Acellularization-induced changes in tensile properties are organ specific: an in-vitro mechanical and structural analysis of porcine soft tissues

Autor: Schleifenbaum, Stefan, Prietzel, Torsten, Aust, Gabriela, Boldt, Andreas, Fritsch, Sebastian, Keil, Isabel, Koch, Holger, Möbius, Robert, Scheidt, Holger A., Wagner, Martin F. X., Hammer, Niels

Publikováno v: PLoS ONE 11(3): e0151223 doi:10.1371/journal.pone.0151223

Introduction: Though xenogeneic acellular scaffolds are frequently used for surgical reconstruction, knowledge of their mechanical properties is lacking. This study compared the mechanical, histological and ultrastructural properties of various nativ

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Acellularization-Induced Changes in Tensile Properties Are Organ Specific - An In-Vitro Mechanical and Structural Analysis of Porcine Soft Tissues.

Autor: Schleifenbaum S; Department of Orthopedic, Trauma and Plastic Surgery, University of Leipzig, Germany., Prietzel T; Department of Orthopedic, Trauma and Plastic Surgery, University of Leipzig, Germany., Aust G; Department of Surgery, Research Laboratories, University of Leipzig, Germany., Boldt A; Institute of Clinical Immunology, University of Leipzig, Germany., Fritsch S; Institute of Materials Science and Engineering, Technische Universität Chemnitz, Chemnitz, Germany., Keil I; Institute of Materials Science and Engineering, Technische Universität Chemnitz, Chemnitz, Germany.; Institute of Anatomy, University of Leipzig, Leipzig, Germany., Koch H; Translational Centre for Regenerative Medicine (TRM), Leipzig, Germany., Möbius R; Institute of Anatomy, University of Leipzig, Leipzig, Germany., Scheidt HA; Institute for Medical Physics and Biophysics, University of Leipzig, Leipzig, Germany., Wagner MF; Institute of Materials Science and Engineering, Technische Universität Chemnitz, Chemnitz, Germany., Hammer N; Department of Anatomy, University of Otago, Dunedin, New Zealand.

Publikováno v: PloS one [PLoS One] 2016 Mar 09; Vol. 11 (3), pp. e0151223. Date of Electronic Publication: 2016 Mar 09 (Print Publication: 2016).