Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Keinosuke Miyauchi"'
Autor:
Yuzo Kazuno, Michio Matsuhashi, Atsushi Tamura, Katsuyoshi Iwamatsu, Hitoshi Goi, Takahiro Ishii, Shigeharu Inouye, Keinosuke Miyauchi, Tsutomu Tsuruoka
Publikováno v:
The Journal of antibiotics. 37(11)
The effect of chemical modification of the D-amino acid function, which represents the C-7 beta substituent of cephamycin MT-141 on in vitro antibacterial activity was examined. MT-141 was more active on Gram-negative organisms than Gram-positive one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1304a20410a2f85e7595464ddcd21d
https://pubmed.ncbi.nlm.nih.gov/6439712
https://pubmed.ncbi.nlm.nih.gov/6439712
Autor:
Takashi Tsuruoka, Mizutani Kazuko, Tadahiro Watanabe, Hiroko Ogino, Shigeharu Inouye, Keinosuke Miyauchi, Katsuyoshi Iwamatsu, Taro Niida, Shoji Omoto
Publikováno v:
The Journal of antibiotics. 36(3)
C-7 and C-3 substituents of a new antibiotic SF-1623 were chemically modified to improve the bioactivity, and substituent effect at C-7 and C-3 was examined on the basis of MIC and ED50 values against selected bacteria. Among a large number of deriva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79cc6b94f7eecd0257455d9679dab1de
https://pubmed.ncbi.nlm.nih.gov/6833144
https://pubmed.ncbi.nlm.nih.gov/6833144
Autor:
Michio Matsuhashi, Aiko Miyata, Fumitoshi Ishino, Tsutomu Tsuruoka, Ynjiro Yamada, Aiko Hirata, Shigeharu Inouye, Keinosuke Miyauchi, Hitoshi Goi
Publikováno v:
The Journal of antimicrobial chemotherapy. 15(2)
MT-141, a new cephamycin (7 alpha-methoxy-cephalosporin) antibiotic with a D-cysteine moiety in its 7 beta-side chain, has binding affinities to penicillin-binding proteins of Escherichia coli and an inhibitory action on their transpeptidase activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc85222bb6b4b6508930032415eb0acd
https://pubmed.ncbi.nlm.nih.gov/3920178
https://pubmed.ncbi.nlm.nih.gov/3920178
Autor:
Shigeharu Inouye, Keinosuke Miyauchi, Tetsuro Hara, Takashi Yoshida, Yuzo Kazuno, Yoshinori Orikasa, Takeshi Nishino, Katsumi Kawaharajo, Fumiya Hirano, Hitoshi Goi, Hiroyuki Kadosawa, Tadahiro Watanabe
Publikováno v:
Antimicrobial Agents and Chemotherapy. 27:882-882
The in vitro and in vivo antibacterial activities of MT-141 were compared with those of cefoxitin, cefmetazole, moxalactam, cefotaxime, and cefoperazone. The MICs of MT-141 for 90% of bacterial isolates were lower than the reference drugs against cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a3ddc2dda16c6f6327c1e8d1568f9d5
https://doi.org/10.1128/aac.27.5.882-a
https://doi.org/10.1128/aac.27.5.882-a