Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Keiko, Sekine"'
Publikováno v:
In Vaccine: X December 2022 12
Publikováno v:
Vaccine: X, Vol 12, Iss , Pp 100238- (2022)
According to the World Health Organization, the American region has the highest coronavirus disease-2019 (COVID-19) cases and deaths since the start of the pandemic. This humanitarian tragedy presented the possibility of generating efficacy data from
Externí odkaz:
https://doaj.org/article/5432060a355f4924bdaacab16e99c3aa
Autor:
Daichi Nagai, Osamu Miyazaki, Kazuya Okamoto, Eiji Ichimura, Yoshitaka Miyakawa, Tomio Morino, Keiko Ebara, Takeshi Onda, Keiko Sekine, Naoko Nakajima
Publikováno v:
International Journal of Cancer. 134:218-223
NK012 is a micelle-forming macromolecular prodrug of 7-ethyl-10-hydroxy camptothecin (SN-38), an active metabolite of irinotecan. It is accumulated and retained in tumor tissues and gradually releases SN-38 in an enzyme-independent manner. NK012 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::960c4d238a6c9a93120d26a162743376
https://doi.org/10.1002/ijc.28333
https://doi.org/10.1002/ijc.28333
Autor:
Kiyohiro Nishikawa, Mikihiko Naito, Takashi Tsuruo, Kohei Takubo, Fuminori Abe, Keiko Sekine, Masayuki Kitagawa, Michie Nishimoto, Ryo Kikuchi
Publikováno v:
Journal of Biological Chemistry. 283:8961-8968
Overexpression of an anti-apoptotic protein cIAP1 caused by its genetic amplification was reported in certain cancers, such as hepatocellular carcinoma, esophageal squamous cell carcinoma, cervical cancer, and lung cancer, which confers resistance to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::633ef56806728953cc3334ecda0b850f
https://doi.org/10.1074/jbc.m709525200
https://doi.org/10.1074/jbc.m709525200
Publikováno v:
Biological and Pharmaceutical Bulletin. 29:709-712
Bestatin is an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B. In our previous report, bestatin inhibited the tumor cell invasion and the angiogenesis induced by the inoculation of B16-BL6 melanoma cells into mice and capillary formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00654b7c9569e0f52b99b3e27a2f795
https://doi.org/10.1248/bpb.29.709
https://doi.org/10.1248/bpb.29.709
Autor:
Hirokazu Ohata, Ryohei Katayama, Keiko Sekine, Chizuko Hashimoto, Yanyan Hao, Hitoshi Nakamura, Atsushi Kawabata, Mikihiko Naito, Takashi Tsuruo, Toshiyasu Ishioka, Tetsuo Noda, Xiaodong Zhang
Publikováno v:
Nature Cell Biology. 6:849-860
Apollon (also known as BRUCE or BIRC6) is a large protein containing baculoviral-IAP-repeat (BIR) and ubiquitin-conjugating enzyme (UBC) domains at the amino- and carboxy termini, respectively. Apollon inhibits apoptosis, but its molecular and physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a2f28227ae760ad169af02b6ffc830
https://doi.org/10.1038/ncb1159
https://doi.org/10.1038/ncb1159
Publikováno v:
International Journal of Cancer. 94:485-491
We previously reported that the aminopeptidase inhibitor bestatin induced apoptosis in several human leukemia cell lines. The present study was performed to examine whether bestatin can also induce apoptosis in solid tumor cell lines. Bestatin alone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0d51f5e78031e1bff29539b3c2cdfbd
https://doi.org/10.1002/ijc.1492
https://doi.org/10.1002/ijc.1492
Autor:
Mineaki Okada, Momoe Kudo, Chaiyo Chaichantipyuth, Tsutomu Ishikawa, Yoshihiro Higuchi, Sunee Chansakaow, Keiko Sekine
Publikováno v:
Planta Medica. 66:572-575
Nine isoflavonoids including a new pterocarpene, puemiricarpene, were isolated from the tuberous root of Pueraria mirifica (Leguminosae). The structure of puemiricarpene was determined by spectroscopic means. Estrogenic activity of the isolated isofl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0329d5d947a0694f160fd628ceca22bb
https://doi.org/10.1055/s-2000-8603
https://doi.org/10.1055/s-2000-8603
Autor:
Osamu, Miyazaki, Keiko, Sekine, Naoko, Nakajima, Eiji, Ichimura, Keiko, Ebara, Daichi, Nagai, Takeshi, Onda, Yoshitaka, Miyakawa, Kazuya, Okamoto, Tomio, Morino
Publikováno v:
International journal of cancer. 134(1)
NK012 is a micelle-forming macromolecular prodrug of 7-ethyl-10-hydroxy camptothecin (SN-38), an active metabolite of irinotecan. It is accumulated and retained in tumor tissues and gradually releases SN-38 in an enzyme-independent manner. NK012 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a166c5dbe4373c49fe0cee7da092e241
https://pubmed.ncbi.nlm.nih.gov/23775066
https://pubmed.ncbi.nlm.nih.gov/23775066
Autor:
Sunee Chansakaow, Mineaki Okada, Tsutomu Ishikawa, Hiroko Seki, Keiko Sekine, Chaiyo Chaichantipyuth
Publikováno v:
Journal of Natural Products. 63:173-175
Miroestrol (1) has been isolated previously as an active principle from "Kwao Keur" (Pueraria mirifica), a rejuvenating folk medicine from Thailand. Reinvestigation using bioassay-guided purification has resulted in the isolation of a new potent phyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e8a9a182c3e804b22046a26ad30043
https://doi.org/10.1021/np990547v
https://doi.org/10.1021/np990547v