Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Kei-ichi HIRAI"'
Autor:
Eriko Simamura, Nobuaki Higashi, Kei-Ichi Hirai, Yasuhito Ishigaki, Toshihisa Hatta, Hiroki Shimada
Publikováno v:
Anatomical Science International. 83:261-266
The authors recently demonstrated that the mitochondrial voltage-dependent anion channel 1 (VDAC1) is involved in the sensitivity of cancer cells to furanonaphthoquinone (FNQ). The aim of the present study was to investigate whether mitochondrial VDA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aaa13a65fc456da8ab962964222d18b
https://doi.org/10.1111/j.1447-073x.2008.00241.x
https://doi.org/10.1111/j.1447-073x.2008.00241.x
Publikováno v:
Archives of Biochemistry and Biophysics. 402:149-157
We examined the paraquat detoxicative system in mouse livers. The survival rate of mice receiving 50 mg/kg paraquat was 41% at 7 days and significantly rose to 88, 64, 69% with pretreatment with phenytoin, phenobarbital, and rifampicin, respectively.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247f1be7a495f6064c0a62a8f38bb70c
https://doi.org/10.1016/s0003-9861(02)00059-0
https://doi.org/10.1016/s0003-9861(02)00059-0
Autor:
Jiehong Pan, Kei-Ichi Hirai, Junko Koyama, Ying-Bo Shui, Eriko Simamura, Hiroki Shimada, Toshito Kanamaru
Publikováno v:
International Journal for Vitamin and Nutrition Research. 72:147-153
The possible protection of cultured human cells from acute dioxin injury by antioxidants was investigated. The most potent dioxin, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), caused vacuolization of the smooth endoplasmic reticulum and Golgi apparatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423d8caafc65eac8f9436074c76067eb
https://doi.org/10.1024/0300-9831.72.3.147
https://doi.org/10.1024/0300-9831.72.3.147
Publikováno v:
Tissue and Cell. 33:161-168
Fate of human cancer cells damaged by mitomycin C was investigated by electron microscopy. In a monolayer culture of pulmonary adenocarcinoma A549 cells, the antitumor drug mitomycin C induced dilation of the smooth endoplasmic reticulum and Golgi ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4a016a9f1131b29279be77271b8f31
https://doi.org/10.1054/tice.2000.0167
https://doi.org/10.1054/tice.2000.0167
Publikováno v:
Phytochemistry. 53:869-872
The isolation of two cyclopentene dialdehydes, 2-formyl-5-(4'-methoxybenzoyloxy)-3-methyl-2-cyclopentene-1-acetal dehyde, and 2-formyl-5-(3', 4'-dimethoxybenzoyloxy)-3-methyl-2-cyclopentene-1-acetaldehyde, from the bark of Tabebuia impetiginosa is re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1cef96ce9aaf746fe234c65cc4421d
https://doi.org/10.1016/s0031-9422(00)00028-5
https://doi.org/10.1016/s0031-9422(00)00028-5
Publikováno v:
ACTA HISTOCHEMICA ET CYTOCHEMICA. 32:239-242
The generation of reactive oxygen species in the mitochondria was investigated using electron microscopic cytochemistry and energy-filtering transmission electron microscopy in reference to the toxic mediator of paraquat poisoning. When isolated inta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f30d3e781558c21d482ff7506fe7905
https://doi.org/10.1267/ahc.32.239
https://doi.org/10.1267/ahc.32.239
Publikováno v:
Antiviral Research. 37:37-45
Japanese encephalitis still occurs in endemic and epidemic forms over a wide area of Asia. Although the vaccine against Japanese encephalitis virus (JEV) is widely used, no antiviral drug has been reported. We used several different kinds of furanona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be49d016514ba4f2513853113e635da1
https://doi.org/10.1016/s0166-3542(97)00058-2
https://doi.org/10.1016/s0166-3542(97)00058-2
Publikováno v:
Journal of Electron Microscopy. 46:181-187
The intracellular ultrastructural changes induced by the new antitumour agent 2-methylnaphtho[2,3-b]furan-4,9-dione (FNQ3) were investigated in human cervical cancer HeLa cells in comparison with normal cervix cells. The normal cells were isolated fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0883c850de3406ee705912fd2d6c2519
https://doi.org/10.1093/oxfordjournals.jmicro.a023506
https://doi.org/10.1093/oxfordjournals.jmicro.a023506
Publikováno v:
Brain Research. 693:95-100
We tried to demonstrate the electron microscopic histochemical localization of membrane Ca2+-ATPase activity in glutaraldehyde-fixed rat sciatic nerves. Although conventional glutaraldehyde fixatives containing impurities interfered with the reactivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fee53b8ce0edf4d1cf7d98cc199bdd
https://doi.org/10.1016/0006-8993(95)00714-2
https://doi.org/10.1016/0006-8993(95)00714-2
Autor:
Kei-Ichi Hirai, Toshisuke Hiraoka
Publikováno v:
ACTA HISTOCHEMICA ET CYTOCHEMICA. 28:247-254
The platinum diaminobenzidine (Pt-DAB) reaction was characterized by the oxidative polymerization of DAB with a concurrent incorporation of Pt atoms into the polymerization product in the presence of cytochrome oxidase activity. It conformed to the M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86936622f2f07c14a120eec4a4fbac2c
https://doi.org/10.1267/ahc.28.247
https://doi.org/10.1267/ahc.28.247