Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Keiichi Asano"'
Autor:
Yifei Sun, Keiichi Asano, Lauriane Sedes, Anna Cantalupo, Jens Hansen, Ravi Iyengar, Martin J. Walsh, Francesco Ramirez
Publikováno v:
JCI Insight, Vol 8, Iss 10 (2023)
To improve our limited understanding of the pathogenesis of thoracic aortic aneurysm (TAA) that leads to acute aortic dissection, single-cell RNA sequencing (scRNA-seq) was employed to profile disease-relevant transcriptomic changes of aortic cell po
Externí odkaz:
https://doaj.org/article/d24fa62ce763489b9e21a6996b4faee9
Publikováno v:
Biomolecules, Vol 12, Iss 1, p 128 (2022)
About 20% of individuals afflicted with thoracic aortic disease have single-gene mutations that predispose the vessel to aneurysm formation and/or acute aortic dissection often without associated syndromic features. One widely studied exception is Ma
Externí odkaz:
https://doaj.org/article/7b09de9343b048efa754861bc7738b09
Autor:
Lauriane Sedes, Elisa Wondimu, Brittany Crockett, Jens Hansen, Anna Cantalupo, Keiichi Asano, Ravi Iyengar, Daniel B Rifkin, Silvia Smaldone, Francesco Ramirez
Publikováno v:
Hum Mol Genet
A disproportionate tall stature is the most evident manifestation in Marfan syndrome (MFS), a multisystem condition caused by mutations in the extracellular protein and TGFβ modulator, fibrillin-1. Unlike cardiovascular manifestations, there has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560d1324d25de6ac561b62fe4d391112
https://doi.org/10.1093/hmg/ddac107
https://doi.org/10.1093/hmg/ddac107
Autor:
Anna Cantalupo, Keiichi Asano, Jens Hansen, Carmen Halabi, Robert Mecham, Ravi Iyengar, Francesco Ramirez
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62ac074885b597a5c06634cdcd09de66
https://doi.org/10.1096/fasebj.2022.36.s1.r5672
https://doi.org/10.1096/fasebj.2022.36.s1.r5672
Autor:
Keiichi Asano, Anna Cantalupo, Jens Hansen, Bart Spronck, Jay D. Humphrey, Ravi Iyengar, Francesco Ramirez
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0b63584025eb0682a7be33989509179
https://doi.org/10.1096/fasebj.2022.36.s1.r5562
https://doi.org/10.1096/fasebj.2022.36.s1.r5562
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1892, p 1892 (2022)
Fibrillin-1 is the major structural component of the 10 nm-diameter microfibrils that confer key physical and mechanical properties to virtually every tissue, alone and together with elastin in the elastic fibers. Mutations in fibrillin-1 cause pleio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a499da410b3451a7c7579d3bd51fc445
https://www.mdpi.com/1422-0067/23/3/1892
https://www.mdpi.com/1422-0067/23/3/1892
Autor:
Akira Shinaoka, Toshitaka Oohashi, Mehmet Zeynel Cilek, Satoshi Hirohata, Omer Faruk Hatipoglu, Keiichiro Nishida, Keiichi Asano, Kanae Kumagishi-Shinaoka, Junko Inagaki, Issei Komatsubara, Takashi Ohtsuki
Publikováno v:
Journal of Orthopaedic Research®. 36:3247-3255
Hyaluronan (HA) is an extracellular matrix (ECM) component of articular cartilage and has been used to treat patients with osteoarthritis (OA). A disintegrin and metalloproteinases with thrombospondin motifs (ADAMTSs) play an important role in cartil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c94ae4c00435f90516088867e246ff7
https://doi.org/10.1002/jor.24126
https://doi.org/10.1002/jor.24126
Autor:
Keiichi Asano, Satoshi Hirohata, Junko Inagaki, Takashi Ohtsuki, Keiichiro Nishida, Omer Faruk Hatipoglu
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 9
International Journal of Molecular Sciences, Vol 21, Iss 3140, p 3140 (2020)
Volume 21
Issue 9
International Journal of Molecular Sciences, Vol 21, Iss 3140, p 3140 (2020)
In patients with osteoarthritis (OA), there is a decrease in both the concentration and molecular size of hyaluronan (HA) in the synovial fluid and cartilage. Cell migration-inducing hyaluronidase 1 (CEMIP), also known as hyaluronan (HA)-binding prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1930d87e56182876319f98f5b4ba880
https://ousar.lib.okayama-u.ac.jp/59917
https://ousar.lib.okayama-u.ac.jp/59917
Autor:
Junko Inagaki, Daniel J. Lindner, Satoshi Hirohata, Keiichi Asano, Toshitaka Oohashi, Noriko Aramaki-Hattori, Tyler J. Alban, Sumeda Nandadasa, Takashi Ohtsuki, Suneel S. Apte, Courtney M. Nelson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
The proteoglycan versican is implicated in growth and metastases of several cancers. Here we investigated a potential contribution of stromal versican to tumor growth and angiogenesis. We initially determined versican expression by several cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0510e09aa09947efba512057049550fe
https://doi.org/10.1038/s41598-017-17613-6
https://doi.org/10.1038/s41598-017-17613-6
Autor:
Takashi, Ohtsuki, Keiichi, Asano, Junko, Inagaki, Akira, Shinaoka, Kanae, Kumagishi-Shinaoka, Mehmet Z, Cilek, Omer F, Hatipoglu, Toshitaka, Oohashi, Keiichiro, Nishida, Issei, Komatsubara, Satoshi, Hirohata
Publikováno v:
Journal of Orthopaedic Research
Hyaluronan (HA) is an extracellular matrix (ECM) component of articular cartilage and has been used to treat patients with osteoarthritis (OA). A disintegrin and metalloproteinases with thrombospondin motifs (ADAMTSs) play an important role in cartil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4c5d1afe974c7bf5b1ace2bef917993
https://pubmed.ncbi.nlm.nih.gov/30117186
https://pubmed.ncbi.nlm.nih.gov/30117186