Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Keila N. Crespo-Llado"'
Autor:
Daniela Masi, Keila N. Crespo-Llado, Amanda K. Lukens, Roger C. Wiegand, Dyann F. Wirth, Ann Rowley, Jeremy R. Duvall, Richard W. Heidebrecht, Mark E. Fitzgerald, Michael Foley, Adelfa E. Serrano, Nobutaka Kato, Stuart L. Schreiber, Marion Mercier, Benito Munoz, Carol A. Mulrooney, Christina Scherer, Eamon Comer, Maurice D. Lee, Michelle Palmer, Giovanni Muncipinto, Jennifer A. Beaudoin
Publikováno v:
Journal of Medicinal Chemistry
Here, we describe medicinal chemistry that was accelerated by a diversity-oriented synthesis (DOS) pathway, and in vivo studies of our previously reported macrocyclic antimalarial agent that derived from the synthetic pathway. Structure–activity re
Autor:
Jose E. Guerrero-Bravo, Santiago Ferrer, Thomas O'Shea, Chris J. Janse, Noemi Magan, Keila N. Crespo-Llado, María Belén Jiménez-Díaz, Shahid M. Khan, Robert H. Barker, Jeffrey D. Klinger, Erin Tyndall, Ralph Mazitschek, Dyann F. Wirth, Amar Bir Singh Sidhu, Bradley I. Coleman, Vanesa Gomez, Jon Clardy, Manoj T. Duraisingh, Edmund Sybertz, Roger C. Wiegand, Cassandra Celatka, Iñigo Angulo-Barturen, Mark Bree, Sameer Urgaonkar, Mikaela Levine, Hanlan Liu, Mandy Cromwell, Adelfa E. Serrano, Ian Bathurst, Petros Papastogiannidis, Edward R. Lee, María Santos Martínez, Benito Munoz, Sergio Wittlin, Jing-wen Lin, Joseph F. Cortese, Renato Skerlj
Publikováno v:
Antimicrobial Agents and Chemotherapy, 55(6), 2612-2622
This study characterizes aminoindole molecules that are analogs of Genz-644442. Genz-644442 was identified as a hit in a screen of ∼70,000 compounds in the Broad Institute's small-molecule library and the ICCB-L compound collection at Harvard Medic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fbde66a506d81a8bd5720aa4a9d64d
https://doi.org/10.1128/aac.01714-10
https://doi.org/10.1128/aac.01714-10