Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Keiji Kondoh"'
Publikováno v:
Journal of Neurochemistry. 59:2012-2016
A sensitive and specific method for determining three forms of methylarginine, i.e., NG-monomethylarginine, NG,NG-dimethylarginine, and NG,NG-dimethylarginine, in mammalian tissues was developed. After partial purification by ion-exchange chromatogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05cc289cacde55da2b5c59ae9d65625
https://doi.org/10.1111/j.1471-4159.1992.tb10088.x
https://doi.org/10.1111/j.1471-4159.1992.tb10088.x
Autor:
H Mitsushio, Hiroki Ishiguro, Keiji Kondoh, Masaaki Mikami, T Komiyama, Shu-ichi Ueno, Akira Sano, Tadao Arinami, Masayuki Nakamura, Hirotaka Tanabe
Publikováno v:
Molecular Psychiatry. 4:552-557
Human dopamine transporter gene (DAT1) has a variable number of tandem repeats (VNTR) in its 3'-untranslated region (UTR). The association between the VNTR polymorphism and neuropsychiatric disorders has been studied, but their relationship is still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99151aafacdefc0656348e9107abbe38
https://doi.org/10.1038/sj.mp.4000562
https://doi.org/10.1038/sj.mp.4000562
Autor:
Xiaoyang Qi, Tatyana Leonova, Keiji Kondoh, Gregory J. Kelso, Gregory A. Grabowski, David Krusling
Publikováno v:
Biochemistry. 38:6284-6291
Prosaposin is the precursor of four activator proteins, termed saposins A, B, C, and D, that are required for much of glycosphingolipid hydrolysis. The intact precursor also has neurite outgrowth activity ex vivo and in vivo that is localized to amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff342a51706eddc05b628a659d8dbdd
https://doi.org/10.1021/bi990079o
https://doi.org/10.1021/bi990079o
Publikováno v:
Journal of Biological Chemistry. 271:6874-6880
Saposin C is an essential co-factor for the hydrolysis of glucosylceramide by acid β-glucosidase in mammals. In addition, prosaposin promotes neurite outgrowth in vitro via sequences in saposin C. The regional organization of these neurotrophic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d4b9350b2878c114ad54b1a033c9e11
https://doi.org/10.1074/jbc.271.12.6874
https://doi.org/10.1074/jbc.271.12.6874
Autor:
Keiji Kondoh, Akira Sano, Osamu Komure, Yasunori Kotani, F. Hazama, Shu-ichi Ueno, J. Kawai, S. Kuno
Publikováno v:
Human Molecular Genetics. 4:663-666
An unstable expansion of CAG repeat in the coding region of the DRPLA gene on chromosome 12p is the mutation specific for hereditary dentatorubral-pallidoluysian atrophy (DRPLA). We studied the CAG expansion in brain and other tissues from six unrela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd4f2e8881b13e468bc6be51724107e
https://doi.org/10.1093/hmg/4.4.663
https://doi.org/10.1093/hmg/4.4.663
Autor:
Akira Sano, Anthony T. Campagnoni, Yasunori Kotani, Keiji Kondoh, Shu-ichi Ueno, Yasuo Kakimoto
Publikováno v:
Biochemical and Biophysical Research Communications. 204:1352-1357
The 3'-untranslated region (UTR) of the myelin basic protein (MBP) mRNA has been found previously to enhance the translational efficiency of the coding region by two-fold in cell-free translational systems. In this study, we transfected eukaryotic ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079c90cd02193b3d8a301c740d957b8a
https://doi.org/10.1006/bbrc.1994.2612
https://doi.org/10.1006/bbrc.1994.2612
Publikováno v:
Biochemical and Biophysical Research Communications. 181:286-292
Prosaposin is the precursor protein for saposins, which are small lysosomal proteins required for the hydrolysis of sphingolipids by specific lysosomal hydrolases. Prosaposin, in addition to generating the saposins in the lysosomes, also exists as an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bea02225f742c1520a964f0ee589741
https://doi.org/10.1016/s0006-291x(05)81415-9
https://doi.org/10.1016/s0006-291x(05)81415-9
Publikováno v:
Biochemical and Biophysical Research Communications. 176:668-674
Sphingolipid hydrolases are activated by activator proteins or saposins. The precursor protein has been expected from the studies on the cDNA for saposins. Here we demonstrate that prosaposin occurs in various kinds of human secretory fluids such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b221c51385b4acea6701b438f6b6972a
https://doi.org/10.1016/s0006-291x(05)80236-0
https://doi.org/10.1016/s0006-291x(05)80236-0
Autor:
David P. Witte, Brian Quinn, Gregory A. Grabowski, Xiaoyang Qi, Ying Sun, Keiji Kondoh, Elvira Ponce
Publikováno v:
Molecular genetics and metabolism. 76(4)
Prosaposin is the precursor of four glycoprotein activators (saposins) for lysosomal hydrolases. Intact prosaposin also has lipid transfer properties in vitro as well as neuritogenic effects ex vivo and in vivo. Such “neuritogenic” effects of sap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88ab971c321b868800ff196486c4a5f
https://pubmed.ncbi.nlm.nih.gov/12208132
https://pubmed.ncbi.nlm.nih.gov/12208132
Autor:
Kazuko Koshiro, Koichi Otani, Shu-ichi Ueno, Yasunori Kotani, Keiji Kondoh, Akira Sano, Sunao Kaneko
Publikováno v:
Biological psychiatry. 40(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989f2e9f0775c657120b31f3d674f821
https://pubmed.ncbi.nlm.nih.gov/8780858
https://pubmed.ncbi.nlm.nih.gov/8780858