Výsledky vyhledávání - "Keiji Shiroyama"

Percutaneous absorption of interferon-α by self-dissolving micropiles

Autor: Keiji Shiroyama, Atsushi Saeki, Yukako Ito, Kanji Takada, Nobuyuki Sugioka

Publikováno v: Journal of Drug Targeting. 16:243-249

To ascertain the pharmaceutical usefulness of self-dissolving micropiles (SDMPs) containing interferon (IFN), two types of SDMPs were prepared using chondroitin sulfate and dextran as the base. After percutaneous administration of 5000 IU/kg IFN-alph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1b403f356db1e7249ceb3353ae0c19
https://doi.org/10.1080/10611860801902575

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Pharmacokinetic and pharmacodynamic studies following percutaneous absorption of erythropoietin micropiles to rats

Autor: Kanji Takada, Jun-Ichiro Yoshimitsu, Yoshinori Ohashi, Keiji Shiroyama, Nobuyuki Sugioka, Yukako Ito

Publikováno v: Journal of Controlled Release. 121:176-180

To ascertain the pharmacological activity of erythropoietin (EPO) administered by self-dissolving micropiles (SDMP), four kinds of EPO SDMPs were prepared and were administered to rats in 4 consecutive days at 200, 500, 1000 and 2300 IU/kg. After the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5ce56ab6c4e1ec097bb200dfbc4035
https://doi.org/10.1016/j.jconrel.2007.05.028

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Self-dissolving microneedles for the percutaneous absorption of EPO in mice

Autor: Jun-Ichiro Yoshimitsu, Nobuyuki Sugioka, Yukako Ito, Keiji Shiroyama, Kanji Takada

Publikováno v: Journal of Drug Targeting. 14:255-261

Erythropoietin (EPO) loaded microneedles were prepared using thread-forming polymer as a base for the percutaneous administration of EPO. The used polymers were dextrin, chondroitin sulfate and albumin. Under room temperature, EPO solution was added

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2fae108584c34e07b8a23b4c49eded
https://doi.org/10.1080/10611860600785080

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Self-Dissolving Micropiles for the Percutaneous Absorption of Recombinant Human Growth Hormone in Rats

Autor: Yukako Ito, Nobuyuki Sugioka, Keiji Shiroyama, Yoshinori Ohashi, Kanji Takada

Publikováno v: Biological & Pharmaceutical Bulletin. 31:1631-1633

The feasibility of self-dissolving micropiles (SDMP) as a percutaneous delivery system of recombinant human growth hormone (rhGH) has been studied in rats using SDMP where dextran was used as a base. After mixing dextran solution with rhGH, SDMPs wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67a364fa97a03d01ec3c05e4e831857
https://doi.org/10.1248/bpb.31.1631

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