Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Keiko, Nakamichi"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 126, Iss 2, Pp 164-167 (2014)
Abstract.: Patients with psychiatric disorders, including schizophrenia, are reported to suffer from sleep disorders. In this study, we investigated the effects of lurasidone, an atypical antipsychotic, on sleep architecture in rats using sleep elect
Externí odkaz:
https://doaj.org/article/0e6b5d0e100f47be93cc89aa69478845
Autor:
Hiroyuki Nishikawa, Scott H Wilkinson, Taryn J. Corriveau, Antony Loebel, Keiko Nakamichi, Seth C. Hopkins, Kenneth S. Koblan
Publikováno v:
Clinical Pharmacology and Therapeutics
In contrast to the dose-occupancy relationship in the treatment of schizophrenia, the minimal effective level of dopamine receptor 2 (D2R) blockade for antipsychotics in the treatment of bipolar depression is unknown. Lower doses aimed at reducing ex
Publikováno v:
Journal of Pharmacological Sciences, Vol 126, Iss 2, Pp 164-167 (2014)
Introduction Patients with psychiatric disorders, including schizophrenia and bipolar disorder, are reported to suffer from sleep disorders. Objective To investigate the effects of lurasidone on sleep architecture in rats using sleep electroencephalo
Autor:
Masanori Yamamoto, Keiko Nakamichi, Satoko Baba, Harumi Matsuda, Kenji Matsumoto, Yuji Matsumoto, Taro Kato, Kazuki Yabuuchi, Haruka Nishimuta
Publikováno v:
Pharmacology Research & Perspectives
Enhancement of serotonergic neurotransmission has been the main stream of treatment for patients with depression. However, delayed therapeutic onset and undesirable side effects are major drawbacks for conventional serotonin reuptake inhibitors. Here
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 63
Dopamine plays a key role in the regulation of sleep–wake states, as revealed by the observation that dopamine-releasing agents such as methylphenidate have wake-promoting effects. However, the precise mechanisms for the wake-promoting effect produ
Autor:
Makoto Oka, Tomoko Kinoshita, Kiyoshi Furukawa, Keiko Nakamichi, Hitoshi Kohayakawa, Atsuko Kita, Yoshiaki Ochi, Kurumiya Satoshi
Publikováno v:
British Journal of Pharmacology. 142:1059-1072
We investigated the ability of N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide (AC-5216), a novel mitochondrial benzodiazepine receptor (MBR) ligand, to produce anti-anxiety and antidepressant-like effects in various a
Publikováno v:
European journal of pharmacology. 745
We have previously reported that AC-3933, a newly developed benzodiazepine receptor partial inverse agonist, facilitates acetylcholine release in the hippocampus and ameliorates scopolamine-induced memory deficits in rats. To further confirm the proc
Autor:
Atsuko, Kita, Hitoshi, Kohayakawa, Tomoko, Kinoshita, Yoshiaki, Ochi, Keiko, Nakamichi, Satoshi, Kurumiya, Kiyoshi, Furukawa, Makoto, Oka
Publikováno v:
British journal of pharmacology. 142(7)
We investigated the ability of N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide (AC-5216), a novel mitochondrial benzodiazepine receptor (MBR) ligand, to produce anti-anxiety and antidepressant-like effects in various a