Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Keiko Kasutani"'
Autor:
Yuki Iwayanagi, Kunihiro Hattori, Etsuko Fujii, Yoshiaki Takashima, Keiko Kasutani, Sohei Oyama, Masahiko Nanami, Hideki Adachi, Yoshiki Kawabe, Hidetomo Kitamura, Hiroaki Matsushita, Keiko Esaki, Akihisa Sakamoto, Tsukasa Suzuki, Taichi Kuramochi, Shin Shimaoka, Akihisa Kaneko, Masaaki Goto, Yoshinobu Higuchi
Publikováno v:
Experimental Dermatology. 27:14-21
Scratching is an important factor exacerbating skin lesions through the so-called itch-scratch cycle in atopic dermatitis (AD). In mice, interleukin (IL)-31 and its receptor IL-31 receptor A (IL-31RA) are known to play a critical role in pruritus and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f2a90eb76872e04193b80f0e55dbed
https://doi.org/10.1111/exd.13236
https://doi.org/10.1111/exd.13236
Autor:
Chiaki Senoh, Kiyotaka Nakano, Kunihiro Hattori, Osamu Natori, Hiroyuki Tsunoda, Keiko Kasutani, Tetsuo Kojima, Shinya Ishii
Publikováno v:
Journal of Immunological Methods. 347:31-35
Agonistic diabodies that mimic the function of natural ligands are expected to increase the value of therapeutic antibodies. We have developed a method that detects agonistic diabodies based on their ability to transduce growth signals through recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bb488a94ab109bd64ddca6eb4265ea
https://doi.org/10.1016/j.jim.2009.05.012
https://doi.org/10.1016/j.jim.2009.05.012
Autor:
N Yamashita, Keiko Kasutani, Hidetomo Kitamura, Etsuko Fujii, S Ohyama, Hideki Adachi, M Hasegawa
Publikováno v:
British Journal of Pharmacology.
Background and Purpose IL-31, which is described as a pruritogenic cytokine, is linked to the itching that is associated with allergic and non-allergic eczema, but the precise pruritogenic mechanism of IL-31 and its potential as a therapeutic target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25487cc44b071870d188f2d82bb57559
https://doi.org/10.1111/bph.12823
https://doi.org/10.1111/bph.12823
Autor:
Masahiko Mihara, Makoto Okazaki, Yoshiyuki Ohsugi, Shigeto Kawai, Akito Nakamura, Keiko Kasutani, Yoshihiro Matsumoto, Masamichi Sugimoto
Publikováno v:
International immunopharmacology. 5(12)
To characterize the biological activity of tocilizumab, a humanized anti-human interleukin-6 receptor (IL-6R) monoclonal antibody, we examined its binding activity to both soluble IL-6R (sIL-6R) and membrane bound IL-6R (mIL-6R) and its neutralizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b576208150a55cbd3a69420b5646fbb
https://pubmed.ncbi.nlm.nih.gov/16102523
https://pubmed.ncbi.nlm.nih.gov/16102523
Publikováno v:
Metallothionein IV ISBN: 9783034897990
Metallothionein (MT)-inducing activity of interleukin (IL)-6 depends on the presence of glucocorticoid in hepatic cells. The synergistic action of IL-6 and glucocorticoid was observed in the transcriptional activation of the mouse MT (mMT)-I gene. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73048943066db7251ab4ddac4e5f51ff
https://doi.org/10.1007/978-3-0348-8847-9_37
https://doi.org/10.1007/978-3-0348-8847-9_37
Publikováno v:
Toxicology and applied pharmacology. 151(1)
Metallothionein (MT)-inducing activity of interleukin (IL)-6 depends on the presence of glucocorticoid in hepatic cells. The synergistic action of IL-6 and glucocorticoid was observed in the transcriptional activation of the mouse MT (mMT)-I gene. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6e1d666b7bd7fc6e318b6bbd362b17
https://pubmed.ncbi.nlm.nih.gov/9705897
https://pubmed.ncbi.nlm.nih.gov/9705897
Publikováno v:
Toxicology. 112(1)
Although there is much evidence to suggest that lipopolysaccharide (LPS)-induced elevation of hepatic metallothionein (MT) contents is mediated by cytokines, the presence of MT-inducing activity in the serum of LPS-treated animals has not been examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2efac411c0f9f188a94a952ef4971fa1
https://pubmed.ncbi.nlm.nih.gov/8792846
https://pubmed.ncbi.nlm.nih.gov/8792846
Autor:
Oyama, Sohei1, Kitamura, Hidetomo1, Kuramochi, Taichi1, Higuchi, Yoshinobu1, Matsushita, Hiroaki1, Suzuki, Tsukasa1, Goto, Masaaki1, Adachi, Hideki1, Kasutani, Keiko1, Sakamoto, Akihisa1, Iwayanagi, Yuki1, Kaneko, Akihisa1, Nanami, Masahiko1, Fujii, Etsuko1, Esaki, Keiko1, Takashima, Yoshiaki1, Shimaoka, Shin1, Hattori, Kunihiro1, Kawabe, Yoshiki1 kawabeysk@chugai-pharm.co.jp
Publikováno v:
Experimental Dermatology. Jan2018, Vol. 27 Issue 1, p14-21. 8p.
Autor:
Sakurai, Takayuki, Takai, Ryo, Bürgin, Heinrich, Shioda, Akifumi, Sakamoto, Yuichiro, Amano, Jun, Grimm, Hans Peter, Richter, Wolfgang F., Higuchi, Yoshinobu, Chiba, Shuichi, Kawamura, Akinori, Suzuki, Masami, Müller, Lutz
Publikováno v:
Birth Defects Research. Part B: Developmental & Reproductive Toxicology; Apr2013, Vol. 98 Issue 2, p170-182, 13p
Autor:
C. Klaasen
The Proceedings of the Fourth International Metallothionein Meeting (MT-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both basic and clinical investigators. The sel