Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Keiko Miyoshi"'
Autor:
Motoharu Sarubo, Yasuhiro Mouri, Akira Moromizato, Azusa Yamada, Shengjan Jin, Wenhua Shao, Hiroko Hagita, Keiko Miyoshi, Yasusei Kudo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Head and neck squamous cell carcinoma (HNSCC) is a significant healthcare burden globally. Previous research using single-cell transcriptome analysis identified TGFBI as a crucial marker for the partial-epithelial-mesenchymal transition (par
Externí odkaz:
https://doaj.org/article/c88d1ee100cd40d4b66fe70630dc971e
Autor:
Shengjian Jin, Takaaki Tsunematsu, Taigo Horiguchi, Yasuhiro Mouri, Wenhua Shao, Keiko Miyoshi, Hiroko Hagita, Motoharu Sarubo, Natsumi Fujiwara, Guangying Qi, Naozumi Ishimaru, Yasusei Kudo
Publikováno v:
Cancer Medicine, Vol 12, Iss 24, Pp 22156-22169 (2023)
Abstract Background Comprehending the molecular mechanisms underlying head and neck squamous cell carcinoma (HNSCC) is vital for the development of effective treatment strategies. Deubiquitinating enzymes (DUBs), which regulate ubiquitin‐dependent
Externí odkaz:
https://doaj.org/article/b8b785699a9a4837967dc25a36773d99
Redefining GBA gene structure unveils the ability of Cap-independent, IRES-dependent gene regulation
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
The cell type-specific expression of the glucocerebrosidase gene, associated with the lysosomal storage disorder called Gaucher disease, is linked to cis- and trans-regulatory transcriptional and translational mechanisms.
Externí odkaz:
https://doaj.org/article/1513a9ca36b84fb28407adbc1675daa8
Autor:
Naoya Kawakita, Hiroaki Toba, Keiko Miyoshi, Shinichi Sakamoto, Daisuke Matsumoto, Mika Takashima, Mariko Aoyama, Seiya Inoue, Masami Morimoto, Takeshi Nishino, Hiromitsu Takizawa, Akira Tangoku
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-14 (2020)
Abstract Background Bronchioalveolar stem cells (BASCs) located at the bronchioalveolar-duct junction (BADJ) are stem cells residing in alveoli and terminal bronchioles that can self-renew and differentiate into alveolar type (AT)-1 cells, AT-2 cells
Externí odkaz:
https://doaj.org/article/fb26d0d5248147419835f82049b99ded
Autor:
Intan Ruspita, Pragnya Das, Yan Xia, Sarah Kelangi, Keiko Miyoshi, Takafumi Noma, Malcolm L. Snead, Rena N. D’Souza, Marianna Bei
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
BackgroundAmeloblasts are epithelially derived cells responsible for enamel formation through a process known as amelogenesis. Amongst the several transcription factors that are expressed during amelogenesis, both Msx2 and Sp6 transcription factors p
Externí odkaz:
https://doaj.org/article/00e9e2e83d584709bdd0b3c7738bdae9
Autor:
Ayako Tanimura, Keiko Miyoshi, Taigo Horiguchi, Hiroko Hagita, Koichi Fujisawa, Takafumi Noma
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 5, Pp 1936-1950 (2018)
Background/Aims: Endoplasmic reticulum (ER) stress and unfolded protein response (UPR) are involved in hematopoietic differentiation. However, the mechanistic linkage between ER stress/UPR and hematopoietic differentiation remains unclear. Methods: W
Externí odkaz:
https://doaj.org/article/0878eb4c17334e71a3a9f8cd1d35a457
Autor:
Susumu Tadokoro, Reiko Tokuyama-Toda, Seiko Tatehara, Shinji Ide, Hirochika Umeki, Keiko Miyoshi, Takafumi Noma, Kazuhito Satomura
Publikováno v:
Cells, Vol 10, Iss 11, p 2827 (2021)
Considering that every tissue/organ has the most suitable microenvironment for its functional cells, controlling induced pluripotent stem cell (iPSC) differentiation by culture on frozen sections having a suitable microenvironment is possible. Induce
Externí odkaz:
https://doaj.org/article/13f33f043a324e809017b77474f3db2d
Publikováno v:
Stem Cells International, Vol 2015 (2015)
Stem cell therapy appears to be promising for restoring damaged or irreparable lung tissue. However, establishing a simple and reproducible protocol for preparing lung progenitor populations is difficult because the molecular basis for alveolar epith
Externí odkaz:
https://doaj.org/article/07b2c0f8c48849a4a61b244f1ba5cbec
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89916 (2014)
Adenine nucleotide dynamics in the mitochondrial intermembrane space (IMS) play a key role in oxidative phosphorylation. In a previous study, Drosophila adenylate kinase isozyme 2 (Dak2) knockout was reported to cause developmental lethality at the l
Externí odkaz:
https://doaj.org/article/f100b59695574dcdb9531289c5de37ad
Publikováno v:
Journal of Oral Biosciences. 64:176-182
It is well-established that cervical lymph node metastasis is the most important prognostic factor in head and neck squamous cell carcinoma (HNSCC). Cancer cells invade the underlying stroma during metastasis by breaching the basement membrane.The ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c453b520f9ee2985bdd4ad29b8eda4
https://doi.org/10.1016/j.job.2022.02.004
https://doi.org/10.1016/j.job.2022.02.004