Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Keiji Nakagami"'
1
Molecular Pathology in Atherosclerosis: The Mechanism How Cholesteryl Ester Accumulates in Atheromatous Aorta
Autor: Kimiko Amanuma, Yasuko Yagyu, Hiroyuki Itabe, Keiji Nakagami, Yasuyuki Fujimoto, Tatsuya Takano, Chieko Mineo, Eiko Fujita, Junji Kimura, Yusuke Higashi, Ryoichi Hashita, Masahiro Mori, Ryuichiro Sato, Tsuneo Imanaka
Publikováno v: YAKUGAKU ZASSHI. 128:1383-1401
To study how cholesterol accumulates in atheroma, novel monoclonal antibodies were developed, using crude homogenate of atheroma as immunogens. 212D monoclonal antibody recognizing extra cellular matrix with lipid-laden deposits was selected by histo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341fa6a6908ec2eeb39704c6de6088a3
https://doi.org/10.1248/yakushi.128.1383
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2
Effect of Mizoribine on Effector T Cell-Mediated Immune Responses in Mice
Autor: Hiroyuki Kamada, Naoki Inoue, Keiji Nakagami, Yuko Takaoka, Hiroshi Mori, Hiroichi Nagai
Publikováno v: Biological and Pharmaceutical Bulletin. 19:1136-1140
T cells play a principal role in cellular immunity and govern the regulatory mechanism in humoral immunity. Therefore, T cells play a key role as either effectors or regulators in the immune network. Mizoribine (MZR), an immunosuppressive agent, supp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30171da72d19353d9811388ceb6e870a
https://doi.org/10.1248/bpb.19.1136
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3
Effect of Mizoribine on Collagen-Induced Arthritis in Mice
Autor: Hiroyuki Kamada, Keiji Nakagami
Publikováno v: Japanese Journal of Pharmacology. 70:169-176
This study examines the effect of mizoribine (MZR), an immunosuppressant, on collagen-induced arthritis in mice. DBA/1J mice, immunized on days 0 and 21 with 200 micrograms of type II collagen in complete Freund adjuvant, were treated with various do
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e1977867bfd071777c677d64ecc6b5
https://doi.org/10.1254/jjp.70.169
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4
Antitumor Activity of a Novel Nucleotide Derivative, 5'-(1,2-Dipalmitoyl-sn-glycero-3-phospho)-5-fluorouridine (TJ14026) on Murine Tumors
Autor: Takehiko Koshio, Hiromichi Itoh, Kanki Komiyama, Keiji Nakagami, Masahiko Hayashi
Publikováno v: Biological and Pharmaceutical Bulletin. 16:778-781
The antitumor activity of a nucleotide derivative, 5'-(1,2-dipalmitoyl-sn-glycero-3-phospho)-5-fluorouridine (TJ14026), was confirmed following both intraperitoneal and oral administration against a number of murine experimental tumor systems in vivo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a3255a259389da930711ac8ab520de
https://doi.org/10.1248/bpb.16.778
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5
New Neplanocin Analogues II. Enzymatic One-Step Synthesis and Antitumor Activity of 6′-(3-sn-Phosphatidyl)Neplanocin a Derivatives
Autor: Satoshi Yaginuma, Hiromichi Ito, Akira Matsuda, Tohru Ueda, Tetsu Saito, Takumi Obara, Masatoshi Tsujino, Keiji Nakagami, Masao Yaso, Satoshi Shuto
Publikováno v: Nucleosides and Nucleotides. 11:437-446
A novel series of neplanocin analogues, 6′-(3-sn-phosphatidyl)neplanocin As bearing a variety of fatty acyl or alkyl residues in the glyceride moiety (2b-2h), were synthesized by means of phospholipase D-catalyzed transphosphatidylation. Among them
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bdc0293f67599e26b1769829f8c8d38
https://doi.org/10.1080/07328319208021716
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6
Role of MOG-stimulated Th1 type 'light up' (GFP+) CD4+ T cells for the development of experimental autoimmune encephalomyelitis (EAE)
Autor: Takehiro Koshio, Yoshikazu Yuki, Mamoru Yura, Hiroshi Kiyono, Ichiro Takahashi, Keiji Nakagami, Masashi Serada
Publikováno v: Journal of autoimmunity. 17(1)
Experimental autoimmune encephalomyelitis (EAE) is an animal model for multiple sclerosis in humans. EAE can be passively transferred into naive syngeneic animals by administration of MOG-specific T cell clones. Lymphocytes isolated from green fluore
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f81d3bbf5344336d19202d8f0611cc
https://pubmed.ncbi.nlm.nih.gov/11488634
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8
[Effect of liposome-encapsulated recombinant human superoxide dismutase (liposome-r-h-SOD) on the lung injury induced by Forssman antiserum in guinea pigs]
Autor: Megumi Inamura, Yoshiro Kobayashi, Keiji Nakagami, Yuji Nakano
Publikováno v: Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 97(1)
We investigated the effect of liposome-r-h-SOD on the lung injury induced by Forssman antiserum in guinea pigs. Intravenous injection of Forssman antiserum produced a biphasic increase in pulmonary resistance in guinea pigs. Liposome-r-h-SOD blocked
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e19038ddddf5f1ae6183bddd3d490c5
https://pubmed.ncbi.nlm.nih.gov/2045014
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