Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Kei Tomihara"'
Autor:
Danki Takatsuka, Hidetake Tachinami, Nihei Suzuki, Manabu Yamazaki, Amirmoezz Yonesi, Mayu Takaichi, Shuichi Imaue, Shin-Ichi Yamada, Jun-Ichi Tanuma, Makoto Noguchi, Kei Tomihara
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumours, warranting novel treatments. Here, we examined the therapeutic efficacy of inhibiting p21 activated kinase 4 (PAK4) in OSCC and determined its immunomodulatory
Externí odkaz:
https://doaj.org/article/f41d536842d3475aa9ee82a9ac57bffa
Autor:
Ryota Kobayashi, Emi Hoshikawa, Taisuke Saito, Orakarn Suebsamarn, Eriko Naito, Ayako Suzuki, Seiichiro Ishihara, Hisashi Haga, Kei Tomihara, Kenji Izumi
Publikováno v:
FEBS Open Bio, Vol 13, Iss 8, Pp 1469-1484 (2023)
We previously reported that the cell and colony motion of oral keratinocytes are correlated with proliferative capacity, and speculated that this may be a specific index for monitoring cell quality. However, how cell motility and proliferation are re
Externí odkaz:
https://doaj.org/article/a9ae0f981e3d423386d0c6ed649b4147
Autor:
Amirmoezz Yonesi, Kei Tomihara, Danki Takatsuka, Hidetake Tachinami, Manabu Yamazaki, Amir Reza Younesi Jadidi, Mayu Takaichi, Shuichi Imaue, Kumiko Fujiwara, Shin-Ichi Yamada, Jun-Ichi Tanuma, Makoto Noguchi
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1078 (2024)
Objectives: In this study, we investigated the antitumor immunomodulatory effects of rapamycin in oral cancer. Study Design: We examined the proliferation, apoptosis, and migration of cancer cells and investigated the cell surface expression levels o
Externí odkaz:
https://doaj.org/article/ccc1f4b4f1db4f57ae22b54d8dc65aef
Autor:
Katsuhisa Sekido, Shuichi Imaue, Hidetake Tachinami, Kei Tomihara, Norihito Naruto, Kentaro Yamagishi, Atsushi Ikeda, Kumiko Fujiwara, Makoto Noguchi
Publikováno v:
Clinical Case Reports, Vol 11, Iss 12, Pp n/a-n/a (2023)
Key clinical message Nivolumab has been clinically successful in prolonging the overall survival of patients with recurrent and metastatic head and neck cancer, complete remission is rare. Synergistic combinations of immunotherapy and conventional ca
Externí odkaz:
https://doaj.org/article/21f1719b057748638c81ca0cf8df9265
Autor:
Ippei Sakamaki, Michika Fukushi, Wakana Ohashi, Yukie Tanaka, Kazuhiro Itoh, Kei Tomihara, Yoshihiro Yamamoto, Hiromichi Iwasaki
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Sepsis is a systemic reaction to an infection and resulting in excessive production of inflammatory cytokines and chemokines. It sometimes results in septic shock. The present study aimed to identify quinolone antibiotics that can reduce tum
Externí odkaz:
https://doaj.org/article/94bb97b71aaf47bc92a08143226b9860
Autor:
Muhammad Akbar, Muhammad Ruslin, Andi Sitti Hajrah Yusuf, Paolo Boffano, Kei Tomihara, Tymour Forouzanfar
Publikováno v:
Heliyon, Vol 8, Iss 9, Pp e10810- (2022)
Tetanus is an acute and vaccine-preventable disease caused by anaerobic bacteria, Clostridium tetani. This bacterium can enter the human body via a deep wound, burn injury or medical procedure; however, certain cases also originate from odontogenic i
Externí odkaz:
https://doaj.org/article/e5776b27d6c245b49078faabd18359e9
Autor:
Megumi Isshiki‐Murakami, Hidetake Tachinami, Kei Tomihara, Akira Noguchi, Katsuhisa Sekido, Shuichi Imaue, Kumiko Fujiwara, Johji Imura, Makoto Noguchi
Publikováno v:
Clinical Case Reports, Vol 9, Iss 10, Pp n/a-n/a (2021)
Abstract Intraosseous mucoepidermoid carcinoma of the jaw is a rare lesion that has been suggested to originate from the odontogenic epithelium. We report an unusual case of central mucoepidermoid carcinoma in an 18‐year‐old Japanese man with an
Externí odkaz:
https://doaj.org/article/5eb5f9e7572f45b4814f6b57c5847e6d
Autor:
Katsuhisa Sekido, Shuichi Imaue, Kei Tomihara, Hidetake Tachinami, Kentaro Yamagishi, Seisuke Okazawa, Atsushi Ikeda, Kumiko Fujiwara, Makoto Noguchi
Publikováno v:
Clinical Case Reports, Vol 9, Iss 9, Pp n/a-n/a (2021)
Abstract Although the optimal treatment method for metastatic oral cancer remains largely unknown, the present case suggests that immunotherapy is a potentially promising alternative for metastatic oral cancer in which other therapies are no longer e
Externí odkaz:
https://doaj.org/article/dcac5a75008c4ce2b5893600238b0f19
Autor:
Tatsuya Abé, Manabu Yamazaki, Satoshi Maruyama, Nobuyuki Ikeda, Yoshimasa Sumita, Kei Tomihara, Jun-ichi Tanuma
Publikováno v:
Diagnostics, Vol 12, Iss 10, p 2398 (2022)
Adenosquamous carcinoma (ASC) is an aggressive subtype of squamous cell carcinoma (SCC). Due to its poor prognosis, a precise pathological diagnosis of ASC is essential but challenging because its pathological criteria are still unclear. Here, we pre
Externí odkaz:
https://doaj.org/article/e249ff7a6f0745be902723f41fceb479
Autor:
Kohta Yamada, Takeru Hamashima, Yoko Ishii, Seiji Yamamoto, Noriko Okuno, Naofumi Yoshida, Moe Yamada, Ting Ting Huang, Norifumi Shioda, Kei Tomihara, Toshihiko Fujimori, Hisashi Mori, Kohji Fukunaga, Makoto Noguchi, Masakiyo Sasahara
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 3, Pp 1461-1479 (2018)
Background/Aims: The migration of mesenchymal cells is a fundamental cellular process that has been implicated in many pathophysiological conditions and is induced by chemoattractants such as platelet-derived growth factors (PDGFs). However, the regu
Externí odkaz:
https://doaj.org/article/3d465d4d15984092acd4962982f84de8