Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Keiko Fujihashi"'
Autor:
Yoshiko Fukuyama, Daisuke Tokuhara, Shinichi Sekine, Kazuyoshi Aso, Kosuke Kataoka, Julia Davydova, Masato Yamamoto, Rebekah S Gilbert, Yuka Tokuhara, Keiko Fujihashi, Jun Kunisawa, Yoshikazu Yuki, Hiroshi Kiyono, Jerry R McGhee, Kohtaro Fujihashi
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60453 (2013)
We assessed the role of CCR5(+)/CCR6(+)/CD11b(+)/CD11c(+) dendritic cells (DCs) for induction of ovalbumin (OVA)-specific antibody (Ab) responses following mucosal immunization. Mice given nasal OVA plus an adenovirus expressing Flt3 ligand (Ad-FL) s
Externí odkaz:
https://doaj.org/article/e67de8f7dd71445d98a0c9996ed96c13
Autor:
Kosuke Kataoka, Keiko Fujihashi, Yutaka Terao, Rebekah S Gilbert, Shinichi Sekine, Ryoki Kobayashi, Yoshiko Fukuyama, Shigetada Kawabata, Kohtaro Fujihashi
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25396 (2011)
Native cholera toxin (nCT) as a nasal adjuvant was shown to elicit increased levels of T-independent S-IgA antibody (Ab) responses through IL-5- IL-5 receptor interactions between CD4+ T cells and IgA+ B-1 B cells in murine submandibular glands (SMGs
Externí odkaz:
https://doaj.org/article/81971d897f2d44bf95fb5da06c944d96
Autor:
Hiromi Nagano, Gen SUGITA, rinya SUGITA, Yorihiko Ikeda, Keiko Fujihashi, Akitoshi Tsuruhara, Yuichi Kurono, Kohtaro Fujihashi
Publikováno v:
The Journal of Immunology. 198:147.7-147.7
Pneumococcal infection caused by Streptococcus pneumoniae is a major upper respiratory tract disease which causes severe illness and mortality. It is important to develop safe and effective vaccines to prevent pneumococcal infections. Sublingual (SL)
Autor:
Kohtaro Fujihashi, Hirotomo Kato, Frederik W. Van Ginkel, Toshiya Koga, Prosper N. Boyaka, Raymond J. Jackson, Rie Kato, Yukari Hagiwara, Yuri Etani, Iwao Goma, Keiko Fujihashi, Hiroshi Kiyono, Jerry R. McGhee
Publikováno v:
Acta Odontologica Scandinavica. 59:301-308
Induction of mucosal immunity by oral immunization with protein antigen alone is difficult: potent mucosal adjuvants, vectors, or other special delivery systems are required. Cholera toxin (CT) has been shown to be an effective adjuvant for the devel
Autor:
Junichiro Ohori, Hideki Asanuma, Kazuyoshi Aso, Yorihiko Ikeda, Gen Sugita, Keiko Fujihashi, Jerry McGhee, Kohtaro Fujihashi
Publikováno v:
The Journal of Immunology. 194:64.5-64.5
The elderly have already experienced various pathogens and thus possess pathogen-specific Abs, whose titers are too low to combat reinfection. Thus, it would be of great benefit to the aged population if one could use an innate adjuvant system alone,
Autor:
Shinichi Sekine, Kosuke Kataoka, Hideki Asanuma, Tatsuya Fukuiwa, Julia Davydova, Yasuo Adachi, Ryoki Kobayashi, Keiko Fujihashi, Satoshi Shizukuishi, Masato Yamamoto, Kohtaro Fujihashi
Publikováno v:
The Journal of Immunology. 178:LB23-LB23
Our previous study showed that targeting nasopharyngeal-associated lymphoreticular tissue (NALT) dendritic cells (DCs) with an adenovirus vector expressing Flt3 Ligand (Ad-FL) induced Ag-specific mucosal immunity that mediated by increased numbers of