Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Keiko Tano"'
Autor:
Takuya Kuroda, Satoshi Yasuda, Shiori Tachi, Satoko Matsuyama, Shinji Kusakawa, Keiko Tano, Takumi Miura, Akifumi Matsuyama, Yoji Sato
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Human induced pluripotent stem cells (hiPSCs) generate all cell types in the body, but different lines can differ in their potential. Here, the authors determine that higher endogenous levels of SALL3 in hiPSCs lead to ectoderm differentiation bias a
Externí odkaz:
https://doaj.org/article/46ec5862781d440890248a463ec73ca6
Identification of Minimal p53 Promoter Region Regulated by MALAT1 in Human Lung Adenocarcinoma Cells
Autor:
Keiko Tano, Rena Onoguchi-Mizutani, Fouzia Yeasmin, Fumiaki Uchiumi, Yutaka Suzuki, Tetsushi Yada, Nobuyoshi Akimitsu
Publikováno v:
Frontiers in Genetics, Vol 8 (2018)
The MALAT1 long noncoding RNA is strongly linked to cancer progression. Here we report a MALAT1 function in repressing the promoter of p53 (TP53) tumor suppressor gene. p21 and FAS, well-known p53 targets, were upregulated by MALAT1 knockdown in A549
Externí odkaz:
https://doaj.org/article/3c6f5b54edad4865be937833a0ba4942
Autor:
Satoshi Yasuda, Shinji Kusakawa, Takuya Kuroda, Takumi Miura, Keiko Tano, Nozomi Takada, Satoko Matsuyama, Akifumi Matsuyama, Michiyo Nasu, Akihiro Umezawa, Takao Hayakawa, Hideki Tsutsumi, Yoji Sato
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205022 (2018)
Human induced pluripotent stem cells (hiPSCs) represent promising raw materials of human cell-based therapeutic products (hCTPs). As undifferentiated hiPSCs exhibit intrinsic tumorigenicity properties that enable them to form teratomas, hCTPs contain
Externí odkaz:
https://doaj.org/article/e05fc1f3ac01447fbc2ef9c5fa9e15af
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110496 (2014)
Innovative applications of cell therapy products (CTPs) derived from human pluripotent stem cells (hPSCs) in regenerative medicine are currently being developed. The presence of residual undifferentiated hPSCs in CTPs is a quality concern associated
Externí odkaz:
https://doaj.org/article/4d820d1f61f44c70aa811667db34a3b0
Autor:
Rena Mizutani, Ai Wakamatsu, Noriyuki Tanaka, Hiroshi Yoshida, Naobumi Tochigi, Yoshio Suzuki, Tadahiro Oonishi, Hidenori Tani, Keiko Tano, Kenichi Ijiri, Takao Isogai, Nobuyoshi Akimitsu
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34949 (2012)
Whole transcriptome analyses have revealed a large number of novel transcripts including long and short noncoding RNAs (ncRNAs). Currently, there is great interest in characterizing the functions of the different classes of ncRNAs and their relevance
Externí odkaz:
https://doaj.org/article/3d5ec45b53c24dba8b36a374580678af
Autor:
Daisuke Mizuguchi, Takeshi Yamamoto, Yasuhiro Omiya, Koji Endo, Keiko Tano, Misa Oya, Satoru Takano
Appropriate intervention and care in detecting cognitive impairment early are essential to effectively prevent the progression of cognitive deterioration. Diagnostic voice analysis is a noninvasive and inexpensive screening method that could be usefu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::508f4359df8b1643417a7283aa2f86f0
https://doi.org/10.21203/rs.3.rs-2906887/v1
https://doi.org/10.21203/rs.3.rs-2906887/v1
Autor:
Hiroyasu Goto, Yota Kobayashi, Hiroki Sato, Tsugumi Fukunaga, Keiko Tanoue, Aoi Yamashiro, Hidehito Matsubara, Naoki Oshima
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background A percutaneous kidney biopsy (PKB) allows nephrologists to make informed decisions for treating various kidney diseases; however, the risk of bleeding complications should be considered, given the vascularity of the kidney. Many s
Externí odkaz:
https://doaj.org/article/499aa4932fba4915a4aa36cc18d7a3ed
Autor:
Akifumi Matsuyama, Shiori Tachi, Takumi Miura, Shinji Kusakawa, Satoko Matsuyama, Satoshi Yasuda, Yoji Sato, Keiko Tano, Takuya Kuroda
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
Clinical applications of human induced pluripotent stem cells (hiPSCs) are expected, but hiPSC lines vary in their differentiation propensity. For efficient selection of hiPSC lines suitable for differentiation into desired cell lineages, here we ide
Autor:
Keiko Tano, Yoji Sato, Shinji Kusakawa, Satoshi Yasuda, Yoshiki Sawa, Takuya Kuroda, Shin Kawamata, Satoko Matsuyama
Publikováno v:
Regenerative Therapy
Human pluripotent stem cells (hPSCs), such as human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), are leading candidate cells as raw materials for cell therapy products, because of their capacity for pluripotent diff
Autor:
Akifumi Matsuyama, Hideki Tsutsumi, Takuya Kuroda, Satoko Matsuyama, Akihiro Umezawa, Shinji Kusakawa, Yoji Sato, Satoshi Yasuda, Takao Hayakawa, Michiyo Nasu, Takumi Miura, Nozomi Takada, Keiko Tano
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0205022 (2018)
PLoS ONE, Vol 13, Iss 10, p e0205022 (2018)
Human induced pluripotent stem cells (hiPSCs) represent promising raw materials of human cell-based therapeutic products (hCTPs). As undifferentiated hiPSCs exhibit intrinsic tumorigenicity properties that enable them to form teratomas, hCTPs contain