Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Keiko, Iwaisako"'
Autor:
Satoshi Kozuki, Mio Kabata, Satoko Sakurai, Keiko Iwaisako, Tomomi Nishimura, Masakazu Toi, Takuya Yamamoto, Fumiko Toyoshima
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract The maternal liver is challenged by metabolic demands throughout pregnancy. However, hepatocyte dynamics and their physiological significance in pregnancy remain unclear. Here, we show in mice that hepatocyte proliferation is spatiotemporall
Externí odkaz:
https://doaj.org/article/f976d490a1cb4bc8907d2518f26a4946
Autor:
Etsushi Kawamura, Tsutomu Matsubara, Atsuko Daikoku, Sanae Deguchi, Masahiko Kinoshita, Hideto Yuasa, Hayato Urushima, Naoshi Odagiri, Hiroyuki Motoyama, Kohei Kotani, Ritsuzo Kozuka, Atsushi Hagihara, Hideki Fujii, Sawako Uchida‐Kobayashi, Shogo Tanaka, Shigekazu Takemura, Keiko Iwaisako, Masaru Enomoto, Y. H. Taguchi, Akihiro Tamori, Shoji Kubo, Kazuo Ikeda, Norifumi Kawada
Publikováno v:
FEBS Open Bio, Vol 12, Iss 12, Pp 2122-2135 (2022)
Cholangiocarcinoma (CC) has a poor prognosis and different driver genes depending on the site of onset. Intrahepatic CC is the second‐most common liver cancer after hepatocellular carcinoma, and novel therapeutic targets are urgently needed. The pr
Externí odkaz:
https://doaj.org/article/c453312f01b14c94a9d40862ce06458b
Autor:
Hirokazu Okada, Ken Takahashi, Hiroaki Yaku, Kouji Kobiyama, Keiko Iwaisako, Xiangdong Zhao, Masahiro Shiokawa, Norimitsu Uza, Yuzo Kodama, Ken J. Ishii, Hiroshi Seno
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Although checkpoint inhibitors (CPIs) have changed the paradigm of cancer therapy, low response rates and serious systemic adverse events remain challenging. In situ vaccine (ISV), intratumoral injection of immunomodulators that stimulate in
Externí odkaz:
https://doaj.org/article/12fbcc7326ec4f2aaa2b0349a2d4b50f
Autor:
Takahiro Nishio, Yukinori Koyama, Hiroaki Fuji, Kei Ishizuka, Keiko Iwaisako, Kojiro Taura, Etsuro Hatano, David A. Brenner, Tatiana Kisseleva
Publikováno v:
Biology, Vol 11, Iss 11, p 1589 (2022)
Fibrosis is a common consequence of abnormal wound healing, which is characterized by infiltration of myofibroblasts and formation of fibrous scar. In liver fibrosis, activated Hepatic Stellate Cells (aHSCs) and activated Portal Fibroblasts (aPFs) ar
Externí odkaz:
https://doaj.org/article/34b4b401b4e04b70aec2d303d8b03733
Autor:
Kazufumi Honda, Takako Hishiki, Sohei Yamamoto, Takehiro Yamamoto, Nami Miura, Akiko Kubo, Mai Itoh, Wei-Yu Chen, Masashi Takano, Tomoyuki Yoshikawa, Takahiro Kasamatsu, Shinichiro Sonoda, Hirotoshi Yoshizawa, Seigo Nakamura, Yuichiro Itai, Megumi Shiota, Daisuke Koike, Masayuki Naya, Noriyo Hayakawa, Yoshiko Naito, Tomomi Matsuura, Keiko Iwaisako, Toshihiko Masui, Shinji Uemoto, Kengo Nagashima, Yoshinori Hashimoto, Tomohiro Sakuma, Osamu Matsubara, Wilber Huang, Tomoaki Ida, Takaaki Akaike, Yohei Masugi, Michiie Sakamoto, Tomoyasu Kato, Yoshinori Ino, Hiroshi Yoshida, Hitoshi Tsuda, Nobuyoshi Hiraoka, Yasuaki Kabe, Makoto Suematsu
Publikováno v:
Redox Biology, Vol 44, Iss , Pp 102028- (2021)
Externí odkaz:
https://doaj.org/article/3632cee4da7d4f8db285cb77e38f3302
Autor:
