Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Keilly Kuykhoven"'
Autor:
Zhi Ling Teo, Mark J. O’Connor, Stephanie Versaci, Kylie A. Clarke, Emmaline R. Brown, Luke W. Percy, Keilly Kuykhoven, Christopher P. Mintoff, Peter Savas, Balaji Virassamy, Stephen J. Luen, Ann Byrne, Sneha Sant, Geoffrey J. Lindeman, Phillip K. Darcy, Sherene Loi
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-16 (2023)
Abstract Novel therapeutic strategies that can effectively combine with immunotherapies are needed in the treatment of triple-negative breast cancer (TNBC). We demonstrate that combined PARP and WEE1 inhibition are synergistic in controlling tumour g
Externí odkaz:
https://doaj.org/article/bce6df774b064a2787512a67c74201f2
Autor:
Andjelija Zivanovic Bujak, Chen-Fang Weng, Maria João Silva, Miriam Yeung, Louisa Lo, Sarah Ftouni, Cassandra Litchfield, Yi-An Ko, Keilly Kuykhoven, Courtney Van Geelen, Sushma Chandrashekar, Mark A Dawson, Sherene Loi, Stephen Q Wong, Sarah-Jane Dawson
Publikováno v:
PLoS Medicine, Vol 17, Iss 10, p e1003363 (2020)
BackgroundMetastatic breast cancer (mBC) is a heterogenous disease with increasing availability of targeted therapies as well as emerging genomic markers of therapeutic resistance, necessitating timely and accurate molecular characterization of disea
Externí odkaz:
https://doaj.org/article/400cac0c048b46efa33e37a54f2ee850
Autor:
Magnus Zethoven, Paul A. James, David L Goode, Pietro Procopio, Na Li, Jia-Min Pang, Stephen B. Fox, Keilly Kuykhoven, Lisa Devereux, G. Bruce Mann, Sherene Loi, Grant Lee, Carolyn Nickson, David J Byrne, Siobhan Hughes, Kylie L. Gorringe, Peter Savas, Ian G. Campbell, Jacquie Connaughton, Tim Semple, Kenji M Fujihara, Simone M Rowley, Tanjina Kader, Kenneth Elder, Hugo Saunders, Dane Cheasley
Publikováno v:
The Journal of Pathology. 248:243-252
Breast cancer (BC) diagnosed after a negative mammogram but prior to the next screening episode is termed an 'interval BC' (IBC). Understanding the molecular differences between IBC and screen-detected BCs (SDBC) could improve mammographic screening
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4e6ee0f2e9687ccdf6a396de03d283
https://doi.org/10.1002/path.5251
https://doi.org/10.1002/path.5251
Autor:
Courtney T van Geelen, Peter Savas, Sherene Loi, Prudence A. Francis, Sarah-Jane Dawson, Chen-Fang Weng, Yi-An Ko, Stephen J Luen, Andrew Fellowes, Roberto Salgado, Keilly Kuykhoven, Stephen B. Fox, Zhi Ling Teo, Franco Caramia
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 22, Iss 1, Pp 1-13 (2020)
Breast Cancer Research, Vol 22, Iss 1, Pp 1-13 (2020)
Background Metastatic breast cancer remains incurable. Next-generation sequencing (NGS) offers the ability to identify actionable genomic alterations in tumours which may then be matched with targeted therapies, but the implementation and utility of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9cad69262c7733028d1a3470f0512a
https://pubmed.ncbi.nlm.nih.gov/35841108
https://pubmed.ncbi.nlm.nih.gov/35841108
Autor:
Sarah Ftouni, Sarah-Jane Dawson, S. Chandrashekar, Miriam M. Yeung, Mark A. Dawson, Andjelija Zivanovic Bujak, Stephen Q. Wong, Chen-Fang Weng, Keilly Kuykhoven, L. Lo, A. Ko, C. van Geelen, Maria Joao Silva, Cassandra Litchfield, Sherene Loi
Publikováno v:
Annals of Oncology. 30:v30
Background The increasing availability of targeted agents for treatment of metastatic breast cancer (mBC) necessitates accurate and timely molecular characterisation of disease. As a minimally invasive test, circulating tumour DNA (ctDNA) is well pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22cc1aac2ee797b8f386db2e763ea738
https://doi.org/10.1093/annonc/mdz239.016
https://doi.org/10.1093/annonc/mdz239.016
Autor:
Peter Savas, Maria Joao Silva, Keilly Kuykhoven, Courtney VanGeelen, Miriam M. Yeung, Sarah-Jane Dawson, Prudence A. Francis, Stephen J Luen, Rodney J. Hicks, Chen-Fang Weng, Andjelija Zivanovic Bujak, Sarah Ftouni, Lironne Wein, Sherene Loi, Kate Moodie, Chee Khoon Lee
Publikováno v:
Journal of Clinical Oncology. 36:1055-1055
1055Background: Mutations of genes involved in the PI3K signalling pathway occur frequently in BC. We performed a phase II study of BYL719, a selective PI3Kα inhibitor, in BC to evaluate its effica...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c22e01cc7ad8ac7cc2181bf71995424
https://doi.org/10.1200/jco.2018.36.15_suppl.1055
https://doi.org/10.1200/jco.2018.36.15_suppl.1055