Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Keiko Nohara"'
Publikováno v:
Environmental Health and Preventive Medicine, Vol 28, Pp 43-43 (2023)
Background: Arsenic is a harmful heavy metal and a well-known developmental neurotoxicant. Previously, we have reported that gestational arsenic exposure resulted in impaired social behaviors in F1 and F2 male mice. However, little is known about the
Externí odkaz:
https://doaj.org/article/72def14fde9c4b9f86c5a6dbe704474f
Publikováno v:
Environmental Health and Preventive Medicine, Vol 26, Iss 1, Pp 1-10 (2021)
Abstract Background Arsenic is a developmental neurotoxicant. It means that its neurotoxic effect could occur in offspring by maternal arsenic exposure. Our previous study showed that developmental arsenic exposure impaired social behavior and seroto
Externí odkaz:
https://doaj.org/article/6cc4da5eca954d39b79c14074b31390d
Autor:
Keiko Nohara, Kazuhiko Nakabayashi, Kazuyuki Okamura, Takehiro Suzuki, Shigekatsu Suzuki, Kenichiro Hata
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Background Environmental impacts on a fetus can disrupt germ cell development leading to epimutations in mature germ cells. Paternal inheritance of adverse health effects through sperm epigenomes, including DNA methylomes, has been recognize
Externí odkaz:
https://doaj.org/article/24fb8a1b3bd344ec84bcf0068e3ace63
Publikováno v:
Environmental Health and Preventive Medicine, Vol 25, Iss 1, Pp 1-12 (2020)
Abstract Background Various treatments for hepatocellular carcinoma (HCC) are utilized in clinical practice; however, the prognosis is still poor on account of high recurrence rates. DNA methylation levels of CpG islands around promoters (promoter Cp
Externí odkaz:
https://doaj.org/article/a975e88659fd47a69b74d1409b6fa207
Autor:
Mayumi Ohtsu, Nathan Mise, Akihiko Ikegami, Atsuko Mizuno, Yayoi Kobayashi, Yoshihiko Nakagi, Keiko Nohara, Takahiko Yoshida, Fujio Kayama
Publikováno v:
Environmental Health and Preventive Medicine, Vol 24, Iss 1, Pp 1-10 (2019)
Abstract Background Lead is a toxic metal abundant in the environment. Consumption of food contaminated at low levels of lead, especially by small children and pregnant women, raises a health concern. Methods Duplicated food portions and drinking wat
Externí odkaz:
https://doaj.org/article/96e7c156318045f895df91be9a6adf08
Autor:
Junya Matsushita, Kazuyuki Okamura, Kazuhiko Nakabayashi, Takehiro Suzuki, Yu Horibe, Tomoko Kawai, Toshihiro Sakurai, Satoshi Yamashita, Yoshikazu Higami, Gaku Ichihara, Kenichiro Hata, Keiko Nohara
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
Abstract Background C3H mice have been frequently used in cancer studies as animal models of spontaneous liver tumors and chemically induced hepatocellular carcinoma (HCC). Epigenetic modifications, including DNA methylation, are among pivotal contro
Externí odkaz:
https://doaj.org/article/783ed7f10a014020a38edc91abe20722
Publikováno v:
Toxicology and applied pharmacology. 454
Exposure to inorganic arsenic has been known to induce cancers in various organs, however, the underlying mechanisms remain unclear. Premature senescence refers to the irreversible growth arrest induced by stress stimuli. The senescence-associated se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582227359fe53e409697f5d2980df273
https://pubmed.ncbi.nlm.nih.gov/36089002
https://pubmed.ncbi.nlm.nih.gov/36089002
Publikováno v:
Current Topics in Environmental Health and Preventive Medicine ISBN: 9789811662485
The development of industry enriches people’s lives, yet on the other hand, it can cause serious disasters if not properly managed. From the early 1900s, Japan experienced several major pollution incidents due to severe environmental disruption by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25c4712ec1ce2cdd123b80eff5ca35d4
https://doi.org/10.1007/978-981-16-6249-2_7
https://doi.org/10.1007/978-981-16-6249-2_7
Autor:
Takehiro Suzuki, Kazuyuki Okamura, Kazuhiko Nakabayashi, Keiko Nohara, Tomoko Kawai, Tomoharu Sano, Kenichiro Hata
Publikováno v:
Cancer Science
Multigenerational adverse effects from the environment such as nutrition and chemicals are among important concerns in environmental health issues. Previously, we have found that arsenite exposure of only F0 females during their pregnancy increases h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd567992a541d1b2a0a10c1ae3a4355
http://europepmc.org/articles/PMC6676110
http://europepmc.org/articles/PMC6676110
Publikováno v:
Toxicology and applied pharmacology. 409
A growing body of evidence has shown that gestational exposure to environmental factors such as imbalanced diet, environmental chemicals, and stress can lead to late-onset health effects in offspring and that some of these effects are heritable by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda12ccf4300abe503a5ef6beed291cd
https://pubmed.ncbi.nlm.nih.gov/33160984
https://pubmed.ncbi.nlm.nih.gov/33160984