Kazufumi Honda, Takako Hishiki, Sohei Yamamoto, Takehiro Yamamoto, Nami Miura, Akiko Kubo, Mai Itoh, Wei-Yu Chen, Masashi Takano, Tomoyuki Yoshikawa, Takahiro Kasamatsu, Shinichiro Sonoda, Hirotoshi Yoshizawa, Seigo Nakamura, Yuichiro Itai, Megumi Shiota, Daisuke Koike, Masayuki Naya, Noriyo Hayakawa, Yoshiko Naito, Tomomi Matsuura, Keiko Iwaisako, Toshihiko Masui, Shinji Uemoto, Kengo Nagashima, Yoshinori Hashimoto, Tomohiro Sakuma, Osamu Matsubara, Wilber Huang, Tomoaki Ida, Takaaki Akaike, Yohei Masugi, Michiie Sakamoto, Tomoyasu Kato, Yoshinori Ino, Hiroshi Yoshida, Hitoshi Tsuda, Nobuyoshi Hiraoka, Yasuaki Kabe, Makoto Suematsu
Publikováno v:
Redox Biology, Vol 41, Iss , Pp 101926- (2021)
Chemosensitivity to cisplatin derivatives varies among individual patients with intractable malignancies including ovarian cancer, while how to unlock the resistance remain unknown. Ovarian cancer tissues were collected the debulking surgery in disco
Externí odkaz:
https://doaj.org/article/9f24b5a3426c4b619489a11ecbc675aa
Autor:
Keita Fukuyama, Masataka Asagiri, Masahiro Sugimoto, Hiraki Tsushima, Satoru Seo, Kojiro Taura, Shinji Uemoto, Keiko Iwaisako
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0245939 (2021)
Cancer cell lines are widely used in basic research to study cancer development, growth, invasion, or metastasis. They are also used for the development and screening of anticancer drugs. However, there are no clear criteria for choosing the most sui
Externí odkaz:
https://doaj.org/article/49e6666ec4844754a58be78981abc160
Autor:
Soki Kashima, Takuya Maeda, Kyoko Masuda, Seiji Nagano, Takamitsu Inoue, Masashi Takeda, Yuka Kono, Takashi Kobayashi, Shigeyoshi Saito, Takahiro Higuchi, Hiroshi Ichise, Yuka Kobayashi, Keiko Iwaisako, Koji Terada, Yasutoshi Agata, Kazuyuki Numakura, Mitsuru Saito, Shintaro Narita, Masaki Yasukawa, Osamu Ogawa, Tomonori Habuchi, Hiroshi Kawamoto
Publikováno v:
iScience, Vol 23, Iss 4, Pp - (2020)
Summary: Current adoptive T cell therapies conducted in an autologous setting are costly, time consuming, and depend on the quality of the patient's T cells. To address these issues, we developed a strategy in which cytotoxic T lymphocytes (CTLs) are
Externí odkaz:
https://doaj.org/article/8642056a6e3e46368c7a690d7178da9a
Autor:
Yoshinobu Ikeno, Satoru Seo, Keiko Iwaisako, Tomoaki Yoh, Yuji Nakamoto, Hiroaki Fuji, Kojiro Taura, Hideaki Okajima, Toshimi Kaido, Shimon Sakaguchi, Shinji Uemoto
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-9 (2018)
Abstract Background Surgical resection remains the mainstay of curative treatment for intrahepatic cholangiocarcinoma (ICC). Prognosis after surgery is unsatisfactory despite improvements in treatment and post-operative clinical management. Despite d
Externí odkaz:
https://doaj.org/article/30f31cd0f71741669aa26b46fe036634
Autor:
Yusuke Uemoto, Kojiro Taura, Daichi Nakamura, Li Xuefeng, Nguyen Hai Nam, Yusuke Kimura, Kenji Yoshino, Hiroaki Fuji, Tomoaki Yoh, Takahiro Nishio, Gen Yamamoto, Yukinori Koyama, Satoru Seo, Tatsuaki Tsuruyama, Keiko Iwaisako, Shinji Uemoto, Yasuhiko Tabata, Etsuro Hatano
Publikováno v:
Tissue Engineering Part A. 28:737-748
Although choledochojejunostomy is the standard technique for biliary reconstruction, there are various associated problems that need to be solved such as reflux cholangitis. Interposition with an artificial bile duct (ABD) to replace the resected bil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0601ec03196fe4d3333afb9141e877
https://doi.org/10.1089/ten.tea.2021.0209
https://doi.org/10.1089/ten.tea.2021.0209