Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Keiji Miyazawa"'
Autor:
Mai Koizumi Ichikawa, Kaori Endo, Yuka Itoh, Asami Hotta Osada, Yujiro Kimura, Koichiro Ueki, Kunio Yoshizawa, Keiji Miyazawa, Masao Saitoh
Publikováno v:
FEBS Open Bio, Vol 12, Iss 7, Pp 1353-1364 (2022)
The epithelial–mesenchymal transition (EMT) is a crucial morphological event that occurs during epithelial tumor progression. Snail and ZEB1/2 (ZEB1 and ZEB2), known as EMT transcription factors, are key regulators of this transition. ZEB1/2 are po
Externí odkaz:
https://doaj.org/article/f2b0bc2bb5934b64860dcf24257f6926
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/46a599d064c44f8781b9bf8c8c87e245
Autor:
Kaname Sakamoto, Kaori Endo, Kei Sakamoto, Kou Kayamori, Shogo Ehata, Jiro Ichikawa, Takashi Ando, Ryosuke Nakamura, Yujiro Kimura, Kunio Yoshizawa, Keisuke Masuyama, Tomoyuki Kawataki, Kunio Miyake, Hiroki Ishii, Tomonori Kawasaki, Keiji Miyazawa, Masao Saitoh
Publikováno v:
Oncogenesis, Vol 10, Iss 3, Pp 1-15 (2021)
Abstract ETS homologous factor (EHF) belongs to the epithelium-specific subfamily of the E26 transformation-specific (ETS) transcription factor family. Currently, little is known about EHF’s function in cancer. We previously reported that ETS1 indu
Externí odkaz:
https://doaj.org/article/afa69439fee24eea9cd6fcd85029e401
Autor:
Kei Takahashi, Shogo Ehata, Kensuke Miyauchi, Yasuyuki Morishita, Keiji Miyazawa, Kohei Miyazono
Publikováno v:
Molecular Oncology, Vol 15, Iss 1, Pp 151-166 (2021)
Pancreatic cancer is one of the cancers with the poorest prognosis, with a 5‐year survival rate of approximately 5–10%. Thus, it is urgent to identify molecular targets for the treatment of pancreatic cancer. Using serial transplantations in a mo
Externí odkaz:
https://doaj.org/article/091676d157b44a0986c15194fcfdf41a
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3781-3789 (2019)
Uncovering how new members of multigene families acquire new functions is an important topic in evolutionary and developmental genetics. CORL proteins (SKOR in mice, Fussel in humans and fussel in Flybase) are a family of CNS specific proteins relate
Externí odkaz:
https://doaj.org/article/d46ebd2f722644b98ffabea3c446f256
Autor:
Asami Hotta Osada, Kaori Endo, Yujiro Kimura, Kei Sakamoto, Ryosuke Nakamura, Kaname Sakamoto, Koichiro Ueki, Kunio Yoshizawa, Keiji Miyazawa, Masao Saitoh
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0217451 (2019)
The epithelial-mesenchymal transition (EMT) is a crucial morphological event that occurs during epithelial tumor progression. ZEB1/2 are EMT transcription factors that are positively correlated with EMT phenotypes and breast cancer aggressiveness. ZE
Externí odkaz:
https://doaj.org/article/33bcd9aafef841648fc4883145a1192b
Autor:
Ryosuke Nakamura, Hiroki Ishii, Kaori Endo, Asami Hotta, Eiji Fujii, Keiji Miyazawa, Masao Saitoh
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0199442 (2018)
Snail, also called Snai1, is a key regulator of EMT. Snail plays crucial roles in cancer progression, including resistance to anti-tumor drugs and invasion by various cancer cells. Slug, also known as Snai2, is also involved in the aggravation of cer
Externí odkaz:
https://doaj.org/article/7caf16414c254e5ab3467dbe0fc4f3e8
Autor:
Gregory D Ferguson, Mercedes Delgado, Veronique Plantevin-Krenitsky, Kristen Jensen-Pergakes, R J Bates, Sanaa Torres, Maria Celeridad, Heather Brown, Kelven Burnett, Lisa Nadolny, Lida Tehrani, Garrick Packard, Barbra Pagarigan, Jason Haelewyn, Trish Nguyen, Li Xu, Yang Tang, Matthew Hickman, Frans Baculi, Steven Pierce, Keiji Miyazawa, Pilgrim Jackson, Philip Chamberlain, Laurie LeBrun, Weilin Xie, Brydon Bennett, Kate Blease
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145705 (2016)
Autoantibodies and the immunoreceptors to which they bind can contribute to the pathogenesis of autoimmune diseases such as rheumatoid arthritis (RA). Spleen Tyrosine Kinase (Syk) is a non-receptor tyrosine kinase with a central role in immunorecepto
Externí odkaz:
https://doaj.org/article/500fb09ba236468db438ca0053bf54d2
Autor:
Masao Saitoh, Takuya Shirakihara, Akira Fukasawa, Kana Horiguchi, Kei Sakamoto, Hiroshi Sugiya, Hideyuki Beppu, Yasuyuki Fujita, Ikuo Morita, Kohei Miyazono, Keiji Miyazawa
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62659 (2013)
Bone morphogenetic proteins (BMPs) regulate various biological processes, mostly mediated by cells of mesenchymal origin. However, the roles of BMPs in epithelial cells are poorly understood. Here, we demonstrate that, in polarized epithelial cells,
Externí odkaz:
https://doaj.org/article/1db64911443543c2a54d1ac18884d87e
Publikováno v:
Journal of Biological Chemistry. May2024, Vol. 300 Issue 5, p1-32. 32p.