Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Keifer P Walsh"'
1
Akademický článek
Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons.
Autor: Keifer P Walsh, Laurie S Minamide, Sarah J Kane, Alisa E Shaw, David R Brown, Bruce Pulford, Mark D Zabel, J David Lambeth, Thomas B Kuhn, James R Bamburg
Publikováno v: PLoS ONE, Vol 9, Iss 4, p e95995 (2014)
Neurites of neurons under acute or chronic stress form bundles of filaments (rods) containing 1∶1 cofilin∶actin, which impair transport and synaptic function. Rods contain disulfide cross-linked cofilin and are induced by treatments resulting in
Externí odkaz: https://doaj.org/article/a3df7ff5157a402b8837a2ab94fa9b44
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2
Akademický článek
A genetically encoded reporter for real-time imaging of cofilin-actin rods in living neurons.
Autor: Jianjie Mi, Alisa E Shaw, Chi W Pak, Keifer P Walsh, Laurie S Minamide, Barbara W Bernstein, Thomas B Kuhn, James R Bamburg
Publikováno v: PLoS ONE, Vol 8, Iss 12, p e83609 (2013)
Filament bundles (rods) of cofilin and actin (1:1) form in neurites of stressed neurons where they inhibit synaptic function. Live-cell imaging of rod formation is hampered by the fact that overexpression of a chimera of wild type cofilin with a fluo
Externí odkaz: https://doaj.org/article/6b6af92becf44f2bb4468f3c52a3554d
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3
Akademický článek
Chemokine Receptor Antagonists Prevent and Reverse Cofilin-Actin Rod Pathology and Protect Synapses in Cultured Rodent and Human iPSC-Derived Neurons
Autor: Thomas B. Kuhn, Laurie S. Minamide, Lubna H. Tahtamouni, Sydney A. Alderfer, Keifer P. Walsh, Alisa E. Shaw, Omar Yanouri, Henry J. Haigler, Michael R. Ruff, James R. Bamburg
Publikováno v: Biomedicines, Vol 12, Iss 1, p 93 (2024)
Synapse loss is the principal cause of cognitive decline in Alzheimer’s disease (AD) and related disorders (ADRD). Synapse development depends on the intricate dynamics of the neuronal cytoskeleton. Cofilin, the major protein regulating actin dynam
Externí odkaz: https://doaj.org/article/f60832bd48fa40ffa411a9cbf6956596
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4
Short-term outcomes after pure bone marrow aspirate injection for severe knee osteoarthritis: a case series
Autor: Javier A. Jurado Vélez, Glenn S. Fleisig, Ricardo E. Colberg, Keifer P. Walsh
Publikováno v: Regenerative Medicine. 15:1851-1859
Background: Bone marrow aspiration (BMA) is among a group of autologous cell-based therapies currently being explored to treat osteoarthritis (OA). Materials & methods: This retrospective case study observed ten patients (13 knees) with severe knee O
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efdb87f0d17518167086f2b7f369ec4f
https://doi.org/10.2217/rme-2019-0113
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5
Surgical Outcomes of Os Trigonum Syndrome in Dancers: A Case Series
Autor: Rebecca Stone McGaver, Keifer P. Walsh, J. Chris Coetzee, Elizabeth Durante, Brad R. Moser
Publikováno v: Orthopaedic Journal of Sports Medicine
Background: Management of ankle pain in dancers can be challenging because of the repetitive stress and complex demands placed on this region. Despite the prevalence of ankle injuries in this population, literature on surgical outcomes and return to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0ce4244c835db6cfcbff962fa87606
http://europepmc.org/articles/PMC7376299
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7
Cellular prion protein: A co-receptor mediating neuronal cofilin-actin rod formation induced by β-amyloid and proinflammatory cytokines
Autor: Thomas Kuhn, James R. Bamburg, Keifer P. Walsh
Increasing evidence suggests that proteins exhibiting "prion-like" behavior cause distinct neurodegenerative diseases, including inherited, sporadic and acquired types. The conversion of cellular prion protein (PrP(C)) to its infectious protease resi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0f93c1a458328b80c8b555f5e69ac4
https://europepmc.org/articles/PMC4601493/
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8
Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons
Autor: Alisa E. Shaw, David R. Brown, Laurie S. Minamide, Sarah J. Kane, Bruce Pulford, Keifer P. Walsh, J. David Lambeth, Thomas Kuhn, Mark D. Zabel, James R. Bamburg
Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e95995 (2014)
Neurites of neurons under acute or chronic stress form bundles of filaments (rods) containing 1∶1 cofilin∶actin, which impair transport and synaptic function. Rods contain disulfide cross-linked cofilin and are induced by treatments resulting in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1491403cb13b1fa025afdeb87a21aa
https://pubmed.ncbi.nlm.nih.gov/24760020
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9
A genetically encoded reporter for real-time imaging of cofilin-actin rods in living neurons
Autor: Barbara W. Bernstein, Keifer P. Walsh, Alisa E. Shaw, Chi W. Pak, James R. Bamburg, Jianjie Mi, Thomas Kuhn, Laurie S. Minamide
Publikováno v: PLoS ONE, Vol 8, Iss 12, p e83609 (2013)
PLoS ONE
Filament bundles (rods) of cofilin and actin (1:1) form in neurites of stressed neurons where they inhibit synaptic function. Live-cell imaging of rod formation is hampered by the fact that overexpression of a chimera of wild type cofilin with a fluo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a69b415f55935f8168b4ad459db2aaf
http://europepmc.org/articles/PMC3877059?pdf=render
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