Zobrazeno 1 - 10
of 229
pro vyhledávání: '"Keiko FURUKAWA"'
Autor:
Masayoshi Kawata, Atsushi Yonezawa, Yohei Mineharu, Kotaro Itohara, Toshiyuki Mizota, Yoshihiro Matsui, Takayuki Kikuchi, Yukihiro Yamao, Etsuko Yamamoto Hattori, Miho Hamada, Daiki Hira, Keiko Furukawa, Susumu Miyamoto, Tomohiro Terada, Kazuo Matsubara, Yoshiki Arakawa
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Propofol’s pharmacokinetics have been extensively studied using human blood samples and applied to target-controlled infusion systems; however, information on its concentration in the brain remains scarce. Therefore, this study aimed to si
Externí odkaz:
https://doaj.org/article/1d6cac383f944d16b7a93c10b969103c
Autor:
Etsuko Yamamoto Hattori, Yoshiki Arakawa, Yohei Mineharu, Keiko Furukawa, Yukinori Terada, Yukihiro Yamao, Masahiro Tanji, Takayuki Kikuchi, Susumu Miyamoto
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Epilepsy is a major symptom in patients with glioma. Levetiracetam (LEV) is recognized as a first-line treatment for glioma-related epilepsy. Increasing the LEV dose is allowed into patients with seizure occurrence against its ini
Externí odkaz:
https://doaj.org/article/64cbd2b46ffc49aeb50d228a82faa4ae
Publikováno v:
FEBS Open Bio, Vol 13, Iss 9, Pp 1615-1624 (2023)
Genetic disruption of glycosyltransferases has provided clear information on the roles of their reaction products in the body. Our group has studied the function of glycosphingolipids by genetic engineering of glycosyltransferases in cell culture and
Externí odkaz:
https://doaj.org/article/8cc4fd0b374948029e81dc2c818439ee
Autor:
Farhana Yesmin, Keiko Furukawa, Mariko Kambe, Yuhsuke Ohmi, Robiul Hasan Bhuiyan, Mohammad Abul Hasnat, Momoka Mizutani, Orie Tajima, Noboru Hashimoto, Akiko Tsuchida, Kei Kaneko, Koichi Furukawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Exosomes (small extracellular vesicles: EVs) have attracted increasing attention from basic scientists and clinicians since they play important roles in cell-to-cell communication in various biological processes. Various features of EVs have
Externí odkaz:
https://doaj.org/article/7702f35ab2754bb48b2a1bc84df9e75d
Autor:
Masayoshi KAWATA, Ayaka FUKUI, Yohei MINEHARU, Takayuki KIKUCHI, Yukihiro YAMAO, Etsuko YAMAMOTO HATTORI, Atsuko SHIRAKI, Toshiyuki MIZOTA, Keiko FURUKAWA, Susumu MIYAMOTO, Atsushi YONEZAWA, Yoshiki ARAKAWA
Publikováno v:
Neurologia Medico-Chirurgica, Vol 62, Iss 6, Pp 278-285 (2022)
The number of awake craniotomies is increasing because of its beneficial features. However, not enough information is available regarding the current status of awake craniotomy in Japan. To evaluate the current status of awake craniotomy in institute
Externí odkaz:
https://doaj.org/article/d83bd19bea814467951187470de82f4d
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281414 (2023)
Gangliosides, sialic acid-containing glycosphingolipids, are widely involved in regulations of signal transductions to control cellular functions. It has been suggested that GM3, the simplest structure among gangliosides, is involved in insulin resis
Externí odkaz:
https://doaj.org/article/b1ca69ebd0d6472bb6e3abc292f51d93
Autor:
Akiko Tsuchida, Motohiro Senda, Akihiro Ito, Seiichi Saito, Makoto Kiso, Takayuki Ando, Anne Harduin-Lepers, Akio Matsuda, Keiko Furukawa, Koichi Furukawa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract GalNAc-disialyl Lc4 (GalNAc-DSLc4) was reported as a novel antigen that associated with malignant features of renal cell cancers (RCCs). To clarify roles of GalNAc-DSLc4 in malignant properties of RCCs, we identified B4GalNAc-T2 as a respons
Externí odkaz:
https://doaj.org/article/6931623c8cee4e688a3f16eaa3d0c741
Autor:
Songhai Tian, Khaja Muneeruddin, Mei Yuk Choi, Liang Tao, Robiul H Bhuiyan, Yuhsuke Ohmi, Keiko Furukawa, Koichi Furukawa, Sebastian Boland, Scott A Shaffer, Rosalyn M Adam, Min Dong
Publikováno v:
PLoS Biology, Vol 16, Iss 11, p e2006951 (2018)
Glycosylation is a fundamental modification of proteins and membrane lipids. Toxins that utilize glycans as their receptors have served as powerful tools to identify key players in glycosylation processes. Here, we carried out Clustered Regularly Int
Externí odkaz:
https://doaj.org/article/0f48c87560b048dfb243742369a2031a
Autor:
Toru Yoshihara, Hiroyuki Satake, Toshikazu Nishie, Nozomu Okino, Toshihisa Hatta, Hiroki Otani, Chie Naruse, Hiroshi Suzuki, Kazushi Sugihara, Eikichi Kamimura, Noriyo Tokuda, Keiko Furukawa, Koichi Fururkawa, Makoto Ito, Masahide Asano
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007545 (2018)
It is uncertain which β4-galactosyltransferase (β4GalT; gene name, B4galt), β4GalT-5 and/or β4GalT-6, is responsible for the production of lactosylceramide (LacCer) synthase, which functions in the initial step of ganglioside biosynthesis. Here,
Externí odkaz:
https://doaj.org/article/14f22f1ec239459ebbbf8b434f7fbb61
Autor:
Yuhsuke Ohmi, Mariko Kambe, Yuki Ohkawa, Kazunori Hamamura, Orie Tajima, Rika Takeuchi, Koichi Furukawa, Keiko Furukawa
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206881 (2018)
Ganglioside GD3 is widely expressed in human malignant melanomas, and has been reported to be involved in the increased cell proliferation and invasion. In this study, we established GM3-, GM2-, GM1-, GD3-, or GD2-expressing melanoma cell lines by tr
Externí odkaz:
https://doaj.org/article/ccb531e332ca49d78e02bbb4138093cb