Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Keiichi Ohya"'
Autor:
Sri Angky Soekanto, Keiichi Ohya
Publikováno v:
Journal of Dentistry Indonesia, Vol 6, Iss 1, Pp 6-11 (2015)
Bisphosphonates are reported to have an inhibitory effect on bone resorption in vivo and in vitro. The present study examined the effect of bisphosphonate on the formation of osteoclast-like cells in vitro. When mouse bone marrow cells were cultured
Externí odkaz:
https://doaj.org/article/fd9acb79deb045f3b79ff26d08fc458c
Autor:
Michio Muguruma, Abdulatef Mrghni Ahhmed, Satoshi Kawahara, Kazuhiro Kusumegi, Tsuyoshi Hishinuma, Keiichi Ohya, Toyoo Nakamura
Publikováno v:
Journal of Functional Foods, Vol 4, Iss 4, Pp 810-818 (2012)
The potential application and nutritional advantages of milky miso (MM) as a functional food were investigated. MM is a mixture of miso, a traditional, fermented soy paste, and skimmed milk. The data suggested that the total and free amino acids were
Externí odkaz:
https://doaj.org/article/7a3436073a484a75b8940c2424d25ea0
Autor:
Mayurach Samee, Shohei Kasugai, Hisatomo Kondo, Keiichi Ohya, Hitoyata Shimokawa, Shinji Kuroda
Publikováno v:
Journal of Pharmacological Sciences, Vol 108, Iss 1, Pp 18-31 (2008)
Periosteum has been demonstrated to contain mesenchymal progenitor cells differentiating to osteoblasts, and both bone morphogenetic protein-2 (BMP-2) and vascular endothelial growth factor (VEGF) may play important roles in cell-based approaches to
Externí odkaz:
https://doaj.org/article/5fd1ee2cdf174530af59168609eaec6c
Publikováno v:
Journal of Pharmacological Sciences, Vol 97, Iss 2, Pp 227-233 (2005)
In vivo gene transfer with plasmid vector has been applied experimentally and clinically; however, the low level of gene transfer efficiency with plasmid vector is a problem. We speculated that the combination of calcium phosphate precipitate (CaP) a
Externí odkaz:
https://doaj.org/article/d11f878bf2eb4db1b5aa4f253b905ec6
Publikováno v:
Journal of Pharmacological Sciences, Vol 98, Iss 3, Pp 290-297 (2005)
It is well-known that the anticonvulsant drug, phenytoin (PHT), induces gingival overgrowth as a side effect. The mechanism of PHT-induced gingival overgrowth, however, is not well understood. One reason for this is the lack of an adequate animal mod
Externí odkaz:
https://doaj.org/article/f022406d46b44fd6bf33135bd9aeb8f7
Autor:
Shinji Kuroda, Nobuhiro Goto, Michiko Suzuki, Kazutaka Kaneda, Keiichi Ohya, Hitoyata Shimokawa, Shohei Kasugai
Publikováno v:
Journal of Tissue Engineering, Vol 1, Iss 1 (2010)
Members of the bone morphogenetic protein (BMP) family have diverse physiological roles. For instance, BMP-2 stimulates osteogenesis, while BMP-12 induces the formation of tendon/ligament-like tissues. Here, we designed a study to determine whethe
Externí odkaz:
https://doaj.org/article/f90d4c6863824691b4c378e2de020dde
Autor:
Kou Matsuo, Masato Okamoto, Yukiyo Tada, Hidefumi Fukushima, Yasutaka Sugamori, Kazuhiro Aoki, Chihiro Nakatomi, Tomoyuki Fujikawa, Akiko Itai, Keiichi Ohya, Osawa Kenji, Eijiro Jimi, Shoichiro Kokabu, Goro Sugiyama, Seiji Watanabe
Publikováno v:
Scopus-Elsevier
Oncotarget
Oncotarget
// Yukiyo Tada 1,2 , Shoichiro Kokabu 1 , Goro Sugiyama 1 , Chihiro Nakatomi 1 , Kazuhiro Aoki 3 , Hidefumi Fukushima 4 , Kenji Osawa 5 , Yasutaka Sugamori 3 , Keiichi Ohya 3 , Masato Okamoto 6 , Tomoyuki Fujikawa 7 , Akiko Itai 7 , Kou Matsuo 8 , Se
Publikováno v:
Tetrahedron. 70:7774-7779
We demonstrate that disulfide bond replacement is an efficient strategy for engineering therapeutic peptides. In previous work, short peptide fragments, known as WP9QY, with sequence homology with the predicted ligand contact surface of the receptor
Autor:
Yukihiko Tamura, Hitoyata Shimokawa, Masayuki Otsuki, Junji Tagami, Shohei Kasugai, Mohannad Nassar, Noriko Hiraishi, Keiichi Ohya
Publikováno v:
Journal of Dentistry. 42:312-318
Objectives Phosphoric acid (PA) etching used in etch-and-rinse adhesives is known to activate host-derived dentinal matrix-metalloproteinases (MMPs) and increase dentinal permeability. These two phenomena will result, respectively; in degradation of
Autor:
Kazuhiro Aoki, Wannakorn Sriarj, Mariko Takahashi, Yuzo Takagi, Hitoyata Shimokawa, Keiichi Ohya
Publikováno v:
Odontology. 103:9-18
Previously, we have demonstrated that the extracellular matrix from dentin affects osteoclastic activity in co-culture between osteoclast and osteoblast-rich fraction from mouse marrow cells. In the present study, we aimed to investigate the mechanis