Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Keiji Ibata"'
Autor:
Sho Wakayama, Shigeki Kiyonaka, Itaru Arai, Wataru Kakegawa, Shinji Matsuda, Keiji Ibata, Yuri L. Nemoto, Akihiro Kusumi, Michisuke Yuzaki, Itaru Hamachi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Visualizing neurotransmitter receptor traffic is fundamental to understanding brain functions, but the current imaging methods can compromise the process. Here, the authors synthesize small fluorescent probes to label endogenous glutamate receptors i
Externí odkaz:
https://doaj.org/article/7eea3380bd2546d2924bb2c3f664fc62
Autor:
Kent Imaizumi, Takefumi Sone, Keiji Ibata, Koki Fujimori, Michisuke Yuzaki, Wado Akamatsu, Hideyuki Okano
Publikováno v:
Stem Cell Reports, Vol 5, Iss 6, Pp 1010-1022 (2015)
The CNS contains many diverse neuronal subtypes, and most neurological diseases target specific subtypes. However, the mechanism of neuronal subtype specificity of disease phenotypes remains elusive. Although in vitro disease models employing human p
Externí odkaz:
https://doaj.org/article/017ab55e645247f1ad1c89fb88e77c2f
Autor:
Hiroko Shimada, Yohei Okada, Keiji Ibata, Hayao Ebise, Shin-ichi Ota, Ikuo Tomioka, Toshihiro Nomura, Takuji Maeda, Kazuhisa Kohda, Michisuke Yuzaki, Erika Sasaki, Masaya Nakamura, Hideyuki Okano
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49469 (2012)
The common marmoset (Callithrix jacchus) is a small New World primate that has been used as a non-human primate model for various biomedical studies. We previously demonstrated that transplantation of neural stem/progenitor cells (NS/PCs) derived fro
Externí odkaz:
https://doaj.org/article/81ea037bc14746c29b9ca37f8a508fb8
Autor:
Keiji Ibata, Michisuke Yuzaki
Publikováno v:
Neuroscience research. 167
Lysosomes are organelles that support diverse cellular functions such as terminal degradation of macromolecules and nutrient recycling. Additionally, lysosomes can fuse with the plasma membrane, a phenomenon referred to as lysosomal exocytosis, to re
Autor:
Jin Nakahara, Mamoru Shibata, Toshihiko Shimizu, Norihiro Suzuki, Tsubasa Takizawa, Michisuke Yuzaki, Keiji Ibata, Yohei Kayama
Publikováno v:
Molecular Pain
Capsaicin is an agonist of transient receptor potential cation channel subfamily V member 1 (TRPV1). Strong TRPV1 stimulation with capsaicin causes mitochondrial damage in primary sensory neurons. However, the effect of repetitive and moderate exposu
Autor:
Akash Pal, Ryan Welchko, Atsushi Miyawaki, Gabrielle P. Shall, Eric D. Petersen, Sang-Ho Song, George J. Augustine, Keiji Ibata, Brandon Palmateer, Sung Young Park, Ute Hochgeschwender
Publikováno v:
Journal of Neuroscience Research. 98:410-421
Previous work has demonstrated that fusion of a luciferase to an opsin, to create a luminescent opsin or luminopsin, provides a genetically encoded means of manipulating neuronal activity via both chemogenetic and optogenetic approaches. Here we have
Autor:
Keiji Ibata, Wado Akamatsu, Takefumi Sone, Koki Fujimori, Michisuke Yuzaki, Kent Imaizumi, Hideyuki Okano
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 5, Iss 6, Pp 1010-1022 (2015)
Stem Cell Reports, Vol 5, Iss 6, Pp 1010-1022 (2015)
Summary The CNS contains many diverse neuronal subtypes, and most neurological diseases target specific subtypes. However, the mechanism of neuronal subtype specificity of disease phenotypes remains elusive. Although in vitro disease models employing
Autor:
Jin Nakahara, Mamoru Shibata, Norihiro Suzuki, Haruki Toriumi, Michisuke Yuzaki, Keiji Ibata, Yohei Kayama, Toshihiko Shimizu, Tsubasa Takizawa
Publikováno v:
Neuroscience. 367
Transient receptor potential melastatin 8 (TRPM8) is a nonselective cation channel that primarily detects the innocuous cold. In pathological conditions, TRPM8 plays a role in the development of cold hyperalgesia/allodynia. Nerve growth factor (NGF)
Autor:
Tsubasa Takizawa, Norihiro Suzuki, Yohei Kayama, Mamoru Shibata, Haruki Toriumi, Michisuke Yuzaki, Taeko Ebine, Toshihiko Shimizu, Keiji Ibata
Publikováno v:
Cephalalgia : an international journal of headache. 38(5)
Background Recent genome-wide association studies have identified transient receptor potential M8 ( TRPM8) as a migraine susceptibility gene. TRPM8 is a nonselective cation channel that mediates cool perception. However, its precise role in migraine
Autor:
Yuri L. Nemoto, Michisuke Yuzaki, Keiji Ibata, Itaru Hamachi, Shigeki Kiyonaka, Shinji Matsuda, Akihiro Kusumi, Itaru Arai, Sho Wakayama, Wataru Kakegawa
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The location and number of neurotransmitter receptors are dynamically regulated at postsynaptic sites. However, currently available methods for visualizing receptor trafficking require the introduction of genetically engineered receptors into neurons