Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Kei-ichiro Ishiguro"'
Autor:
Shunya Kaneko, Keita Miyoshi, Kotaro Tomuro, Makoto Terauchi, Ryoya Tanaka, Shu Kondo, Naoki Tani, Kei-Ichiro Ishiguro, Atsushi Toyoda, Azusa Kamikouchi, Hideki Noguchi, Shintaro Iwasaki, Kuniaki Saito
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Modification of guanosine to N7-methylguanosine (m7G) in the variable loop region of tRNA is catalyzed by the METTL1/WDR4 heterodimer and stabilizes target tRNA. Here, we reveal essential functions of Mettl1 in Drosophila fertility. Knockout
Externí odkaz:
https://doaj.org/article/4ec9e5921ce14741a2f17a3cab3b43ff
Autor:
Saori Yoshimura, Ryuki Shimada, Koji Kikuchi, Soichiro Kawagoe, Hironori Abe, Sakie Iisaka, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Naoki Tani, Takashi Ohba, Eiji Kondoh, Tomohide Saio, Kimi Araki, Kei-ichiro Ishiguro
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Meiotic prophase progression is differently regulated in males and females. In males, pachytene transition during meiotic prophase is accompanied by robust alteration in gene expression. However, how gene expression is regulated differently
Externí odkaz:
https://doaj.org/article/6a02458e68fa47fb9b60342236eeb4b5
Autor:
Ryuki Shimada, Yuzuru Kato, Naoki Takeda, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Hitoshi Niwa, Kimi Araki, Kei-ichiro Ishiguro
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Meiosis is differently regulated in males and females. In females, germ cells initiate meiosis within a limited time period in the fetal ovary and undergo a prolonged meiotic arrest until puberty. However, how meiosis initiation is coordinat
Externí odkaz:
https://doaj.org/article/b9127f032d2d4588b364b73be9cdf150
Autor:
Naohiro Kuwayama, Tomoya Kujirai, Yusuke Kishi, Rina Hirano, Kenta Echigoya, Lingyan Fang, Sugiko Watanabe, Mitsuyoshi Nakao, Yutaka Suzuki, Kei-ichiro Ishiguro, Hitoshi Kurumizaka, Yukiko Gotoh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Identification of factors that regulate chromatin condensation is important for understanding of gene regulation. High-mobility group AT-hook (HMGA) proteins 1 and 2 are abundant nonhistone chromatin proteins that play a role in many biologi
Externí odkaz:
https://doaj.org/article/7f8d3463872a484badc42ef07230b985
Autor:
Ryuki SHIMADA, Kei-ichiro ISHIGURO
Publikováno v:
The Journal of Reproduction and Development, Vol 69, Iss 3, Pp 139-146 (2023)
In mouse fetal gonads, germ cell development is accompanied by changes in cell cycle mode in response to external signals and intrinsic mechanisms of cells. During fetal development, male germ cells undergo G0/G1 arrest, while female germ cells exit
Externí odkaz:
https://doaj.org/article/fc2bc11e1fff4a61bbb73237bed9d8dd
Autor:
Hironori Abe, Yu-Han Yeh, Yasuhisa Munakata, Kei-Ichiro Ishiguro, Paul R. Andreassen, Satoshi H. Namekawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Here the authors show that active DNA damage response signaling is required both to initiate and maintain meiotic sex chromosome inactivation via a dynamic and reversible process.
Externí odkaz:
https://doaj.org/article/2bb2f180c2934e409411ccbe0579c7bd
Autor:
Kodai Hirano, Yuta Nonami, Yoshiaki Nakamura, Toshiyuki Sato, Takuya Sato, Kei-ichiro Ishiguro, Takehiko Ogawa, Shosei Yoshida
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
High temperatures lead to DNA double-strand break accumulation and asynapsis that trigger the meiotic checkpoint and apoptosis of spermatocytes in ex vivo cultures, providing a rationale for the heat sensitivity of sperm production in mammals.
Externí odkaz:
https://doaj.org/article/ed394f52d2104958a154c11d3fdc3dc3
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/2c979a3f6be547f3a55a46d0430eff26
Autor:
Yuki Horisawa-Takada, Chisato Kodera, Kazumasa Takemoto, Akihiko Sakashita, Kenichi Horisawa, Ryo Maeda, Ryuki Shimada, Shingo Usuki, Sayoko Fujimura, Naoki Tani, Kumi Matsuura, Tomohiko Akiyama, Atsushi Suzuki, Hitoshi Niwa, Makoto Tachibana, Takashi Ohba, Hidetaka Katabuchi, Satoshi H. Namekawa, Kimi Araki, Kei-Ichiro Ishiguro
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The authors add to our knowledge of the transcriptional regulation of the meiotic program in mice spermatocytes, showing ZFP541 regulates meiotic prophase and transition to the division phase by being the target for upstream factors MEIOSIN/STRA8.
Externí odkaz:
https://doaj.org/article/ae1c01342b7a40449dbc60cd3eaf9267
Autor:
Seiya Oura, Toshiaki Hino, Takashi Satoh, Taichi Noda, Takayuki Koyano, Ayako Isotani, Makoto Matsuyama, Shizuo Akira, Kei-Ichiro Ishiguro, Masahito Ikawa
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010241 (2022)
Meiosis is a hallmark event in germ cell development that accompanies sequential events executed by numerous molecules. Therefore, characterization of these factors is one of the best strategies to clarify the mechanism of meiosis. Here, we report tr
Externí odkaz:
https://doaj.org/article/27b9a60dbc58490cba66a515fa1e2aee