Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Keiko Inami"'
Publikováno v:
Genes and Environment, Vol 41, Iss 1, Pp 1-9 (2019)
Abstract Background An extract from Spatholobus suberectus (S. suberectus) Dunn has been reported to show potent antimutagenic effects against N-alkyl-N-nitrosoureas in umu screening. The aim of this study was to identify the antimutagenic components
Externí odkaz:
https://doaj.org/article/02963e1c6df049bf87a3990f1dfa4f28
Publikováno v:
Toxicology Research.
N-Nitrosamines are well known as environmental carcinogens. We have reported that N-nitroso-N-methylbutylamine was oxidized by Fe2+-Cu2+-H2O2 to 5-methyl-5-nitro-1-pyrazoline, a direct-acting N-oxide. 1-Pyrazolines have not been reported to exhibit g
Publikováno v:
HETEROCYCLES. 106:847
Publikováno v:
HETEROCYCLES. 106:680
Publikováno v:
HETEROCYCLES. 106:305
Publikováno v:
HETEROCYCLES. 104:326
Autor:
Keiko Inami1 inami@rs.noda.tus.ac.jp, Yusuke Mine1, Jin Tatsuzaki2, Chihiro Mori2, Masataka Mochizuki1
Publikováno v:
Genes & Environment. 1/6/2017, Vol. 39, p1-7. 7p.
Publikováno v:
Medicinal Chemistry Research. 26:3375-3383
A series of acridines with bifunctional substituents was synthesized with the dual properties of DNA alkylation and intercalation. 4,5-Bis(bromomethyl)acridine (1) was previously reported to crosslink and intercalate with DNA. In this study, 1,8-bis(
Publikováno v:
Toxicology Research. 6:173-178
Acetone alkylhydrazones have been reported to be mutagenic in Salmonella typhimurium TA1535 after exposure to oxygen, and the corresponding 2-alkylazo-2-propyl hydroperoxides are formed by autoxidation as a result. The aims of this study were to inve
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:3297-3302
N-Nitroso-N-methylurea (NMU) is a potent carcinogen and suspected as a cause of human cancer. In this study, mutagenic NMU was detected by HPLC after the transnitrosation of non-mutagenic N-nitrosoproline (NP) to N-methylurea in the presence of thiou