biofilm are protected by the extracellular matrix (ECM), of which the fibril-forming amyloid protein curli and polysaccharide cellulose are major components in members
Externí odkaz:
https://doaj.org/article/5e440faa10c64f5190b12ef898a42788
Autor:
Svava E Steiner, Ferdinand X Choong, Haris Antypas, Carlos E Morado-Urbina, Anette Schulz, Alex Bersellini Farinotti, Duygu B Bas, Camilla I Svensson, Agneta Richter-Dahlfors, Keira Melican
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009553 (2021)
Bacterial infection results in a veritable cascade of host responses, both local and systemic. To study the initial stages of host-pathogen interaction in living tissue we use spatially-temporally controlled in vivo models. Using this approach, we sh
Externí odkaz:
https://doaj.org/article/7aa63820975e4aa19a92601a0e11356a
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
To successfully colonize a variety of environments, bacteria can coordinate complex collective behaviors such as biofilm formation. To thrive in oxygen limited niches, bacteria’s versatile physiology enables the utilization of alternative electron
Externí odkaz:
https://doaj.org/article/77c0618b160943c3b0d80e18e750998e
Autor:
Arthur Charles-Orszag, Feng-Ching Tsai, Daria Bonazzi, Valeria Manriquez, Martin Sachse, Adeline Mallet, Audrey Salles, Keira Melican, Ralitza Staneva, Aurélie Bertin, Corinne Millien, Sylvie Goussard, Pierre Lafaye, Spencer Shorte, Matthieu Piel, Jacomine Krijnse-Locker, Françoise Brochard-Wyart, Patricia Bassereau, Guillaume Duménil
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Meningococci remodel the plasma membrane of host cells during infection. Here, Charles-Orszag et al. show that plasma membrane remodeling occurs independently of F-actin, along meningococcal type IV pili fibers, by a physical mechanism that they term
Externí odkaz:
https://doaj.org/article/a3ee3d2a3841419284f54580f2ed54ad
Autor:
John Sedin, Antoine Giraud, Svava E. Steiner, David Ahl, A. Erik G. Persson, Keira Melican, Agneta Richter-Dahlfors, Mia Phillipson
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
We developed an experimental set up that enables longitudinal studies of immune cell behavior in situ in the challenged as well as unchallenged kidney of anesthetized mice over several hours. Using highly controlled vacuum to stabilize the kidney, th
Externí odkaz:
https://doaj.org/article/a8d9c80d6208414cb2da9793e6ff3497
Autor:
Anette Schulz, Long Jiang, Lisanne de Vor, Marcus Ehrström, Fredrik Wermeling, Liv Eidsmo, Keira Melican
Publikováno v:
Cell Reports, Vol 29, Iss 5, Pp 1074-1081.e5 (2019)
Summary: Staphylococcus aureus is a leading cause of skin and soft issue infection, but paradoxically, it also transiently, and often harmlessly, colonizes human skin. An obstacle to understanding this contradiction has been a shortage of in vivo mod
Externí odkaz:
https://doaj.org/article/bed1c0a845fc4ec8b22626a4f785fd53
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003139 (2013)
Septic shock caused by Neisseria meningitidis is typically rapidly evolving and often fatal despite antibiotic therapy. Further understanding of the mechanisms underlying the disease is necessary to reduce fatality rates. Postmortem samples from the
Externí odkaz:
https://doaj.org/article/6d0302ba2dc94fa3ac2b876651147aaf