Sck Interacts with KDR and Flt-1 via Its SH2 Domain

Autor: Katsuhide Igarashi, Tomoka Yamano, Toshio Isohara, Isao Uno, Keiko Shigeta

Publikováno v: Biochemical and Biophysical Research Communications. 251:77-82

Vascular endothelial growth factor (VEGF) is one of the major angiogenesis regulators. It binds to its tyrosine kinase receptors, KDR and Flt-1. However, little is known about their downstream signal transduction properties. We screened human brain c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b66e3acb878d5bfe62984600e337eb
https://doi.org/10.1006/bbrc.1998.9442

Complete sequencing and characterization of 21,243 full-length human cDNAs

Autor: Yoko Yoshikawa, Hiroyo Kodaira, Akio Sugiyama, Kaoru Saito, Nobuo Nomura, Tsutomu Fujiwara, Naoko Katsuta, Shogo Moriya, Mitsuo Sekine, Tomoyasu Sugiyama, Hisatsugu Yuuki, Bunsei Kawakami, Sachiko Okamoto, Junichi Yamamoto, Koji Watanabe, Satoshi Aotsuka, Tadashi Satoh, Takami Komatsu, Yoshihiro Ohmori, Takao Iwayanagi, Akihiro Senoh, Machiko Tanikawa, Yasuko Ikema, Tomoko Hotuta, Takahide Yokoi, Naokazu Sasaki, Ryotaro Irie, Tatsunari Nishi, Sakae Togiya, Hirokazu Wakebe, Tadashi Senba, Yoshihiro Goto, Hiroshi Matsunawa, Yuko Terashima, Hiroshi Kondo, Katsue Yamada, Tetsuji Otsuki, Yasuhiko Masuho, Misato Morinaga, Hiroshi Mizoguchi, Makoto Takemoto, Asako Takahashi-Fujii, Kumiko Kamihara, Kiyomi Nakagawa, Saori Noguchi, Osamu Suzuki, Miho Arita, Susumu Hiraoka, Yuko Shirai, Kyoka Matsumura, Takeshi Watanabe, Kumi Abe, Hiromi Inagaki, Hiroyuki Sato, Manabu Watanabe, Ken Ninomiya, Yoshiyuki Chiba, Yusuke Nakamura, Shoko Itakura, Hiroko Momiyama, Emiko Kikkawa, Yuri Kawai, Yoshiko Nomura, Yoshie Nakajima, Hisashi Kikuchi, Manabu Kimata, Noriko Satoh, Yukiko Takahashi, Shinichi Ishida, Toshio Ota, Sachiko Takami, Tetsushi Yada, Atsushi Oshima, Reiko Hara, Keiko Shigeta, Takeshi Hikiji, Tetsuo Nishikawa, Hiroyuki Tanai, Satoshi Nakagawa, Ayako Kawabata, Kiyoshi Fujimori, Tadashi Ishibashi, Yoshiko Kaku, Yutaka Suzuki, Keiichi Nagai, Kouichi Ozaki, Takae Mizuno, Susumu Watanabe, Katsuhiro Kanda, Kazuha Takeuchi, Tomo-o Tanase, Katsuhiko Murakami, Masahide Sasaki, Makoto Yosida, Yasuhito Fukuzumi, Takehiko Hosoiri, Tomoko Itoh, Toshikazu Shibahara, Masaya Obayashi, Megumi Komiyama, Sumiyo Takiguchi, Koji Hayashi, Osamu Ohara, Hiroyuki Tashiro, Kazuomi Sato, Hiroto Hara, Makoto Yamazaki, Naoko Kobatake, Toshihiro Tanaka, Akiko Shiratori, Sanae Sano, Takuma Kawakami, Koji Okumura, Yoshifumi Fujimori, Masaaki Yamazaki, Kenji Nagahari, Sumio Sugano, Kouichi Kimura, Junko Kusano, Yukio Ono, Hiroaki Sudo, Takahiro Nagase, Fukuyo Komai, Yuko Isono, Haretsugu Hishigaki, Junko Mizushima-Sugano, Masako Wagatsuma, Fumio Shimizu, Hiroshi Makita, Yuka Fujii, Tatsuo Ichihara, Yuhi Omura, Tomohiro Yasuda, Kenta Nakai, Keiichi Kanehori, Shizuko Ishii, Takushi Togashi, Rie Okitani, Hiromichi Yamashita, Katsuji Murakawa, Akira Tanigami, Ai Wakamatsu, Namiko Shiohata, Kaoru Musashino, Ayako Kumagai, Toshihide Ono, Motoji Watanabe, Hiroko Hata, Yoshitaka Nakamura, Takako Furuya, Masaaki Oyama, Takao Isogai, Nobuyuki Imose, Masanori Sugawara, Makiko Takahashi, Riu Yamashita, Maasa Hirao

Publikováno v: Nature genetics. 36(1)

As a base for human transcriptome and functional genomics, we created the "full-length long Japan" (FLJ) collection of sequenced human cDNAs. We determined the entire sequence of 21,243 selected clones and found that 14,490 cDNAs (10,897 clusters) we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1423d4e4322c993cbee2219dafdff70a
https://pubmed.ncbi.nlm.nih.gov/14702039

Tyrosine 1213 of Flt-1 is a major binding site of Nck and SHP-2

Autor: Katsuhide Igarashi, Tomoka Yamano, Isao Uno, Toshiaki Kato, Keiko Shigeta, Toshio Isohara

Publikováno v: Biochemical and biophysical research communications. 246(1)

Vascular endothelial growth factor (VEGF) binds to its receptor tyrosine kinase Flt-1 and KDR/Flk-1 and stimulates their autophosphorylation. However, little is known about their downstream signal transduction properties. We examined the interactions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d639d9e5158552291c97baad2122cee6
https://pubmed.ncbi.nlm.nih.gov/9600074