Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Keiko Miyashita"'
Autor:
Noriaki Arakawa, Atsuhito Ushiki, Mitsuhiro Abe, Shinichiro Matsuyama, Yoshinobu Saito, Takeru Kashiwada, Yasushi Horimasu, Akihiko Gemma, Koichiro Tatsumi, Noboru Hattori, Kenji Tsushima, Keiko Miyashita, Kosuke Saito, Ryosuke Nakamura, Takeshi Toyoda, Kumiko Ogawa, Motonobu Sato, Kazuhiko Takamatsu, Kazuhiko Mori, Takayoshi Nishiya, Takashi Izumi, Yasuo Ohno, Yoshiro Saito, Masayuki Hanaoka
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
No reliable serum biomarker for diffuse alveolar damage, a poor prognosis subtype of drug-induced interstitial lung disease, is currently available. Here, the authors show stratifin/14-3-3σ in serum is a promising biomarker for diagnosis of this typ
Externí odkaz:
https://doaj.org/article/26c767ba6b984eb3ba31e8f03b45e8ce
Autor:
Noriaki Arakawa, Shinichiro Matsuyama, Masaru Matsuoka, Isao Kitamura, Keiko Miyashita, Yutaro Kitagawa, Kazuo Imai, Kumiko Ogawa, Takuya Maeda, Yoshiro Saito, Chihiro Hasegawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 150, Iss 1, Pp 21-30 (2022)
The prognosis of patients with severe cases of COVID-19 is poor; thus, biomarkers for earlier prediction of COVID-19 progression are vital. We measured levels of five lung injury-related biomarkers, SP-D, KL-6, presepsin, kallistatin and stratifin, i
Externí odkaz:
https://doaj.org/article/950290dd22614200abf2e6e6d3336397
Autor:
Noriaki Arakawa, Atsuhito Ushiki, Mitsuhiro Abe, Shinichiro Matsuyama, Yoshinobu Saito, Takeru Kashiwada, Yasushi Horimasu, Akihiko Gemma, Koichiro Tatsumi, Noboru Hattori, Kenji Tsushima, Keiko Miyashita, Kosuke Saito, Ryosuke Nakamura, Takeshi Toyoda, Kumiko Ogawa, Motonobu Sato, Kazuhiko Takamatsu, Kazuhiko Mori, Takayoshi Nishiya, Takashi Izumi, Yasuo Ohno, Yoshiro Saito, Masayuki Hanaoka
Publikováno v:
Nature communications. 13(1)
Among the various histopathological patterns of drug-induced interstitial lung disease (DILD), diffuse alveolar damage (DAD) is associated with poor prognosis. However, there is no reliable biomarker for its accurate diagnosis. Here, we show stratifi
Autor:
Ko-ichi Kawahara, Makiko Emoto, Keiko Miyashita, Yoshiko Kawakami, Kiyoshi Kikuchi, Masayuki Tokuda, Syoko Tatsuyama, Yoko Morimoto-Yamashita
Publikováno v:
Medical Hypotheses. 85:618-621
Periodontitis is a chronic inflammatory disease that affects the tooth-supporting tissues. Gingival fibroblasts are the most abundant cells in periodontal tissues and they participate actively in the host inflammatory response to periodontal pathogen
Publikováno v:
Disease Markers
Disease Markers, Vol 2015 (2015)
Disease Markers, Vol 2015 (2015)
Alpha 2-HS glycoprotein (AHSG), also designated as fetuin-A, exhibits polymorphism in population genetics consisting of two major alleles ofAHSG∗1andAHSG∗2. The serum level in theAHSG∗1homozygote is significantly higher than that of theAHSG∗2
Autor:
Mari Fujisawa, Yoshiko Kawakami, Keiko Miyashita, Mitsuo Torii, Yoko Morimoto-Yamashita, Masayuki Tokuda
Publikováno v:
Connective Tissue Research. 56:44-49
To examine the responses of mouse odontoblast-lineage cell line (OLC) cultures to xylitol-induced hypertonic stress.OLCs were treated with xylitol, sucrose, sorbitol, mannitol, arabinose and lyxose. Cell viability was evaluated using the 3-(4,5-dimet
Autor:
Tomonori Tamura, Kiyoshi Minaguchi, Yu Kakimoto, Keiko Miyashita, Motoki Osawa, Yutaka Matsushima, Fumiko Satoh, Eriko Ochiai
Publikováno v:
Legal Medicine. 18:72-74
Parent–child analyses sometimes reveal inconsistency of shared alleles at only one locus. This is conventionally called "single locus exclusion", which results from mutational events and the presence of null alleles. Here, in parent–child analyse
Autor:
Chiharu Sato, Yumi Iida, Shin Ichiro Ohno, Katsuto Hozumi, Tatsuya Sugoh, Yoshinori Okada, Masanobu Satake, Hideyuki Saya, Kazuyoshi Kohu, Yasutoshi Agata, Marin Chiba, Akira Akatsuka, Tomoki Chiba, Sonoko Habu, Keiko Miyashita, Hisako Akatsuka, Hideyuki Tanabe, Takehito Sato
Publikováno v:
Journal of Immunology = Journal of Immunology. 189(9):4426-4436
After receiving a TCR-mediated differentiation signal, CD4 and CD8 double-positive thymocytes diverge into CD4 or CD8 single-positive T cells, for which Th-POK and Runx3 have been identified as pivotal transcription factors, respectively. The cross-a
Autor:
Keiko Miyashita, Yu Kakimoto, Masato Nakatome, Kiyoshi Minaguchi, Motoki Osawa, Phrabhakaran Nambiar, Fumiko Satoh, Eriko Ochiai
Publikováno v:
Legal medicine (Tokyo, Japan). 22
The Y chromosomal haplogroup determined from single nucleotide polymorphism (SNP) combinations is a valuable genetic marker to study ancestral male lineage and ethical distribution. Next-generation sequencing has been developed for widely diverse gen
Autor:
Ko-ichi Kawahara, Yoko Morimoto-Yamashita, Masayuki Tokuda, Mitsuo Torii, Kiyoshi Kikuchi, Makiko Emoto, Yoshiko Kawakami-Morizono, Keiko Miyashita, Mari Fijisawa, Takashi Ito, Shoko Tatsuyama-Nagayama
Publikováno v:
Medical Hypotheses. 79:452-455
Periodontitis is a major chronic inflammatory disease associated with increased production of numerous proinflammatory cytokines, which leads to the destruction of the periodontal tissue and ultimately loss of teeth. Periodontitis has powerful and mu