Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Keiji Masaki"'
Autor:
Atsuhiro Inaba, Keiji Masaki, Kiyomi Shirakawa, Shin-ichi Ninomiya, Masatoshi Tomida, Yoshio Esumi, Toshiyuki Mashiko, Ryoji Konishi
Publikováno v:
Drug Metabolism and Pharmacokinetics. 11:81-92
The absorption, distribution, metabolism and excretion of MC903 were investigated in rats after a single dermal application in 5 μg/100 mg ointment/body using an occlusive dressing technique. 1. The radioactivity level in the plasma reached a Cmax a
Autor:
Masatoshi Tomida, Atsuhiro Inaba, Toshiyuki Mashiko, Shin-ichi Ninomiya, Ryoji Konishi, Keiji Masaki, Kiyomi Shirakawa, Yoshio Esumi
Publikováno v:
Drug Metabolism and Pharmacokinetics. 11:57-80
The absorption, distribution, metabolism, excretion, transfer into the fetus and milk of MC903 were investigated in rats after a single subcutaneous administration (2 μg/kg). 1. The level of radioactivity in the plasma reached a Cmax at 1 hr, the re
Autor:
Masatoshi Tomida, Atsuhiro Inaba, Shin-ichi Ninomiya, Ryoji Konishi, Keiji Masaki, Kiyomi Shirakawa, Yoshio Esumi, Toshiyuki Mashiko
Publikováno v:
Drug Metabolism and Pharmacokinetics. 11:93-105
Autor:
Koichi Oka, Keiji Masaki
Publikováno v:
The proceedings of the JSME annual meeting. :233-234
Autor:
Keiji Masaki, Koichi Oka
Publikováno v:
The Proceedings of Conference of Chugoku-Shikoku Branch. :343-344
Autor:
Takeru Higuchi, Tomoo Itoh, Ba Thu Nghiem, R. Konishi, Mitsuji Akazawa, Noriko Tsuzuki, Keiji Masaki
Publikováno v:
International Journal of Pharmaceutics. 50:53-60
A fully automated system for studying in vitro skin penetration has been developed. In the present system, frequent monitoring of drug transport through a membrane in a diffusion cell provides for the accurate measurement of steady-state flux and lag
Autor:
Takeru Higuchi, J. Huntington, T. Itoh, J. Kuehnhoff, Ba Thu Nghiem, Noriko Tsuzuki, Keiji Masaki, J.H. Rytting, Ooi Wong, R. Konishi
Publikováno v:
International Journal of Pharmaceutics. 52:191-202
Thirteen new transdermal penetration enhancers were evaluated with respect to the absorption of indomethacin using shed snake skin of Elaphe obsoleta as a model of the stratum corneum and using Azone as the standard enhancer for comparison. Indometha
Autor:
Kazuo Kushida, Kanji Takada, Hiroshi Yoshikawa, Taeyuki Ohshima, Keiji Masaki, Masayoshi Matsumura, Shozo Muranishi
Publikováno v:
Chemicalpharmaceutical bulletin. 32(1)
To improve drug penetration through the skin, we studied the effect of calcium thioglycolate (Ca-TGA) on the percutaneous absorption of theophylline in comparison with the promoting effects of dimethylsulfoxide (DMSO) and polyoxyethylenelaurylether (