Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Keiko, Mikami"'
Autor:
Yosuke Tanaka, Reina Takeda, Tsuyoshi Fukushima, Keiko Mikami, Shun Tsuchiya, Moe Tamura, Keito Adachi, Terumasa Umemoto, Shuhei Asada, Naoki Watanabe, Soji Morishita, Misa Imai, Masayoshi Nagata, Marito Araki, Hitoshi Takizawa, Tomofusa Fukuyama, Chrystelle Lamagna, Esteban S. Masuda, Ryoji Ito, Susumu Goyama, Norio Komatsu, Tomoiku Takaku, Toshio Kitamura
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Leukemic stem cells (LSCs) in chronic myeloid leukemia are resistant to imatinib and therefore are a cause of relapse. The authors show that IRAK1/4-NF-κB-PD-L1 signaling is critical to mediate imatinib resistance in LSCs and that combining imatinib
Externí odkaz:
https://doaj.org/article/c3477c962caf480e9537b3db7eabd49c
Autor:
Hitoshi Takizawa, Keito Adachi, Esteban Masuda, Masayoshi Nagasawa, Soji Morishita, Toshio Kitamura, Tomoiku Takaku, Terumasa Umemoto, Yosuke Tanaka, Marito Araki, Tomofusa Fukuyama, Chrystelle Lamagna, Moe Tamura, Shun Tsuchiya, Susumu Goyama, Misa Imai, Naoki Watanabe, Keiko Mikami, Norio Komatsu, Tsuyoshi Fukushima, Ryoji Ito
Leukemia stem cells (LSCs) in chronic myeloid leukemia (CML) are quiescent, insensitive to BCR-ABL1 tyrosine kinase inhibitors (TKIs) and responsible for CML relapse. Therefore, eradicating quiescent CML LSCs is a major goal in CML therapy. Here, usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3caae11f9e210e19afb8be0803b576a
https://doi.org/10.21203/rs.3.rs-449398/v1
https://doi.org/10.21203/rs.3.rs-449398/v1
Autor:
Yasutaka Hayashi, Kimihito C. Kawabata, Yosuke Tanaka, Yasufumi Uehara, Yo Mabuchi, Koichi Murakami, Akira Nishiyama, Shigeru Kiryu, Yusuke Yoshioka, Yasunori Ota, Tatsuki Sugiyama, Keiko Mikami, Moe Tamura, Tsuyoshi Fukushima, Shuhei Asada, Reina Takeda, Yuya Kunisaki, Tomofusa Fukuyama, Kazuaki Yokoyama, Tomoyuki Uchida, Masao Hagihara, Nobuhiro Ohno, Kensuke Usuki, Arinobu Tojo, Yoshio Katayama, Susumu Goyama, Fumio Arai, Tomohiko Tamura, Takashi Nagasawa, Takahiro Ochiya, Daichi Inoue, Toshio Kitamura
Publikováno v:
Cell Reports. 39:110805
Myelodysplastic syndrome (MDS) is a clonal disorder of hematopoietic stem cells (HSCs), characterized by ineffective hematopoiesis and frequent progression to leukemia. It has long remained unresolved how MDS cells, which are less proliferative, inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5ae53e36f7e5817f38e0de7daae2af
https://doi.org/10.1016/j.celrep.2022.110805
https://doi.org/10.1016/j.celrep.2022.110805
Autor:
Keiko, Mikami
一般社団法人 日本放射線看護学会 第９回学術集会 抄録集に掲載 【目的】患者にやさしい治療法とされている放射線治療は、線量の病巣への集中化を図るための機器・技術開発が急速に
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::652c2259a1d8517338c0990d4b7975b3
https://repo.qst.go.jp/records/82003
https://repo.qst.go.jp/records/82003
Autor:
Toshio Kitamura, Tsuyoshi Fukushima, Keiko Mikami, Susumu Goyama, Yosuke Tanaka, Keito Adachi, Tomofusa Fukuyama
Publikováno v:
Experimental hematology. 90
Chronic myeloid leukemia (CML) is a hematopoietic stem cell disorder caused by constitutively active BCR-ABL1 tyrosine kinase resulting from the t(9;22) Philadelphia translocation. Imatinib, a BCR-ABL1 tyrosine kinase inhibitor (TKI), is a revolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97cd2a14d81e45b7ee93b733288b072
https://pubmed.ncbi.nlm.nih.gov/32910995
https://pubmed.ncbi.nlm.nih.gov/32910995
Autor:
Tatsuki Sugiyama, Arinobu Tojo, Takahiro Ochiya, Daichi Inoue, Reina Takeda, Moe Tamura, Yasufumi Uehara, Yasunori Ota, Toshio Kitamura, Kazuaki Yokoyama, Kimihito Cojin Kawabata, Tsuyoshi Fukushima, Yoshio Katayama, Shigeru Kiryu, Yosuke Tanaka, Yuya Kunisaki, Takashi Nagasawa, Susumu Goyama, Tomofusa Fukuyama, Shuhei Asada, Keiko Mikami, Fumio Arai, Y Hayashi, Yusuke Yoshioka, Yo Mabuchi
Publikováno v:
Blood. 136:17-18
Myelodysplastic syndromes (MDS) is a clonal disorder of hematopoietic stem cells (HSCs) characterized by clonal hematopoietic stem cells (HSCs) with cytopenia, morphological abnormalities, genetic alteration, ineffective normal hematopoiesis, and fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a85e7fc5578d55eef9f2040318206b2
https://doi.org/10.1182/blood-2020-142284
https://doi.org/10.1182/blood-2020-142284
Autor:
Berthold Göttgens, Shuhei Asada, Tsuyoshi Fukushima, Hiroaki Honda, Y Hayashi, Keiko Mikami, Fiona K. Hamey, Terumasa Umemoto, Chih-Hsiang Chang, Yasushi Ishihama, Kimihito Cojin Kawabata, Susumu Goyama, Reina Takeda, Toshio Kitamura, Toshihiko Oki, Takeshi Fujino, Hitoshi Takizawa, Yosuke Tanaka, Tomofusa Fukuyama, Taishi Yonezawa
Publikováno v:
SSRN Electronic Journal.
Quiescent hematopoietic stem cells (HSCs) are typically dormant, and only a few quiescent HSCs are active. The relationship between “dormant” and “active” HSCs remains unresolved. Here we generated a G0 marker mouse line that visualizes quies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e7c176c0036f2076c2ce4fd303d6e9e
https://doi.org/10.2139/ssrn.3312121
https://doi.org/10.2139/ssrn.3312121
Publikováno v:
山梨学院短期大学研究紀要. 32:134-146
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::25504865068b8c01e22d0a7849061ce1
http://id.nii.ac.jp/1188/00000115/
http://id.nii.ac.jp/1188/00000115/
Publikováno v:
山梨学院短期大学研究紀要. :95-110
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::5b460bfe698f8674a95c4f7ede07fdbe
http://id.nii.ac.jp/1188/00001691/
http://id.nii.ac.jp/1188/00001691/
Publikováno v:
山梨学院短期大学研究紀要. :73-79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::b7e297df18e1b02f0ede94300583871d
http://id.nii.ac.jp/1188/00001730/
http://id.nii.ac.jp/1188/00001730/