Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kei Shinoki"'
Autor:
Kinichi Hotta, Shozo Osera, Kei Shinoki, Kenichiro Imai, Sayo Ito, Yuichiro Yamaguchi, Yoshihiro Kishida, Kazunori Takada, Hiroyuki Ono
Publikováno v:
Journal of Gastroenterology and Hepatology. 37:1517-1524
Endoscopic resection of the ileocecal valve lesions (ICVL) and peri-appendiceal orifice lesions (PAOL), is challenging. This study aimed to evaluate the feasibility of endoscopic submucosal dissection (ESD) for ICVLs and PAOLs compared with other cec
Autor:
Tomoaki Shinohara, Kinichi Hotta, Yuichiro Yamaguchi, Takuma Oishi, Naomi Kakushima, Masaki Tanaka, Hiroyuki Matsubayashi, Kohei Takizawa, Hiroyuki Ono, Kenichiro Imai, Shohei Ooka, Kei Shinoki
Publikováno v:
Endoscopy. 47:529-532
Unique anatomical features render endoscopic resection for rectal tumors extending to the dentate line (RTDL) technically challenging. The aim of this study was to evaluate the feasibility of endoscopic submucosal dissection (ESD) for RTDLs.This retr
Autor:
Tetsuro Hiratsuka, Katya Gudis, Kenji Suzuki, Seiji Futagami, Kazumasa Miyake, Ken Wada, Kei Shinoki, Choitsu Sakamoto, Masanori Kusunoki, Nobue Ueki, Yoko Shinji, Taku Tsukui, Tomotaka Shindo, Tatsuhiko Hamamoto
Publikováno v:
Digestive Diseases and Sciences. 50:S84-S89
Non-steroidal anti-inflammatory drugs (NSAIDs) induced gastric mucosal injury occurs through subsequent events following free radical production derived from activated neutrophils. In this study, we hypothesized that rebamipide, a novel anti-ulcer ag
Autor:
Kazumasa Miyake, Yoko Shinji, Atsushi Tatsuguchi, Tetsuro Hiratsuka, Kenji Suzuki, Kei Shinoki, Choitsu Sakamoto, Seiji Futagami, Ken Wada, Taku Tsukui, Katya Gudis, Masafumi Kusunoki
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 288:G308-G315
We have previously shown that the cyclooxygenase (COX)-2/PGE2 pathway plays a key role in VEGF production in gastric fibroblasts. Recent studies have identified three PGE synthase (PGES) isozymes: cytosolic PGES (cPGES) and microsomal PGES (mPGES)-1
Autor:
Hitoshi Nishigaki, Kenji Suzuki, Kei Shinoki, Tetsuro Hiratsuka, Shunji Fujimori, Katya Gudis, Atsushi Tatsuguchi, Kazumasa Miyake, Seiji Futagami, Masanori Kusunoki, Yoko Shinji, Choitsu Sakamoto, Taku Tsukui, Ken Wada
Publikováno v:
Scandinavian Journal of Gastroenterology. 40:903-913
Neutrophil activation followed by free radical production is a feature that is common to the various forms of gastric injury. However, the roles of cyclooxygenase (COX)-1 and -2 in neutrophil activation have yet to be clarified in the gastric mucosa.
Autor:
Masanobu Kusunoki, Takashi Tajiri, Mikiko Tachibana, Toshiro Yoshiyuki, Seiji Futagami, Tetsuro Hiratsuka, Ken Wada, Taku Tsukui, Hitoshi Nishigaki, Kazumasa Miyake, Atsushi Tatsuguchi, Akira Tokunaga, Kei Shinoki, Choitsu Sakamoto, Yoko Shinji, Kazuhiro Nagata
Publikováno v:
Digestive Endoscopy. 16:172-175
A 52-year-old Japanese woman who presented with gastrointestinal (GI) bleeding underwent a proximal gastrectomy for a gastrointestinal stromal tumor (GIST) with a foveolar hyperplasia at the apex of the tumor, 4.5 cm in size, located in the upper bod
Autor:
Nobue Ueki, Kenji Suzuki, Tatsuhiko Hamamoto, Tetsurou Hiratsuka, Yoko Shinji, Seiji Futagami, Hitoshi Nishigaki, Kei Shinoki, Ken Wada, Taku Tsukui, Tyoitsu Sakamoto, Masafumi Kusunoki, Kazumasa Miyake
Publikováno v:
Progress of Digestive Endoscopy. 64:28-31
Autor:
Hong Lin, Taku Tsukui, Tomonori Akamatsu, Ken Wada, Kei Shinoki, Choitsu Sakamoto, Masaoki Yonezawa
Publikováno v:
Life Sciences. 73:1617-1627
The shedding mechanism for the tomoregulin (TR) ectodomain, which contains two follistatin modules and a single epidermal growth factor (EGF)-like domain, remains unclear. Our study provides the first evidence that proinflammatory cytokines, IL-1beta
Autor:
C. Sakamoto, Yoko Shinji, Masafumi Kobayashi, Kazumasa Miyake, Tetsuro Hiratsuka, Kazuhiro Nagata, Kei Shinoki, Ken Wada, Tadasu Iizumi, Taku Tsukui, Seiji Futagami, Atsushi Tatsuguchi, N. Yamada
Publikováno v:
Alimentary Pharmacology & Therapeutics. 16:210-216
Background: Helicobacter pylori eradication markedly improves histological inflammation and decreases peptic ulcer recurrence, but little is known about the subsequent development of gastric mucosal injury. Aim: To investigate whether acid suppressio
Irritant-induced cyclooxygenase-2 is involved in the defense mechanism of the gastric mucosa in mice
Autor:
Tetsuro Hiratsuka, C. Sakamoto, Kazumasa Miyake, Tadasu Iizumi, Atsushi Tatsuguchi, Masafumi Kobayashi, Kei Shinoki, Taku Tsukui, Ken Wada, Tomonori Akamatsu, Seiji Futagami
Publikováno v:
Journal of Gastroenterology. 37:164-171
Endogenous and exogenous prostaglandins (PGs) have been shown to contribute to reducing the gastric injury caused by irritants given subse-quently. The aim of this study was to clarify whether cyclooxygenase-2 (COX-2) protein induced by pretreatment