Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Keiichi Hishikawa"'
Autor:
Taro Tsujimura, Osamu Takase, Masahiro Yoshikawa, Etsuko Sano, Matsuhiko Hayashi, Kazuto Hoshi, Tsuyoshi Takato, Atsushi Toyoda, Hideyuki Okano, Keiichi Hishikawa
Publikováno v:
eLife, Vol 9 (2020)
While regulation of gene-enhancer interaction is intensively studied, its application remains limited. Here, we reconstituted arrays of CTCF-binding sites and devised a synthetic topological insulator with tetO for chromatin-engineering (STITCH). By
Externí odkaz:
https://doaj.org/article/e842a9a8a27747c1b1211b39efd6f45f
Autor:
Taro Tsujimura, Osamu Takase, Masahiro Yoshikawa, Etsuko Sano, Matsuhiko Hayashi, Tsuyoshi Takato, Atsushi Toyoda, Hideyuki Okano, Keiichi Hishikawa
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-17 (2018)
Abstract Background Contact domains of chromatin serve as a fundamental unit to regulate action of enhancers for target genes. Looping between a pair of CCCTC-binding factor (CTCF)-binding sites in convergent orientations underlies the formation of c
Externí odkaz:
https://doaj.org/article/21d3e1b888ca4dc0b086557c206f7e6d
Autor:
Koshu Okubo, Mako Kamiya, Yasuteru Urano, Hiroshi Nishi, Jan M. Herter, Tanya Mayadas, Daigoro Hirohama, Kazuo Suzuki, Hiroshi Kawakami, Mototsugu Tanaka, Miho Kurosawa, Shinji Kagaya, Keiichi Hishikawa, Masaomi Nangaku, Toshiro Fujita, Matsuhiko Hayashi, Junichi Hirahashi
Publikováno v:
EBioMedicine, Vol 10, Iss C, Pp 204-215 (2016)
Neutrophils are central players in the innate immune system. They generate neutrophil extracellular traps (NETs), which protect against invading pathogens but are also associated with the development of autoimmune and/or inflammatory diseases and thr
Externí odkaz:
https://doaj.org/article/e0ab3864351b42569f8d92f288f0f789
Autor:
Osamu Takase, Masahiro Yoshikawa, Mana Idei, Junichi Hirahashi, Toshiro Fujita, Tsuyoshi Takato, Takayuki Isagawa, Genta Nagae, Hirofumi Suemori, Hiroyuki Aburatani, Keiichi Hishikawa
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56399 (2013)
NF-κB signaling plays an essential role in maintaining the undifferentiated state of embryonic stem (ES) cells. However, opposing roles of NF-κB have been reported in mouse and human ES cells, and the role of NF-κB in human induced pluripotent ste
Externí odkaz:
https://doaj.org/article/14c64e79d436496591bf9bd6022fbc1e
Autor:
Toshihiko Inowa, Keiichi Hishikawa, Yumi Matsuzaki, Takayuki Isagawa, Takumi Takeuchi, Hiroyuki Aburatani, Tadaichi Kitamura, Toshiro Fujita
Publikováno v:
Stem Cells International, Vol 2010 (2010)
Side population (SP) cells are an enriched population of stem, and the existence of SP cells has been reported in human cancer cell lines. In this study, we performed an SP analysis using 11 human cancer cell lines and confirmed the presence of SP ce
Externí odkaz:
https://doaj.org/article/5ca7d53499104ef6bca59503afecc9dd
Autor:
Tsuyoshi Takato, Taro Tsujimura, Matsuhiko Hayashi, Keiichi Hishikawa, Masahiro Yoshikawa, Etsuko Sano, Osamu Takase
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Scientific Reports
Scientific Reports
Hypercalcemia and hyperparathyroidism in patients receiving maintenance hemodialysis (MHD) can cause the progression of cardiovascular diseases (CVD) and mineral bone disorders (MBD). The KDIGO recommends the dialysates with a calcium (Ca) concentrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da8303be0a132b80b2ef818fe9c9852
http://link.springer.com/article/10.1038/s41598-018-23658-y
http://link.springer.com/article/10.1038/s41598-018-23658-y
Autor:
Osamu Takase, Tsuyoshi Takato, Hideyuki Okano, Kazuto Hoshi, Taro Tsujimura, Masahiro Yoshikawa, Atsushi Toyoda, Keiichi Hishikawa, Etsuko Sano, Matsuhiko Hayashi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::429e5e6fc8bd36c100eafe9c92252c87
https://doi.org/10.7554/elife.47980.sa2
https://doi.org/10.7554/elife.47980.sa2
Autor:
Masahiro Yoshikawa, Osamu Takase, Hideyuki Okano, Keiichi Hishikawa, Taro Tsujimura, Etsuko Sano, Atsushi Toyoda, Kazuto Hoshi, Tsuyoshi Takato, Matsuhiko Hayashi
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
While regulation of gene-enhancer interaction is better understood, its application remains limited. Here, we reconstituted arrays of CTCF binding sites and devised a synthetic topological insulator with tetO for chromatin-engineering (STITCH). By co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034a7dea1487952feeaa17087c748fee
https://pubmed.ncbi.nlm.nih.gov/32369019
https://pubmed.ncbi.nlm.nih.gov/32369019
Autor:
Mako Kamiya, Matsuhiko Hayashi, Miho Kurosawa, Mototsugu Tanaka, Toshiro Fujita, Junichi Hirahashi, Hiroshi Nishi, Tanya N. Mayadas, Keiichi Hishikawa, Hiroshi Kawakami, Masaomi Nangaku, Yasuteru Urano, Daigoro Hirohama, Jan M. Herter, Kazuo Suzuki, Koshu Okubo, Shinji Kagaya
Publikováno v:
EBioMedicine, Vol 10, Iss C, Pp 204-215 (2016)
EBioMedicine
EBioMedicine
Neutrophils are central players in the innate immune system. They generate neutrophil extracellular traps (NETs), which protect against invading pathogens but are also associated with the development of autoimmune and/or inflammatory diseases and thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52822e5a9b53b8c59452b622678c8780
http://www.sciencedirect.com/science/article/pii/S2352396416303176
http://www.sciencedirect.com/science/article/pii/S2352396416303176
Autor:
Masahiro Yoshikawa, Matsuhiko Hayashi, Hideyuki Okano, Tsuyoshi Takato, Taro Tsujimura, Atsushi Toyoda, Keiichi Hishikawa, Osamu Takase, Etsuko Sano
Publikováno v:
Epigenetics & Chromatin
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-17 (2018)
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-17 (2018)
Background Contact domains of chromatin serve as a fundamental unit to regulate action of enhancers for target genes. Looping between a pair of CCCTC-binding factor (CTCF)-binding sites in convergent orientations underlies the formation of contact do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b726f0462944ecb7886ab9ee70101d
http://europepmc.org/articles/PMC6137755
http://europepmc.org/articles/PMC6137755