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pro vyhledávání: '"Keiko Saisho"'
Autor:
Katherine C M Chew, Noriyuki Matsuda, Keiko Saisho, Grace G Y Lim, Chou Chai, Hui-Mei Tan, Keiji Tanaka, Kah-Leong Lim
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19720 (2011)
Mutations in the parkin gene, which encodes a ubiquitin ligase (E3), are a major cause of autosomal recessive parkinsonism. Although parkin-mediated ubiquitination was initially linked to protein degradation, accumulating evidence suggests that the e
Externí odkaz:
https://doaj.org/article/4987a5e223204bd09706a72f5e91c936
Autor:
Masaaki Komatsu, Shigeto Sato, Keiko Saisho, Yu-shin Sou, Mayumi Kimura, Kei Okatsu, Noriyuki Matsuda, Midori Shimanuki, Hiroshi Shitara, Nobutaka Hattori, Kazuto Nakada, Keiji Tanaka
Publikováno v:
Genes to Cells.
PINK1 and Parkin were first identified as the causal genes responsible for familial forms of early-onset Parkinson’s disease (PD), a prevalent neurodegenerative disorder. PINK1 encodes a mitochondrial serine/threonine protein kinase, whereas Parkin
Autor:
Sumihiro Kawajiri, Kei Okatsu, Masaaki Komatsu, Shigeto Sato, Keiko Saisho, Shinji Saiki, Nobutaka Hattori, Fumiaki Sato, Yu-shin Sou, Mayumi Kimura, Kahori Shiba, Keiji Tanaka, Noriyuki Matsuda, Clement A. Gautier
Publikováno v:
The Journal of Cell Biology
Defective mitochondrial quality control is shown to be a mechanism for neurodegeneration in some forms of Parkinson's disease.
Parkinson's disease (PD) is a prevalent neurodegenerative disorder. Recent identification of genes linked to familial
Parkinson's disease (PD) is a prevalent neurodegenerative disorder. Recent identification of genes linked to familial
Autor:
Keiko Saisho, Kah-Leong Lim, Hui-Mei Tan, Noriyuki Matsuda, Keiji Tanaka, Katherine C. M. Chew, Grace G. Y. Lim, Chou Chai
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19720 (2011)
PLoS ONE
PLoS ONE
Background Mutations in the parkin gene, which encodes a ubiquitin ligase (E3), are a major cause of autosomal recessive parkinsonism. Although parkin-mediated ubiquitination was initially linked to protein degradation, accumulating evidence suggests