Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Keiko Mitsunaga-Nakatsubo"'
Autor:
Kazumasa Fujita, Naoko Teramura, Shinkichi Irie, Shunji Hattori, Keiko Mitsunaga-Nakatsubo, Takashi Yamamoto, Koji Akasaka, Naoaki Sakamoto, Yoshihiro Akimoto
Publikováno v:
Connective Tissue Research. 51:388-396
Inherited deficiency for arylsulfatase (Ars) leads to lysosomal storage of sulfated compounds and to serious diseases such as growth retardation, heart failure, and demyelination in the central nervous system. Ars has been regarded as a lysosomal enz
Autor:
Hiroka Iida, Ikuya Saito, Takashi Yamamoto, Koji Akasaka, Keiko Mitsunaga-Nakatsubo, Takayoshi Fujii, Naoaki Sakamoto
Publikováno v:
Gene Expression Patterns. 6:572-577
The Hemicentrotus pulcherrimus homologue of nanos (HpNanos), that encodes a protein containing two CCHC zinc finger motifs, was isolated from a gastrula cDNA library. The accumulation of HpNanos mRNA during embryonic development and the spatial expre
Autor:
Keiko Mitsunaga-Nakatsubo, Kosuke Shiomi, Rika Kawabata, Masaya Sawaguchi, Atsuko Yamazaki, Shonan Amemiya, Masaaki Yamaguchi
Publikováno v:
Development Genes and Evolution. 215:450-459
In the sea urchin embryo, micromeres have two distinct functions: they differentiate cell autonomously into the skeletogenic mesenchyme cells and act as an organizing center that induces endomesoderm formation. We demonstrated that micro1 controls mi
Autor:
Yasunori Hayashibara, Koji Akasaka, Keiko Mitsunaga-Nakatsubo, Naoaki Sakamoto, Taishin Shimotori, Takashi Yamamoto
Publikováno v:
ResearcherID
Two distinct types of orthodenticle-related (HpOtxE and HpOtxL) mRNA are transcribed from a single HpOtx gene by altering the transcription start site and by alternative splicing, and their expressions are differentially regulated during early develo
Autor:
Koji Akasaka, Manabu Kurita, Naoaki Sakamoto, Takashi Yamamoto, Kazuko Takata, Keiko Mitsunaga-Nakatsubo, Hitoshi Kondoh, Hiraku Shimada, Taishin Shimotori
Publikováno v:
Development Genes and Evolution. 213:44-49
We applied a particle gun method to introduce DNA into fertilized sea urchin eggs for the analysis of cis-regulatory elements responsible for spatial gene expression during development. We introduced HpArs (sea urchin arylsulfatase gene) –GFP and H
Autor:
Daisuke Kurokawa, Koji Akasaka, Takuya Fuchikami, Nori Satoh, Miho Kataoka, Keiko Mitsunaga-Nakatsubo, Toshiya Hosomi, Hiraku Shimada, Naoaki Sakamoto, Kazuko Takata, Taishin Shimotori, Takashi Watanabe, Takashi Yamamoto, Shinichiro Kusunoki, Yoshito Harada, Shonan Amemiya
Publikováno v:
Development. 129:5205-5216
Signals from micromere descendants play a crucial role in sea urchin development. In this study, we demonstrate that these micromere descendants express HpTb , a T-brain homolog of Hemicentrotus pulcherrimus. HpTb is expressed transiently from the ha
Autor:
Koji Akasaka, Keiko Mitsunaga-Nakatsubo, Kazuko Takata, Kaori Sasai, Takae Kiyama, Hiraku Shimada
Publikováno v:
Development Genes and Evolution. 210:583-590
A product of sea urchin homologues of the Drosophila orthodenticle gene, HpOtxL has been implicated as a transcription activator of the aboral ectoderm-specific arylsulfatase (Ars) gene during early development of the sea urchin embryo. Using an in v
Autor:
Koji Akasaka, Shonan Amemiya, Hiraku Shimada, Takashi Kitajima, Keiko Mitsunaga-Nakatsubo, Daisuke Kurokawa
Publikováno v:
Mechanisms of Development. 80(1):41-52
The mechanism of micromere specification is one of the central issues in sea urchin development. In this study we have identified a sea urchin homologue of ets 1 + 2. HpEts, which is maternally expressed ubiquitously during the cleavage stage and whi
Publikováno v:
Development, Growth and Differentiation. 40:537-544
Expression of the arylsulfatase (HpArs) gene in the sea urchin, Hemicentrotus pulcherrimus, is regulated in spatially, as well as temporally, during development. To address the cis-regulatory elements involved in this regulation, we performed reporte
Autor:
Koji Akasaka, Hiraku Shimada, Keiko Mitsunaga-Nakatsubo, Kazuko Takata, Naoaki Sakamoto, Takae Kiyama
Publikováno v:
Developmental Biology. 193(2):139-145
Two distinct types of orthodenticle-related proteins (HpOtxE/L) have been implicated as transcription activators of the aboral ectoderm-specific arylsulfatase (Ars) gene. Here, we describe the structure of HpOtx gene and present evidence that mRNAs o