Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Keiko Oshima"'
Autor:
Ryotaku Inoue, Keiko Oshima, Shin-ichi Inaba, Takashi Kagari, Kaoru Tanaka-takanaka, Wataru Tomisato, Takaichi Shimozato, Takashi Izumi, Hiromi Doi-Komuro, Maki Goto, Hiroshi Yuita, Hisako Tanaka
Publikováno v:
Biopharmaceutics & Drug Disposition. 37:561-573
The pharmacokinetic (PK) and pharmacodynamic (PD) modeling was conducted for the reduction of peripheral lymphocytes after oral administration of CS-0777 to healthy rats, monkeys and experimental autoimmune encephalomyelitis (EAE) induced rats. M1, t
Autor:
Shin-Ichi, Inaba, Maki, Goto, Kaoru, Tanaka-Takanaka, Hisako, Tanaka, Wataru, Tomisato, Hiroshi, Yuita, Hiromi, Doi-Komuro, Ryotaku, Inoue, Keiko, Oshima, Takashi, Kagari, Takaichi, Shimozato, Takashi, Izumi
Publikováno v:
Biopharmaceuticsdrug disposition. 37(9)
Pharmacokinetic (PK) and pharmacodynamic (PD) modeling was conducted for the reduction of peripheral lymphocytes after oral administration of CS-0777 to healthy rats, monkeys and experimental autoimmune encephalomyelitis (EAE) induced rats. The phosp
Autor:
Wataru Tomisato, Keisuke Suzuki, Ryotaku Inoue, Yumi Kawase, Takashi Izumi, Keiko Oshima, Hiroshi Yuita, Takaichi Shimozato, Katsuyoshi Nakajima, Takahide Nishi, Shojiro Miyazaki, Futoshi Nara, Yukiko Iio, Takashi Kagari, Shin-ichi Inaba, Takashi Ohnuki, Toshiyasu Takemoto, Hiromi Doi
Publikováno v:
ACS Medicinal Chemistry Letters. 2:368-372
CS-0777 (3) is phosphorylated in vivo, and the phosphate of CS-0777 (CS-0777-P) (4) acts as a selective S1P receptor-1 (S1P1) modulator. We report herein the synthesis of CS-0777 and CS-0777-P, pharmacological effects such as S1P1 and S1P3 agonist ac
Publikováno v:
Journal of JSEE. 66:5_88-5_93