Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Keighley N. Reisenauer"'
Autor:
Keighley N. Reisenauer, Yongfeng Tao, Provas Das, Shuxuan Song, Haleigh Svatek, Saawan D. Patel, Sheridan Mikhail, Alec Ingros, Peter Sheesley, Marco Masi, Angela Boari, Antonio Evidente, Alexander Kornienko, Daniel Romo, Joseph Taube
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The epithelial–mesenchymal transition (EMT) imparts properties of cancer stem-like cells, including resistance to frequently used chemotherapies, necessitating the identification of molecules that induce cell death specifically in stem-lik
Externí odkaz:
https://doaj.org/article/d75b28ec027d450f93ccf40375922980
Autor:
Keighley N. Reisenauer, Jaquelin Aroujo, Yongfeng Tao, Santhalakshmi Ranganathan, Daniel Romo, Joseph H. Taube
Publikováno v:
Natural Product Reports.
Residual tumor burden and chemotherapy-resistance point to a need for drug leads active toward cancer stem cells. Just as natural products have led the way for current treatments, the potential for novel applications of these molecules remains high.
Autor:
Saawan D. Patel, Shuxuan Song, Provas Das, Alec Ingros, Sheridan Mikhail, Haleigh Svatek, Angela Boari, Peter Sheesley, Antonio Evidente, Yongfeng Tao, Alexander Kornienko, Marco Masi, Daniel Romo, Joseph H. Taube, Keighley N. Reisenauer
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific reports (Nature Publishing Group) 11 (2021). doi:10.1038/s41598-021-89923-9
info:cnr-pdr/source/autori:Reisenauer K.N.; Tao Y.; Das P.; Song S.; Svatek H.; Patel S.D.; Mikhail S.; Ingros A.; Sheesley P.; Masi M.; Boari A.; Evidente A.; Kornienko A.; Romo D.; Taube J./titolo:Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A/doi:10.1038%2Fs41598-021-89923-9/rivista:Scientific reports (Nature Publishing Group)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific reports (Nature Publishing Group) 11 (2021). doi:10.1038/s41598-021-89923-9
info:cnr-pdr/source/autori:Reisenauer K.N.; Tao Y.; Das P.; Song S.; Svatek H.; Patel S.D.; Mikhail S.; Ingros A.; Sheesley P.; Masi M.; Boari A.; Evidente A.; Kornienko A.; Romo D.; Taube J./titolo:Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A/doi:10.1038%2Fs41598-021-89923-9/rivista:Scientific reports (Nature Publishing Group)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:11
The epithelial–mesenchymal transition (EMT) imparts properties of cancer stem-like cells, including resistance to frequently used chemotherapies, necessitating the identification of molecules that induce cell death specifically in stem-like cells w
Autor:
Keighley N. Reisenauer, Alec Ingros, Daniel Romo, Alexander Kornienko, Y Tao, T Philip, Joseph H. Taube, Antonio Evidente
Publikováno v:
Cancer Research. 79:P4-07
The epithelial-mesenchymal transition (EMT) enables the dissociation of cancer cells from the primary tumor by facilitating tolerance to lack of cell-adhesion, decreasing cellular division and increasing motility of individual cells, which leads to a
Autor:
Yongfeng Tao, Marco Masi, Antonio Evidente, Keighley N. Reisenauer, Joseph H. Taube, Daniel Romo
Publikováno v:
Org Lett
Pharmacophore-directed retrosynthesis applied to ophiobolin A led to bicyclic derivatives that were synthesized and display anticancer activity. Key features of the ultimate defensive synthetic strategy include a Michael addition/facially-selective p
Publikováno v:
ACS Med Chem Lett
[Image: see text] Staurosporine is among the most potent naturally occurring kinase inhibitors isolated to date and has served as a lead compound for numerous drug development efforts in several therapeutic areas. Herein we report that C–H borylati
Autor:
Daniel Romo, Alexander Kornienko, Angela Boari, Alec Ingros, Antonio Evidente, Joseph H. Taube, Shuxuan Song, Marco Masi, Saawan D. Patel, Keighley N. Reisenauer, Peter Sheesley, Yongfeng Tao
The epithelial-mesenchymal transition (EMT) imparts properties of cancer stem-like cells, including resistance to frequently used chemotherapy, necessitating the identification of molecules that induce cell death specifically in stem-like cells with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e3459163126440072106be9d5e88207
https://doi.org/10.1101/2020.05.06.079343
https://doi.org/10.1101/2020.05.06.079343
Publikováno v:
Journal of Science Communication. 21:A02
Genetics literacy is crucial for making informed decisions. However, perceived complexity, educational gaps, and misleading media narratives make reaching diverse populations difficult. Interventions to improve genetics literacy beyond K—12 classro
Autor:
Haoran Xue, Daniel Romo, Minwoo Kim, Ariane F. Bertonha, Joseph H. Taube, Alec Ingros, Joshua Robinson, Matthew Ho, Keighley N. Reisenauer, Haleigh Svatek
Publikováno v:
Tetrahedron
Concise total syntheses of (±)-7-hydroxy debromo agelastatin A (AglA), (±)-AglA, and 11-nitro AglA are presented based on an identified pseudo-symmetry element. This synthetic strategy was developed based on a desire to improve solubility of this p
Autor:
Geraldine V. Vijay, Min Gyu Lee, Tapasree Roy Sarkar, Rama Soundararajan, Jeffrey T. Chang, Neeraja Bhangre, Joon Jin Song, Taylor A. Nesbit, Keighley N. Reisenauer, Robiya Joseph, Sendurai A. Mani, Nathalie Sphyris, Kelsey S. Johnson, Joseph H. Taube
Publikováno v:
Oncotarget
// Joseph H. Taube 1, 3, 4, * , Nathalie Sphyris 1, * , Kelsey S. Johnson 3 , Keighley N. Reisenauer 3 , Taylor A. Nesbit 3 , Robiya Joseph 1 , Geraldine V. Vijay 1 , Tapasree R. Sarkar 1, 5 , Neeraja A. Bhangre 1 , Joon Jin Song 6 , Jeffrey T. Chang