Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Keiko Sugai"'
Publikováno v:
Spine Surgery and Related Research, Vol 8, Iss 1, Pp 22-28 (2024)
Spinal cord injury (SCI) is a devastating injury that causes permanent neurological dysfunction. To develop a new treatment strategy for SCI, a clinical trial of transplantation of human-induced pluripotent stem cell-derived neural precursor cells (N
Externí odkaz:
https://doaj.org/article/c0f8ccb63a7e425cab8b8aa69dc4bd53
Autor:
Hiroki Okawara, Syoichi Tashiro, Tomonori Sawada, Keiko Sugai, Kohei Matsubayashi, Michiyuki Kawakami, Satoshi Nori, Osahiko Tsuji, Narihito Nagoshi, Morio Matsumoto, Masaya Nakamura
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 2, Pp 427-432 (2022)
Body weight-supported treadmill training with the voluntary driven exoskeleton (VDE-BWSTT) has been shown to improve the gait function of patients with chronic spinal cord injury. However, little is known whether VDE-BWSTT can effectively improve the
Externí odkaz:
https://doaj.org/article/8286c939416942dbae974ef2a63071c5
Autor:
Keiko Sugai, Miho Sumida, Tomoko Shofuda, Ryo Yamaguchi, Takashi Tamura, Tsuneo Kohzuki, Takayuki Abe, Reo Shibata, Yasuhiro Kamata, Shuhei Ito, Toshiki Okubo, Osahiko Tsuji, Satoshi Nori, Narihito Nagoshi, Shinya Yamanaka, Shin Kawamata, Yonehiro Kanemura, Masaya Nakamura, Hideyuki Okano
Publikováno v:
Regenerative Therapy, Vol 18, Iss , Pp 321-333 (2021)
Introduction: Our group has conducted extensive basic and preclinical studies of the use of human induced pluripotent cell (iPSC)-derived neural stem/progenitor cell (hiPSC-NS/PC) grafts in models of spinal cord injury (SCI). Evidence from animal exp
Externí odkaz:
https://doaj.org/article/9f05cdb2333747c08a851704d26efa31
Autor:
Keiko Sugai, Osahiko Tsuji, Shoko Takahashi, Morio Matsumoto, Masaya Nakamura, Nobuyuki Fujita
Publikováno v:
Journal of Orthopaedic Surgery, Vol 29 (2021)
Purpose: Many people with chronic musculoskeletal pain (CMP) seek healthcare from conventional and complementary and alternative medicine. However, treatment/therapy is not always adequate, patients often change healthcare providers, and some patient
Externí odkaz:
https://doaj.org/article/668bf59bd8bf4514b9cb4a78cd8c826d
Autor:
Go Itakura, Masahiro Ozaki, Narihito Nagoshi, Soya Kawabata, Yuichiro Nishiyama, Keiko Sugai, Tsuyoshi Iida, Rei Kashiwagi, Toshiki Ookubo, Kaori Yastake, Kohei Matsubayashi, Jun Kohyama, Akio Iwanami, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Resolving the immunogenicity of cells derived from induced pluripotent stem cells (iPSCs) remains an important challenge for cell transplant strategies that use banked allogeneic cells. Thus, we evaluated the immunogenicity of mouse fetal ne
Externí odkaz:
https://doaj.org/article/e1f32ce635554257b3877f4bba6341ec
Autor:
Go Itakura, Soya Kawabata, Miki Ando, Yuichiro Nishiyama, Keiko Sugai, Masahiro Ozaki, Tsuyoshi Iida, Toshiki Ookubo, Kota Kojima, Rei Kashiwagi, Kaori Yasutake, Hiromitsu Nakauchi, Hiroyuki Miyoshi, Narihito Nagoshi, Jun Kohyama, Akio Iwanami, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
Publikováno v:
Stem Cell Reports, Vol 8, Iss 3, Pp 673-684 (2017)
Human induced pluripotent stem cells (iPSCs) are promising in regenerative medicine. However, the risks of teratoma formation and the overgrowth of the transplanted cells continue to be major hurdles that must be overcome. Here, we examined the effic
Externí odkaz:
https://doaj.org/article/668d828c99c0461a96ad761bc1e5fc40
Autor:
Masahiro Ozaki, Akio Iwanami, Narihito Nagoshi, Jun Kohyama, Go Itakura, Hiroki Iwai, Soraya Nishimura, Yuichiro Nishiyama, Soya Kawabata, Keiko Sugai, Tsuyoshi Iida, Kohei Matsubayashi, Miho Isoda, Rei Kashiwagi, Yoshiaki Toyama, Morio Matsumoto, Hideyuki Okano, Masaya Nakamura
Publikováno v:
Stem Cell Research, Vol 19, Iss , Pp 128-138 (2017)
To achieve the goal of a first-in-human trial for human induced pluripotent stem cell (hiPSC)-based transplantation for the treatment of various diseases, allogeneic human leukocyte antigen (HLA)-matched hiPSC cell banks represent a realistic tool fr
Externí odkaz:
https://doaj.org/article/da59fb96669e49b9b11bba585cf3a55f
Autor:
Toshiki Okubo, Akio Iwanami, Jun Kohyama, Go Itakura, Soya Kawabata, Yuichiro Nishiyama, Keiko Sugai, Masahiro Ozaki, Tsuyoshi Iida, Kohei Matsubayashi, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
Publikováno v:
Stem Cell Reports, Vol 7, Iss 4, Pp 649-663 (2016)
Neural stem/progenitor cells (NS/PCs) derived from human induced pluripotent stem cells (hiPSCs) are considered to be a promising cell source for cell-based interventions that target CNS disorders. We previously reported that transplanting certain hi
Externí odkaz:
https://doaj.org/article/13dce45e2cf3473eb94563d7a1471d27
Autor:
Soya Kawabata, Morito Takano, Yuko Numasawa-Kuroiwa, Go Itakura, Yoshiomi Kobayashi, Yuichiro Nishiyama, Keiko Sugai, Soraya Nishimura, Hiroki Iwai, Miho Isoda, Shinsuke Shibata, Jun Kohyama, Akio Iwanami, Yoshiaki Toyama, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
Publikováno v:
Stem Cell Reports, Vol 6, Iss 1, Pp 1-8 (2016)
Murine- and human-induced pluripotent stem cell-derived neural stem/progenitor cells (iPSC-NS/PCs) promote functional recovery following transplantation into the injured spinal cord in rodents and primates. Although remyelination of spared demyelinat
Externí odkaz:
https://doaj.org/article/be73a51b191f4beaadfeb4d25fe9762f
Publikováno v:
Journal of Orthopaedic Surgery, Vol 25 (2017)
Background: Previous epidemiological surveys conducted in Japan highlighted problems with conventional approaches to treating chronic musculoskeletal pain. On the basis of prior studies, we initiated the “longitudinal investigation of chronic muscu
Externí odkaz:
https://doaj.org/article/1f1501cb2af143449ec594ac81de6b94