Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Keiko Furuhata"'
Publikováno v:
Journal of Immunotoxicology, Vol 18, Iss 1, Pp 163-172 (2021)
The importance of alveolar macrophages has been reported in many toxicology/immunology studies. Alveolar macrophages release interleukin (IL)-1α as a damage-associated molecular pattern (DAMP) when stimulated by fine particles. However, it is unclea
Externí odkaz:
https://doaj.org/article/bf20f18bee534a4699ffdafd55d99cb2
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009890 (2021)
Aluminum hydroxide salts (alum) have been added to inactivated vaccines as safe and effective adjuvants to increase the effectiveness of vaccination. However, the exact cell types and immunological factors that initiate mucosal immune responses to al
Externí odkaz:
https://doaj.org/article/15c234d22ce84c1fafd85299b4e18f64
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The efficacy of vaccine adjuvants depends on their ability to appropriately enhance the immunogenicity of vaccine antigens, which is often insufficient in non-adjuvanted vaccines. Genomic analyses of immune responses elicited by vaccine adjuvants pro
Externí odkaz:
https://doaj.org/article/aaa4b24302e5485aa9d7c0c5f627e3b3
Autor:
Eita Sasaki, Haruka Momose, Yuki Hiradate, Keiko Furuhata, Mamiko Takai, Hideki Asanuma, Ken J Ishii, Takuo Mizukami, Isao Hamaguchi
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191896 (2018)
Historically, vaccine safety assessments have been conducted by animal testing (e.g., quality control tests and adjuvant development). However, classical evaluation methods do not provide sufficient information to make treatment decisions. We previou
Externí odkaz:
https://doaj.org/article/fd7c97d77a1c4d09a3cd0830e1ab154e
Autor:
Haruka Momose, Takuo Mizukami, Madoka Kuramitsu, Kazuya Takizawa, Atsuko Masumi, Kumiko Araki, Keiko Furuhata, Kazunari Yamaguchi, Isao Hamaguchi
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124392 (2015)
We have previously identified 17 biomarker genes which were upregulated by whole virion influenza vaccines, and reported that gene expression profiles of these biomarker genes had a good correlation with conventional animal safety tests checking body
Externí odkaz:
https://doaj.org/article/88f7d529212a44f7ba89153bc820f836
Autor:
Takuo Mizukami, Haruka Momose, Madoka Kuramitsu, Kazuya Takizawa, Kumiko Araki, Keiko Furuhata, Ken J Ishii, Isao Hamaguchi, Kazunari Yamaguchi
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101835 (2014)
Vaccines are beneficial and universal tools to prevent infectious disease. Thus, safety of vaccines is strictly evaluated in the preclinical phase of trials and every vaccine batch must be tested by the National Control Laboratories according to the
Externí odkaz:
https://doaj.org/article/d5382bc4c8374a56bf4391d70774bc72
Autor:
Eita Sasaki1 esasaki@niid.go.jp, Keiko Furuhata1, Takuo Mizukami1 tmiz@niid.go.jp, Isao Hamaguchi1
Publikováno v:
Journal of Toxicological Sciences. 2022, Vol. 47 Issue 11, p439-451. 13p.
Autor:
Eita Sasaki, Hideki Asanuma, Haruka Momose, Keiko Furuhata, Takuo Mizukami, Takayuki Matsumura, Yoshimasa Takahashi, Isao Hamaguchi
Publikováno v:
Mucosal Immunology.
Publikováno v:
Journal of Immunotoxicology, Vol 18, Iss 1, Pp 163-172 (2021)
The importance of alveolar macrophages has been reported in many toxicology/immunology studies. Alveolar macrophages release interleukin (IL)-1α as a damage-associated molecular pattern (DAMP) when stimulated by fine particles. However, it is unclea
Autor:
Kaori Wakamatsu, Eita Sasaki, Keiko Furuhata, Takuo Mizukami, Hideki Kusunoki, Isao Hamaguchi, Haruka Momose, Kazuo Hosoda
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports
Scientific Reports
The safety evaluation of vaccines is critical to avoid the development of side effects in humans. To increase the sensitivity of detection for toxicity tests, it is important to capture not only pathological changes but also physiological changes. 1H