Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Keiji Masuda"'
Autor:
Ryoji Taira, Satoshi Akamine, Sayaka Okuzono, Fumihiko Fujii, Eriko Hatai, Kousuke Yonemoto, Ryuichi Takemoto, Hiroki Kato, Keiji Masuda, Takahiro A. Kato, Ryutaro Kira, Keita Tsujimura, Kenichiro Yamamura, Norio Ozaki, Shouichi Ohga, Yasunari Sakai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract GNAO1 encodes G protein subunit alpha O1 (Gαo). Pathogenic variations in GNAO1 cause developmental delay, intractable seizures, and progressive involuntary movements from early infancy. Because the functional role of GNAO1 in the developing
Externí odkaz:
https://doaj.org/article/d8d36bc2a350495790ccaae44b9b9ab7
Autor:
Fumihiko Fujii, Hikaru Kanemasa, Sayaka Okuzono, Daiki Setoyama, Ryoji Taira, Kousuke Yonemoto, Yoshitomo Motomura, Hiroki Kato, Keiji Masuda, Takahiro A. Kato, Shouichi Ohga, Yasunari Sakai
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 6 (2024)
Externí odkaz:
https://doaj.org/article/3472d26e58c74f6cb7b572ff8411a0fa
Autor:
Xiao Sun, Jun Kong, Shuangshan Dong, Hiroki Kato, Hiroshi Sato, Yuta Hirofuji, Yosuke Ito, Lu Wang, Takahiro A. Kato, Michiko Torio, Yasunari Sakai, Shouichi Ohga, Satoshi Fukumoto, Keiji Masuda
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 12, Pp 507-520 (2023)
AbstractMutations in the gene encoding the transient receptor potential vanilloid member 4 (TRPV4), a Ca2+ permeable nonselective cation channel, cause TRPV4‐related disorders. TRPV4 is widely expressed in the brain; however, the pathogenesis under
Externí odkaz:
https://doaj.org/article/0cdbe5a4f55047389e8c613fbccc9aa8
Autor:
Noritoshi Shirozu, Masahiro Ohgidani, Nobuhiro Hata, Shunya Tanaka, Shogo Inamine, Noriaki Sagata, Tetsuaki Kimura, Ituro Inoue, Koichi Arimura, Akira Nakamizo, Ataru Nishimura, Naoki Maehara, Soh Takagishi, Katsuma Iwaki, Tomohiro Nakao, Keiji Masuda, Yasunari Sakai, Masahiro Mizoguchi, Koji Yoshimoto, Takahiro A. Kato
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Angiogenic factors associated with Moyamoya disease (MMD) are overexpressed in M2 polarized microglia in ischemic stroke, suggesting that microglia may be involved in the pathophysiology of MMD; however, existing approaches are not applicabl
Externí odkaz:
https://doaj.org/article/cf03e8acbc4144bdad49470e7083ea0b
Publikováno v:
Medicina, Vol 60, Iss 3, p 356 (2024)
Background and Objectives: The conventional posterior approach in the lateral decubitus position is widely used for femoral neck fractures in femoral hemiarthroplasty. Postoperative dislocation is the major problem with this approach. The conjoined t
Externí odkaz:
https://doaj.org/article/f98e97a67a9f4d99af6b4e09177aa543
Autor:
Xiao Sun, Hiroki Kato, Hiroshi Sato, Xu Han, Yuta Hirofuji, Takahiro A. Kato, Yasunari Sakai, Shouichi Ohga, Satoshi Fukumoto, Keiji Masuda
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 7, Pp 454-467 (2022)
Abstract Down syndrome (DS) is one of the common genetic disorders caused by the trisomy of human chromosome 21 (HSA21). Mitochondrial dysfunction and redox imbalance play important roles in DS pathology, and altered dopaminergic regulation has been
Externí odkaz:
https://doaj.org/article/af7dadf862714dad8523cdb726f11d10
Autor:
Noriaki Sagata, Shin‐ichi Kano, Masahiro Ohgidani, Shogo Inamine, Yasunari Sakai, Hiroki Kato, Keiji Masuda, Takeshi Nakahara, Makiko Nakahara‐Kido, Shouichi Ohga, Masutaka Furue, Akira Sawa, Shigenobu Kanba, Takahiro A. Kato
Publikováno v:
Neuropsychopharmacology Reports, Vol 40, Iss 4, Pp 396-400 (2020)
Abstract Aim Neurofibromatosis type 1 (NF1) is a multifaceted disease, and frequently comorbid with neurodevelopmental disorders such as autism spectrum disorder (ASD) and learning disorder. Dysfunction of adenylyl cyclase (AC) is one of the candidat
Externí odkaz:
https://doaj.org/article/ee59a769ea2f4ccfbc0fe75e7c8893c3
Autor:
Xiao Sun, Hiroki Kato, Hiroshi Sato, Michiko Torio, Xu Han, Yu Zhang, Yuta Hirofuji, Takahiro A. Kato, Yasunari Sakai, Shouichi Ohga, Satoshi Fukumoto, Keiji Masuda
Publikováno v:
Biochemistry and Biophysics Reports, Vol 26, Iss , Pp 100968- (2021)
Transient receptor potential vanilloid member 4 (TRPV4) is a Ca2+ permeable nonselective cation channel, and mutations in the TRPV4 gene cause congenital skeletal dysplasias and peripheral neuropathies. Although TRPV4 is widely expressed in the brain
Externí odkaz:
https://doaj.org/article/8edf13f819df42e5a7350896ce8beec5
Autor:
Xu Han, Kentaro Nonaka, Hiroki Kato, Haruyoshi Yamaza, Hiroshi Sato, Takashi Kifune, Yuta Hirofuji, Keiji Masuda
Publikováno v:
Biochemistry and Biophysics Reports, Vol 17, Iss , Pp 32-37 (2019)
Leigh syndrome is a highly heterogeneous condition caused by pathological mutations in either nuclear or mitochondrial DNA regions encoding molecules involved in mitochondrial oxidative phosphorylation, in which many organs including the brain can be
Externí odkaz:
https://doaj.org/article/6461ac839f3c4ef3acb1848c1595c209
Autor:
Xiao Sun, Shuangshan Dong, Hiroki Kato, Jun Kong, Yosuke Ito, Yuta Hirofuji, Hiroshi Sato, Takahiro A. Kato, Yasunari Sakai, Shouichi Ohga, Satoshi Fukumoto, Keiji Masuda
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1361 (2022)
Mitochondrial fission factor (MFF) is an adapter that targets dynamin-related protein 1 from the cytosol to the mitochondria for fission. Loss-of-function MFF mutations cause encephalopathy due to defective mitochondrial and peroxisomal fission 2 (EM
Externí odkaz:
https://doaj.org/article/96e5c42f76be49d58effcdfe280cfb07