Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Keiki Sakurama"'
Autor:
Keiki Sakurama, Yuki Iguchi, Sara Haruki, Yusuke Hata, Madoka Hiraga, Shinya Yumoto, Yutaka Kai
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 9, Iss 1, Pp 1-4 (2023)
Abstract Background Rhabdomyolysis is a potentially life-threatening disease caused by melting or necrosis of skeletal muscle cells and leakage of muscle components into the bloodstream. It has been reported that the interaction of the HMG-CoA reduct
Externí odkaz:
https://doaj.org/article/ae13b20a04e841678507c056e1ecaabc
Autor:
Kenshiro Hirata, Akito Kawai, Victor Tuan Giam Chuang, Keiki Sakurama, Koji Nishi, Keishi Yamasaki, Masaki Otagiri
Publikováno v:
ACS Omega, Vol 7, Iss 5, Pp 4413-4419 (2022)
Externí odkaz:
https://doaj.org/article/f99ee7371bde438d8a3267907352f9af
Autor:
Keiki Sakurama, Yuki Iguchi, Sara Haruki, Yusuke Hata, Madoka Hiraga, Shinya Yumoto, Yutaka Kai
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences, Vol 9, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/35b36ca76cfd4053b36d49654f060089
Autor:
Keiki Sakurama, Akito Kawai, Victor Tuan Giam Chuang, Yoko Kanamori, Miyu Osa, Kazuaki Taguchi, Hakaru Seo, Toru Maruyama, Shuhei Imoto, Keishi Yamasaki, Masaki Otagiri
Publikováno v:
ACS Omega, Vol 3, Iss 10, Pp 13790-13797 (2018)
Externí odkaz:
https://doaj.org/article/be5ffa2d551b4f0b8fa70732480f3651
Autor:
Kenshiro Hirata, Tokunori Ikeda, Hiroshi Watanabe, Toru Maruyama, Motoko Tanaka, Victor Tuan Giam Chuang, Yuji Uchida, Keiki Sakurama, Koji Nishi, Keishi Yamasaki, Masaki Otagiri
Publikováno v:
Toxins, Vol 13, Iss 11, p 811 (2021)
The binding of drugs to plasma protein is frequently altered in certain types of renal diseases. We recently reported on the effects of oxidation and uremic toxins on the binding of aripiprazole (ARP) to human serum albumin. In our continuing investi
Externí odkaz:
https://doaj.org/article/5521bd7ff6104aa1a466933dd37f6b68
Autor:
Kenji Tsukigawa, Keishi Yamasaki, Hakaru Seo, Masaki Otagiri, Koji Nishi, Kazuaki Taguchi, Keiki Sakurama
Publikováno v:
Journal of Pharmacy and Pharmacology. 74:88-93
Objectives Echinocandins are widely used for the treatment of invasive fungal diseases. While they bind strongly to plasma proteins, our knowledge of this process is not sufficient to permit their pharmacokinetics and pharmacodynamics targets to be d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5103f2b88486afa713e5f5a95b2f2d
https://doi.org/10.1093/jpp/rgab157
https://doi.org/10.1093/jpp/rgab157
Autor:
Yuta Yoshino, Yuki Saito, Nagiko Udo, Kenji Tsukigawa, Masaki Otagiri, Keishi Yamasaki, Koji Nishi, Keiki Sakurama, Akito Kawai
Publikováno v:
Molecular Pharmaceutics. 18:1061-1070
Benzbromarone has been used for the treatment of gout for more than 30 years. Although it shows a high level of binding to plasma proteins (>99%), our knowledge of this binding is not sufficiently extensive to permit us to understand its pharmacokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab9c55a31bbbf9b8817921bfc751174
https://doi.org/10.1021/acs.molpharmaceut.0c01004
https://doi.org/10.1021/acs.molpharmaceut.0c01004
Autor:
Koji Nishi, Mai Hashimoto, Shuhei Imoto, Masaki Otagiri, Hiroshi Morioka, Keiki Sakurama, Keishi Yamasaki, Nagiko Udo, Yoshihiro Kobashigawa
Publikováno v:
Journal of Pharmaceutical Sciences. 108:3911-3916
We recently reported that aripiprazole binds strongly to human albumin. In continuing our investigations, we investigated the mechanism responsible for the binding and the related interactions of aripiprazole with α1-acid glycoprotein (AGP). The ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0b6d56e7ededb337ebc024aa43560d1
https://doi.org/10.1016/j.xphs.2019.09.003
https://doi.org/10.1016/j.xphs.2019.09.003
Autor:
Kenshiro Hirata, Akito Kawai, Victor Tuan Giam Chuang, Keiki Sakurama, Koji Nishi, Keishi Yamasaki, Masaki Otagiri
Publikováno v:
ACS Omega, Vol 7, Iss 5, Pp 4413-4419 (2022)
The effects of myristate on the induced circular dichroism spectra of aripiprazole (ARP) bound to human serum albumin (HSA) were investigated. High concentrations of myristate reversed the Cotton effects induced in the ARP-HSA system. The observed el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9837032aa0706b7e44771fd3d90602fc
https://pubmed.ncbi.nlm.nih.gov/35155934
https://pubmed.ncbi.nlm.nih.gov/35155934
Publikováno v:
Biologicalpharmaceutical bulletin. 44(3)
We recently reported that aripiprazole (ARP), an antipsychotic drug, binds strongly to human serum albumin (HSA), the major drug binding protein in serum. It is known that uremic toxins that accumulate during renal disease affect the interaction betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbdc2ec72edcd3b2ffa0828cfb8a998c
https://pubmed.ncbi.nlm.nih.gov/33642552
https://pubmed.ncbi.nlm.nih.gov/33642552