Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Kei Moriyama"'
Publikováno v:
Reports of the City Planning Institute of Japan. 21:20-23
Autor:
Shinsuke Akagi, Sayaka Fukushima, Yoichiro Takami, Kei Moriyama, Yumie Ogura, Kazunobu Takayanagi, Takehito Kamei, Mizuki Yamamoto, Ami Yakushige, Hidenori Tokuda
Publikováno v:
YAKUGAKU ZASSHI. 138:1561-1568
Hospital formulation has several advantages, including the flexibility of customization as per the disease state or the patients' precise requirements. However, compared with commercial formulations, hospital formulations are usually not under the sa
Autor:
Masafumi Kodama, Yoshiki Kishi, Tatsuro Yamamoto, Takashi Yoshio, Yuji Yada, Kazuhiro Matsuo, Shusuke Uekusa, Kei Moriyama, Kohei Kitagawa
Publikováno v:
Asian journal of psychiatry. 60
The purpose of this study was to assess the risk factors for clozapine-induced central nervous system (CNS) abnormalities (i.e., electroencephalogram [EEG] abnormalities, myoclonus, and seizures). We retrospectively analyzed data from 106 patients wi
Publikováno v:
Journal of Pharmaceutical Sciences. 107:1870-1878
The present study reports a high-throughput screening method for the salt formation of amine-containing active pharmaceutical ingredients (APIs) based on fluorescence measurements. A free form amine API was alkynylated by a solid-vapor reaction using
Autor:
Kei Moriyama
Publikováno v:
Current Pharmaceutical Design. 22:4912-4916
The importance of using the Raman imaging technique is increasing in pharmaceutical sciences, particularly in the quality control of active pharmaceutical ingredients, formulation design, and manufacturing development. Formulation design based on Ram
Autor:
Atsuko Yamamoto, Kenichi Shimada, Ayaka Nagase, Yoichiro Takami, Kei Moriyama, Takehiro Ogawa, Takae Hanada, Anna Hamahara, Yuka Inoue, Asako Kanemitsu, Takashi Egawa, Eiko Kawamoto
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 41:630-635
Publikováno v:
Journal of pharmaceutical sciences. 106(7)
Here, we report a simple and direct method to visualize the protonation/deprotonation of an amine active pharmaceutical ingredient (API) in the solid state using a solid-vapor reaction with propargyl bromide and Raman imaging for the assessment of th
Autor:
Mayumi Yamashita, Rie Yokomizo, Akiko Okuda, Kazunobu Takayanagi, Natsuki Uozumi, Kei Moriyama, Takehito Kamei, Takashi Egawa, Kenichi Shimada, Yoichiro Takami
Publikováno v:
Journal of Pharmaceutical Health Care and Sciences
Background Atropine sulfate is an anticholinergic agent for treatment of hypertrophic pyloric stenosis and is orally administrated as a triturate with lactose hydrate. Because of the low safety margin of atropine sulfate, triturate uniformity is a ke
Autor:
Tetsuya Suzuki, Kazuo Negishi, Kei Moriyama, Corinne N. Thompson, Jason D. Graci, Craig E. Cameron, Masahiko Watanabe
Publikováno v:
Journal of Medicinal Chemistry. 51:159-166
One of the possible mechanisms of antiviral action of ribavirin (1-beta- d-ribofuranosyl-1,2,4-triazole-3-carboxamide, 1) is the accumulation of mutations in viral genomic RNA. The ambiguous incorporation of 5'-triphosphate of ribavirin (RTP, 8) by a
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:5582-5585
The introduction of an unnatural base pair into DNA enables the expansion of genetic information. To apply unnatural base pairs to in vivo systems, we evaluated the cytostatic toxicity of several nucleoside analogs by an MTT assay. Several nucleoside