Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Kei Sugihara"'
Autor:
Miki Inoue, Takashi Baba, Fumiya Takahashi, Miho Terao, Shogo Yanai, Yuichi Shima, Daisuke Saito, Kei Sugihara, Takashi Miura, Shuji Takada, Mikita Suyama, Yasuyuki Ohkawa, Ken-ichirou Morohashi
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Investigation of fetal Leydig progenitors shows that thymosin β10 (Tmsb10) suppresses the RAS/ERK pathway, inducing progenitor differentiation into fetal Leydig cells.
Externí odkaz:
https://doaj.org/article/3bdd9960171d464396c4238431385530
Autor:
Yoshie Endo, Daisuke Asanuma, Shigeyuki Namiki, Kei Sugihara, Kenzo Hirose, Akiyoshi Uemura, Yoshiaki Kubota, Takashi Miura
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Microglia are resident immune cells in the central nervous system, showing a regular distribution. Advancing microscopy and image processing techniques have contributed to elucidating microglia’s morphology, dynamics, and distribution. How
Externí odkaz:
https://doaj.org/article/1fbaeb4317e04215b2358b9a286690c4
Autor:
Kei Sugihara, Yoshimi Yamaguchi, Shiori Usui, Yuji Nashimoto, Sanshiro Hanada, Etsuko Kiyokawa, Akiyoshi Uemura, Ryuji Yokokawa, Koichi Nishiyama, Takashi Miura
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240552 (2020)
A lack of perfusion has been one of the most significant obstacles for three-dimensional culture systems of organoids and embryonic tissues. Here, we developed a simple and reliable method to implement a perfusable capillary network in vitro. The met
Externí odkaz:
https://doaj.org/article/5f58b62a96c64c5a9dad79dd41e59ad2
Autor:
Kei Sugihara, Koichi Nishiyama, Shigetomo Fukuhara, Akiyoshi Uemura, Satoshi Arima, Ryo Kobayashi, Alvaro Köhn-Luque, Naoki Mochizuki, Toshio Suda, Hisao Ogawa, Hiroki Kurihara
Publikováno v:
Cell Reports, Vol 13, Iss 9, Pp 1814-1827 (2015)
Angiogenesis is a multicellular phenomenon driven by morphogenetic cell movements. We recently reported morphogenetic vascular endothelial cell (EC) behaviors to be dynamic and complex. However, the principal mechanisms orchestrating individual EC mo
Externí odkaz:
https://doaj.org/article/5a23fa822fbf48e2a6ccc74b8e538978
Autor:
Kazuya Fujimoto, Scott Erickson, Masamune Nakayama, Hiroki Ihara, Kei Sugihara, Yuji Nashimoto, Koichi Nishiyama, Takashi Miura, Ryuji Yokokawa
Publikováno v:
Lab on a Chip. 23:306-317
Blood vessel morphology is dictated by mechanical and biochemical cues. Flow-induced shear stress and pericytes both play important roles, and they have previously been studied using on-chip vascular networks to uncover their connection to angiogenic
Autor:
Shintaro Miyazaki, Tetsuhisa Otani, Kei Sugihara, Toshihiko Fujimori, Mikio Furuse, Takashi Miura
Publikováno v:
iScience. 26:106594
Publikováno v:
2022 IEEE 17th International Conference on Advanced Motion Control (AMC).
Autor:
Miki Inoue, Takashi Baba, Fumiya Takahashi, Miho Terao, Shogo Yanai, Yuichi Shima, Daisuke Saito, Kei Sugihara, Takashi Miura, Shuji Takada, Mikita Suyama, Yasuyuki Ohkawa, Ken-ichirou Morohashi
Leydig cells in fetal testes play crucial roles in masculinizing fetuses through androgen production. Gene knockout studies have revealed that growth factors are implicated in fetal Leydig cell (FLC) differentiation, but little is known about the mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::433a243653074bc2a23a8bf8451ee818
https://doi.org/10.21203/rs.3.rs-1357916/v1
https://doi.org/10.21203/rs.3.rs-1357916/v1
Autor:
Akiyoshi Uemura, Shigeyuki Namiki, Kenzo Hirose, Daisuke Asanuma, Kei Sugihara, Yoshiaki Kubota, Takashi Miura, Yoshie Endo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Microglia are resident immune cells in the central nervous system, showing a regular distribution. Advancing microscopy and image processing techniques have contributed to elucidating microglia’s morphology, dynamics, and distribution. However, the
Autor:
Tetsuhisa Otani, Takashi Miura, Taichi Sugawara, Mikio Furuse, Thanh Phuong Nguyen, Kyoko Furuse, Shinsaku Tokuda, Kei Sugihara, Klaus Ebnet
Publikováno v:
The Journal of Cell Biology
Tight junctions (TJs) are a key component of barriers formed by polarized epithelial cells. Otani et al. found that the scaffolding proteins ZO-1/ZO-2 are essential for TJ formation and epithelial polarity. Claudins regulate the TJ strand and electro