Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Keiko Danzaki"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Insulin and insulin-like growth factor 1 (IGF-1) are metabolic hormones with known effects on CD4+ T cells through insulin receptor (IR) and IGF-1 receptor (IGF-1R) signaling. Here, we describe specific and distinct roles for these hormones
Externí odkaz:
https://doaj.org/article/0d675f4c3a9a4de0927b2c906d221a20
Autor:
Yazan Alwarawrah, Keiko Danzaki, Amanda G. Nichols, Brian E. Fee, Cheryl Bock, Gary Kucera, Laura P. Hale, Gregory A. Taylor, Nancie J. MacIver
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Immunity Related GTPases (IRG) are a family of proteins produced during infection that regulate membrane remodeling events in cells, particularly autophagy and mitophagy. The human IRGM gene has been strongly associated with Crohn’s diseas
Externí odkaz:
https://doaj.org/article/9e50381ee66e446780fb21acef46e994
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 1, Pp 166-175 (2020)
Hearing loss: Disruption at the junction A decrease in the levels of connexin proteins at the junctions connecting cells in the inner-ear precedes age-related hearing loss (ARHL) in mice. Loss of hearing in the elderly is a growing problem in ageing
Externí odkaz:
https://doaj.org/article/7640c89328ff49b5ad14ee791772ad7e
Autor:
Ichiro Fukunaga, Yoko Oe, Keiko Danzaki, Sayaka Ohta, Cheng Chen, Madoka Iizumi, Takahiro Shiga, Rina Matsuoka, Takashi Anzai, Remi Hibiya-Motegi, Shori Tajima, Katsuhisa Ikeda, Wado Akamatsu, Kazusaku Kamiya
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102290- (2021)
The gap junction beta-2 (GJB2) gene is the most common genetic cause of hereditary deafness worldwide. Among them, the G45E/Y136X mutation in GJB2 is the third most prevalent in Japan. In this study, we generated two induced pluripotent stem cell (iP
Externí odkaz:
https://doaj.org/article/3f4ede43415d429eac1f2147b38eb85c
Autor:
Ichiro Fukunaga, Yoko Oe, Cheng Chen, Keiko Danzaki, Sayaka Ohta, Akito Koike, Katsuhisa Ikeda, Kazusaku Kamiya
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mutations in gap junction beta-2 (GJB2), the gene that encodes connexin 26 (CX26), are the most frequent cause of hereditary deafness worldwide. We recently developed an in vitro model of GJB2-related deafness (induced CX26 gap junction-forming cells
Externí odkaz:
https://doaj.org/article/bd15bdb00db34561822177d9a063769b
Autor:
Ichiro Fukunaga, Kyoko Shirai, Yoko Oe, Keiko Danzaki, Sayaka Ohta, Takahiro Shiga, Cheng Chen, Katsuhisa Ikeda, Wado Akamatsu, Atsushi Kawano, Kazusaku Kamiya
Publikováno v:
Stem Cell Research, Vol 47, Iss , Pp 101910- (2020)
The gap junction beta-2 (GJB2) gene is the most common genetic cause of hereditary deafness worldwide. Especially, the 235delC mutation in GJB2 is most prevalent in East Asia. In this study, we generated two iPSC lines from PBMCs of siblings carrying
Externí odkaz:
https://doaj.org/article/4d00595c8a70486c844851ce95c03fd0
Autor:
Ichiro Fukunaga, Takahiro Shiga, Cheng Chen, Yoko Oe, Keiko Danzaki, Sayaka Ohta, Rina Matsuoka, Takashi Anzai, Remi Hibiya-Motegi, Shori Tajima, Katsuhisa Ikeda, Wado Akamatsu, Kazusaku Kamiya
Publikováno v:
Stem Cell Research, Vol 43, Iss , Pp - (2020)
The gap junction beta-2 (GJB2) gene is the most common genetic cause of hereditary deafness worldwide. Especially, V37I mutation in GJB2 is most prevalent in Southeast Asia including Thailand, Malaysia, and Indonesia. Furthermore, it is the second mo
Externí odkaz:
https://doaj.org/article/daa88550283048028768a456886f5b9c
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 1, Pp 166-175 (2020)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Age-related hearing loss (ARHL) is the progressive, bilateral loss of high-frequency hearing in elderly people. Mutations in GJB2, encoding the cochlear gap junction protein connexin26 (Cx26), are the most frequent cause of hereditary deafness; howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17b0adc9f0d0414c0cf5523d4422049e
https://doaj.org/article/7640c89328ff49b5ad14ee791772ad7e
https://doaj.org/article/7640c89328ff49b5ad14ee791772ad7e
Autor:
Kazusaku Kamiya, Sayaka Ohta, Ichiro Fukunaga, Cheng Chen, Keiko Danzaki, Akito Koike, Katsuhisa Ikeda, Yoko Oe
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mutations in gap junction beta-2 (GJB2), the gene that encodes connexin 26 (CX26), are the most frequent cause of hereditary deafness worldwide. We recently developed an in vitro model of GJB2-related deafness (induced CX26 gap junction-forming cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ae0d507419cda14fbe3e04d4d71afc
Autor:
Takashi Anzai, Takahiro Shiga, Cheng Chen, Sayaka Ohta, Ichiro Fukunaga, Madoka Iizumi, Wado Akamatsu, Keiko Danzaki, Remi Hibiya-Motegi, Kazusaku Kamiya, Shori Tajima, Katsuhisa Ikeda, Yoko Oe, Rina Matsuoka
Publikováno v:
Stem Cell Research, Vol 53, Iss, Pp 102290-(2021)
The gap junction beta-2 (GJB2) gene is the most common genetic cause of hereditary deafness worldwide. Among them, the G45E/Y136X mutation in GJB2 is the third most prevalent in Japan. In this study, we generated two induced pluripotent stem cell (iP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f835f5047e0b3e1138990d604bb44beb
https://pubmed.ncbi.nlm.nih.gov/33780732
https://pubmed.ncbi.nlm.nih.gov/33780732