Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Keiko TOYAMA"'
The effect of fibroblast growth factor 2 on neovascular vessels depends on the stage of angiogenesis
Autor:
Yuki Hattori, Haruhiko Yamada, Hidetsugu Mori, Shinpei Oba, Kaito Yokota, Masatoshi Omi, Yuichi Yamamoto, Keiko Toyama, Masayuki Ohnaka, Kanji Takahashi, Hisanori Imai
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e39843- (2024)
Objective: The exact relationship between fibroblast growth factor 2 (FGF2) and choroidal neovascularization (CNV) remains unclear. In this study, using optical coherence tomography angiography (OCTA) and FGF2-tg mice which are transgenic mice with a
Externí odkaz:
https://doaj.org/article/443db9cccb914a34ae4d12c11e60041c
Autor:
Masatoshi Omi, Haruhiko Yamada, Hajime Takahashi, Hidetsugu Mori, Shimpei Oba, Yuki Hattori, Kaito Yokota, Keiko Toyama, Kanji Takahashi
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27160- (2024)
Objective: Retinal vein occlusion (RVO) can lead to visual impairment, but the development of collateral vessels can sometimes mitigate significant damage. This study aimed to investigate the relationship between collateral vessels and hypertension,
Externí odkaz:
https://doaj.org/article/ed91a1acbbd143a5832cfad5ed269f97
Autor:
Hisatsugu Koshimizu, Nao Hirata, Keizo Takao, Keiko Toyama, Takashi Ichinose, Shigeki Furuya, Tsuyoshi Miyakawa
Publikováno v:
Neuropsychopharmacology Reports, Vol 39, Iss 1, Pp 56-60 (2019)
Abstract Aim Tryptophan hydroxylase 2 (Tph2) is a rate‐limiting enzyme for the biosynthesis of 5‐hydroxytryptamine (5‐HT, serotonin). Previous studies have reported that C1473G polymorphism of the murine Tph2 gene leads to decreased 5‐HT leve
Externí odkaz:
https://doaj.org/article/f3616c673ba446a5ba6addc8d254552f
Autor:
Hajime Takahashi, Kazuki Nakagawa, Haruhiko Yamada, Hidetsugu Mori, Shimpei Oba, Keiko Toyama, Kanji Takahashi
Publikováno v:
Heliyon, Vol 7, Iss 1, Pp e05902- (2021)
Background: It is clinically recognized that collateral vessels can form after retinal vein occlusion (RVO) in some cases and these vessels can lead to spontaneous recovery of the pathological condition. In recent years, optical coherence tomography
Externí odkaz:
https://doaj.org/article/bc23701ac63e4bfda0d6852a1803add6
Publikováno v:
Heliyon, Vol 4, Iss 9, Pp e00822- (2018)
Purpose: To establish a new evaluation method to quantify residual ophthalmic viscosurgical device (OVD) volume and corneal endothelium adhesion properties for phacoemulsification surgery. Methods: We compared the performance of four OVDs (Viscoat®,
Externí odkaz:
https://doaj.org/article/94ae86ee1feb44dbbb8d1af2962ae5d2
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201958 (2018)
This study aimed to investigate the differences between images obtained by optical coherence tomography angiography (OCTA) with those from immunohistochemical labeling of laser-induced choroidal neovascularization (CNV) in a mouse model. CNV was indu
Externí odkaz:
https://doaj.org/article/bb7b9a1a9cad4267b868a903def3e2c8
Autor:
Jidong Cheng, Hiroko Morisaki, Naomi Sugimoto, Atsushi Dohi, Takuya Shintani, Erika Kimura, Keiko Toyama, Masahito Ikawa, Masaru Okabe, Itsuro Higuchi, Satoshi Matsuo, Yasuaki Kawai, Ichiro Hisatome, Takako Sugama, Edward W. Holmes, Takayuki Morisaki
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 1, Iss C, Pp 51-59 (2014)
Mutation of the AMP deaminase 1 (AMPD1) gene, the predominate AMPD gene expressed in skeletal muscle, is one of the most common inherited defects in the Caucasian population; 2–3% of individuals in this ethnic group are homozygous for defects in th
Externí odkaz:
https://doaj.org/article/c8b0addbbc524d32b277d0be8e311740
Autor:
Keizo Takao, Koichi Tanda, Kenji Nakamura, Jiro Kasahara, Kazuki Nakao, Motoya Katsuki, Kazuo Nakanishi, Nobuyuki Yamasaki, Keiko Toyama, Minami Adachi, Masahiro Umeda, Tsutomu Araki, Kohji Fukunaga, Hisatake Kondo, Hiroyuki Sakagami, Tsuyoshi Miyakawa
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9460 (2010)
Calcium-calmodulin dependent protein kinase IV (CaMKIV) is a protein kinase that activates the transcription factor CREB, the cyclic AMP-response element binding protein. CREB is a key transcription factor in synaptic plasticity and memory consolidat
Externí odkaz:
https://doaj.org/article/3a5493edcb304dc090b5a2d22dbefa96
Autor:
Naoki Matsuo, Nobuyuki Yamasaki, Koji Ohira, Keizo Takao, Keiko Toyama, Megumi Eguchi, Shun Yamaguchi, Tsuyoshi Miyakawa
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 3 (2009)
The alpha-isoform of calcium/calmodulin-dependent protein kinase II (α-CaMKII) is expressed abundantly in the forebrain and is considered to have an essential role in synaptic plasticity and cognitive function. Previously, we reported that mice hete
Externí odkaz:
https://doaj.org/article/0a26f74b9808495c805a677e936449f6
Autor:
Naoki Matsuo, Koichi Tanda, Kazuo Nakanishi, Nobuyuki Yamasaki, Keiko Toyama, Keizo Takao, Hiroshi Takeshima, Tsuyoshi Miyakawa
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 3 (2009)
Dynamic regulation of the intracellular Ca2+ concentration is crucial for various neuronal functions such as synaptic transmission and plasticity, and gene expression. Ryanodine receptors (RyRs) are a family of intracellular calcium release channels
Externí odkaz:
https://doaj.org/article/d574a5f2017c4221ab3ceaa0bf1306fe