Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Keigo Kohara"'
Autor:
Keigo Kohara, Masayoshi Okada
Publikováno v:
Biology, Vol 12, Iss 2, p 321 (2023)
The brain network consists of ten billion neurons and is the most complex structure in the universe. Understanding the structure of complex brain networks and neuronal functions is one of the main goals of modern neuroscience. Since the seminal inven
Externí odkaz:
https://doaj.org/article/5c40f76c5321427e8637d25a045ad785
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100166- (2020)
Summary: This protocol describes BATTLE-1EX, which is a combined method of BATTLE-1 and expansion microscopy to obtain high-resolution imaging of whole synaptic structures and their components of hippocampal neural circuits. BATTLE-1 uses two genetic
Externí odkaz:
https://doaj.org/article/b0df82f76b094fd9bb94da1a4ae8b251
Autor:
Keigo Kohara, Akitoshi Inoue, Yousuke Nakano, Hirokazu Hirai, Takuya Kobayashi, Masato Maruyama, Ryosuke Baba, Chiho Kawashima
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101248- (2020)
Summary: Elucidating fine architectures and functions of cellular and synaptic connections requires development of new flexible methods. Here, we created a concept called the “battle of transgenes,” based on which we generated strategies using ge
Externí odkaz:
https://doaj.org/article/1ab85632ee0644fba8e18c7c7513d082
Publikováno v:
STAR Protocols
STAR Protocols, Vol 1, Iss 3, Pp 100166-(2020)
STAR Protocols, Vol 1, Iss 3, Pp 100166-(2020)
Summary This protocol describes BATTLE-1EX, which is a combined method of BATTLE-1 and expansion microscopy to obtain high-resolution imaging of whole synaptic structures and their components of hippocampal neural circuits. BATTLE-1 uses two genetica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f92f957f5d2367cf8d5225edda22dc8
https://pubmed.ncbi.nlm.nih.gov/33377060
https://pubmed.ncbi.nlm.nih.gov/33377060
Autor:
Masato Maruyama, Akitoshi Inoue, Yousuke Nakano, Takuya Kobayashi, Hirokazu Hirai, Keigo Kohara, Chiho Kawashima, Ryosuke Baba
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101248-(2020)
iScience
iScience
Summary Elucidating fine architectures and functions of cellular and synaptic connections requires development of new flexible methods. Here, we created a concept called the “battle of transgenes,” based on which we generated strategies using gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5bf5eef37e65005d465e52334b2cbc1
http://www.sciencedirect.com/science/article/pii/S258900422030434X
http://www.sciencedirect.com/science/article/pii/S258900422030434X
Autor:
Junghyup Suh, Kuniya Abe, Michele Pignatelli, Susumu Tonegawa, Atsushi Yoshiki, Takashi Kitamura, Keigo Kohara
Publikováno v:
Science. 343:896-901
Entorhinal Cell Clusters There is considerable interest in understanding the function of neurons in layer 2 of the medial entorhinal cortex and how they generate their unique firing patterns, which are important in the recall of facts and past events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f84a445af17ed99611585c6bb388a245
https://doi.org/10.1126/science.1244634
https://doi.org/10.1126/science.1244634
Autor:
Dominic D. Frank, Junghyup Suh, Michele Pignatelli, Susumu Tonegawa, Ian R. Wickersham, Yuichi Obata, Keigo Kohara, Nathan Mise, Hae Yoon Jung, Alexander J. Rivest, Koichiro Kajikawa, Takashi Kitamura
Publikováno v:
Nature neuroscience
The authors use cell type–specific transgenic mouse lines, optogenetics and patch-clamp recordings to provide new insights into hippocampal anatomy and function. They find that dentate granule cells of the hippocampus, which were believed to not pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381ab7a3640651872eb120a4ed3808a5
https://doi.org/10.1038/nn.3614
https://doi.org/10.1038/nn.3614
Publikováno v:
The Journal of Neuroscience. 27:7234-7244
To address questions of whether brain-derived neurotrophic factor (BDNF) released from active excitatory neurons acts locally only on GABAergic presynaptic terminals contacting these neurons or generally also on GABAergic terminals contacting other i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e854f18a303836f93946ec1ddee3e756
https://doi.org/10.1523/jneurosci.1943-07.2007
https://doi.org/10.1523/jneurosci.1943-07.2007
Autor:
Kazuhiro Sohya, Tadaharu Tsumoto, Keigo Kohara, Mohammad Reza Palizvan, Atsushi Maruyama, Hiroki Yasuda, Fumitaka Kimura
Publikováno v:
Neuroscience. 126:955-966
To elucidate chronic actions of brain-derived neurotrophic factor (BDNF) on GABAergic synapses, we examined effects of a long-term application of BDNF for 10-15 days on autapses (synapses) of solitary GABAergic neurons cultured from rat visual cortex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ad8bf756216078c9630a55b11c9946
https://doi.org/10.1016/j.neuroscience.2004.03.053
https://doi.org/10.1016/j.neuroscience.2004.03.053
Publikováno v:
Neuroscience Research. 41:79-88
The enhancement of synaptic exocytosis is one form of long-term potentiation (LTP) of synaptic transmission. As possible mechanisms underlying this enhancement, increases in the release probability and/or the number of release sites are suggested. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0efd0f01819c2fcfe5ee7e1825e1df1b
https://doi.org/10.1016/s0168-0102(01)00267-x
https://doi.org/10.1016/s0168-0102(01)00267-x