Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Keiji Fujioka"'
Autor:
Seiji Shirai, Keiji Fujioka, Kunio Saki, Kenji Fujita, Fumiharu Takahashi, Fumitaka Kikkawa, Akihiro Sakanishi, Yuji Yamamoto, Akihiko Yano, Yukihiro Uchida, Tsuyoshi Kawazoe
Publikováno v:
Tribology Transactions. 50:13-24
The previous report described corrosive wear of propeller shaft sleeves made of bronze in seawater-lubricated stern tube bearings, as well as the occurrence of craters on the sleeve surface due to the action of erosion corrosion. Based on the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd723a148ab8820ce3d43ea368e8d360
https://doi.org/10.1080/10402000600927944
https://doi.org/10.1080/10402000600927944
Autor:
Seiji Shirai, Kunio Saki, Akihiko Yano, Yuji Yamamoto, Keiji Fujioka, Akihiro Sakanishi, Fumitaka Kikkawa, Kenji Fujita, Yoshiaki Hirayama, Yukihiro Uchida, Tsuyoshi Kawazoe
Publikováno v:
Tribology Transactions. 50:1-12
As propeller shaft diameters of ferries become larger in conjunction with higher vessel speed and equipping with CPPs (controllable pitch propellers), the life duration of a stern tube bearing under seawater lubrication has a tendency to be reduced.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f98fd7c384a044bd6cb9ac48edcf1465
https://doi.org/10.1080/10402000600927928
https://doi.org/10.1080/10402000600927928
Autor:
Akihiko Sano, Hiroshi Itoh, Keiji Fujioka, Kimi Honma, Takahiro Ochiya, Miho Maeda, Shunji Nagahara, Teruo Miyata
Publikováno v:
Advanced Drug Delivery Reviews. 55:1651-1677
Recent progress in recombinant gene technology and cell culture technology has made it possible to use protein and polynucleotides as effective drugs. However, because of their short half-lives in the body and the necessity of delivering to target si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e331a3c9090021c85712488894d02781
https://doi.org/10.1016/j.addr.2003.08.005
https://doi.org/10.1016/j.addr.2003.08.005
Autor:
Tomonaga Yamamoto, Keiji Fujioka, Hiroo Maeda, Noriyuki Adachi, Teruo Miyata, Akio Matsuoka, Akihiko Sano, Takashi Nakagawa, Yasuyuki Sakai, Yukihiro Satoh
Publikováno v:
Journal of Controlled Release. 91:281-297
In order to design a sustained-release formulation of protein drugs characterized by excellent long-acting properties without an initial burst, a new double-layer minipellet (DL-MP) in which the lateral side of a matrix-type sustained-release formula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8106924cb9d7c4239797b05d8a9c40
https://doi.org/10.1016/s0168-3659(03)00247-5
https://doi.org/10.1016/s0168-3659(03)00247-5
Autor:
Toshihiko Sugie, Keiji Fujioka, Masako Kajihara, Masao Tanihara, Yosuke Urabe, Yukio Imanishi, Akihiko Sano
Publikováno v:
Chemical and Pharmaceutical Bulletin. 51:11-14
Silicone has been utilized as a carrier material for sustained release system of lipophilic drugs. Extensive studies revealed that drug release rate is influenced by factors such as physicochemical properties of the drug and additives.(1-5)) When a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52f03883969500c5f994f96230ab5a7
https://doi.org/10.1248/cpb.51.11
https://doi.org/10.1248/cpb.51.11
Publikováno v:
Journal of Controlled Release. 77:261-272
Collagen films containing human growth hormone (hGH) were prepared and the release of hGH from these films and their effect on healing of full-thickness wounds in db/db mice were evaluated. The release profiles of hGH from the collagen films varied w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f366fba0bf061ab4927680ca279774d
https://doi.org/10.1016/s0168-3659(01)00512-0
https://doi.org/10.1016/s0168-3659(01)00512-0
Publikováno v:
Advanced Drug Delivery Reviews. 31:247-266
The effective delivery of protein drugs is an important research subject in the field of pharmacology, and to prolong the effect of protein drugs, many studies are being conducted to control the release of proteins from various carrier materials. Col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9407e4abcf090563c11692d197b461
https://doi.org/10.1016/s0169-409x(97)00119-1
https://doi.org/10.1016/s0169-409x(97)00119-1
Autor:
Kyoko Yamashita, Minoru Nakano, Akihiko Sano, Takeshi Hirasawa, Keiji Fujioka, Kaoru Inoue, Taro Hayakawa, Kaori Miyata
Publikováno v:
Biomedical Research. 18:149-159
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97ed19817c36527f3f69fcfa29704154
https://doi.org/10.2220/biomedres.18.149
https://doi.org/10.2220/biomedres.18.149
Publikováno v:
Journal of Controlled Release. 33:307-315
It is critical to develop effective delivery systems for biologically active peptides and proteins since most of them are rapidly destroyed by the body. In this study, interferon (IFN) was used as a model protein drug and matrix type formulations wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20b5cb57807d3b8a77729f21aa749303
https://doi.org/10.1016/0168-3659(94)00107-6
https://doi.org/10.1016/0168-3659(94)00107-6
Publikováno v:
Journal of Controlled Release. 33:317-323
The optimal composition for an interferon (IFN) minipellet which released IFN with a high bioavailability and a long half-life was designed. Minipellets are cylindrical solid dosage forms using collagen as a biodegradable carrier material. A monolith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08fa3672f56632413aa76bfa3500efcb
https://doi.org/10.1016/0168-3659(94)00106-5
https://doi.org/10.1016/0168-3659(94)00106-5