Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Kei Ihira"'
Autor:
Yu Miao, Yosuke Konno, Baojin Wang, Lin Zhu, Tianyue Zhai, Kei Ihira, Noriko Kobayashi, Hidemichi Watari, Xin Jin, Junming Yue, Peixin Dong, Mingyan Fang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract Background Cancer-testis antigens (CTAs) are often expressed in tumor and testicular tissues but not in other normal tissues. To date, there has been no comprehensive study of the expression and clinical significance of CTA genes associated
Externí odkaz:
https://doaj.org/article/353477f256e2443283ca73b4e8991b7b
Autor:
Peixin Dong, Ying Xiong, Yosuke Konno, Kei Ihira, Noriko Kobayashi, Junming Yue, Hidemichi Watari
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-16 (2021)
Abstract Background Epithelial-to-mesenchymal transition (EMT) and aerobic glycolysis are fundamental processes implicated in cancer metastasis. Although increasing evidence demonstrates an association between EMT induction and enhanced aerobic glyco
Externí odkaz:
https://doaj.org/article/7f6af7d5a708499e97de4f8e5907538a
Autor:
Peixin Dong, Feng Wang, Mohammad Taheri, Ying Xiong, Kei Ihira, Noriko Kobayashi, Yosuke Konno, Junming Yue, Hidemichi Watari
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Increased glycolysis in tumor cells is frequently associated with drug resistance. Overexpression of glucose transporter-1 (GLUT1) promotes the Warburg effect and mediates chemoresistance in various cancers. Aberrant GLUT1 expression is considered as
Externí odkaz:
https://doaj.org/article/6321b391970c41ae8e6c3f7bd4baf7ad
Autor:
Peixin Dong, Ying Xiong, Junming Yue, Daozhi Xu, Kei Ihira, Yosuke Konno, Noriko Kobayashi, Yukiharu Todo, Hidemichi Watari
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-15 (2019)
Abstract Background High-grade endometrioid and serous endometrial cancers (ECs) are an aggressive subtype of ECs without effective therapies. The reciprocal communication between tumor cells and their surrounding microenvironment drives tumor progre
Externí odkaz:
https://doaj.org/article/0b032b30bf354d9bb6407f1248c272f3
Autor:
Peixin Dong, Ying Xiong, Yosuke Konno, Kei Ihira, Daozhi Xu, Noriko Kobayashi, Junming Yue, Hidemichi Watari
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are a class of small non-coding RNA molecules that are 24–31 nucleotides in length. PiRNAs are thought to bind to PIWI proteins (PIWL1-4, a subfamily of Argonaute proteins), forming pi
Externí odkaz:
https://doaj.org/article/463c9f8f96ad4b5a8b7b8dab379a555b
Autor:
Daozhi Xu, Peixin Dong, Ying Xiong, Rui Chen, Yosuke Konno, Kei Ihira, Junming Yue, Hidemichi Watari
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
BackgroundPoorly differentiated endometrioid adenocarcinoma and serous adenocarcinoma represent an aggressive subtype of endometrial cancer (EC). Programmed death-ligand-1 (PD-L1) was known to exhibit a tumor cell-intrinsic function in mediating immu
Externí odkaz:
https://doaj.org/article/8234c6ce70b448a0a5e0699008dd7e7c
Autor:
Daozhi Xu, Peixin Dong, Ying Xiong, Junming Yue, Yosuke Konno, Kei Ihira, Noriko Kobayashi, Yukiharu Todo, Hidemichi Watari
Publikováno v:
Cells, Vol 9, Iss 3, p 632 (2020)
Epithelial-mesenchymal transition (EMT) is a key process contributing to cervical cancer (CC) metastasis, and microRNAs (miRNAs) modulate the expression of genes implicated in EMT. However, the accurate role of miR-361 in CC-associated EMT and the me
Externí odkaz:
https://doaj.org/article/834ca2bbb5844a2f83b7defa4cf7a1aa
Autor:
Ryuta Miyake, Hiroaki Komatsu, Kei Ihira, Akihiro Hasegawa, Yuto Maeda, Satoshi Takemori, Masashi Noguchi, Mihoko Dofutsu, Yohei Onodera, Manaka Shinagawa, Tokumasa Suemitsu, Yosuke Sugita, Yayoi Higuchi, Nanae Izaki, Chisato Kodera, Yoshikazu Nagase, Kei Odawara, Junpei Ogura, Daiken Osaku, Takuma Ohsuga, Naosuke Enomoto, Takahiro Kanai, Sakurako Mishima, Keiko Morita, Satoyo Otsuka, Kensuke Suzuki, Kiyonori Miura, Yoshio Yoshida
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 49:487-492
"Welcome to OBGYN World!" A novel recruitment event for medical students organized by the Japan Society of Obstetrics and Gynecology. Since 2012, the number of doctors in Japan who specialize in obstetrics and gynecology has shown a decreasing trend.
Autor:
Terumi Tanigawa, Nobuhiro Takeshima, Hideki Ishikawa, Shin Nishio, Tomoka Usami, Takaharu Yamawaki, Tetsuro Oishi, Kei Ihira, Hisamori Kato, Mayako Goto, Motoaki Saito, Yusuke Taira, Masatoshi Yokoyama, Tadahiro Shoji, Eiji Kondo, Atsushi Mori, Takeshi Yokoi, Naomi Iwasa-Inoue, Yasuyuki Hirashima, Takayuki Nagasawa, Motoki Takenaka, Mikio Mikami, Toru Sugiyama, Takayuki Enomoto
Publikováno v:
Gynecologic Oncology. 165:413-419
This multicenter, open-label, phase II study aimed to evaluate the efficacy and safety of paclitaxel-carboplatin, bevacizumab, and bevacizumab-based maintenance therapy for metastatic, recurrent, and persistent uterine cervical cancer.Patients with m
Autor:
Takashi Mitamura, Manami Sakurai, Hiroyuki Yamazaki, Yosuke Konno, Hidemichi Watari, Daisuke Endo, Kei Ihira
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 47:3303-3309
Aim Cytological cervical cancer screening for pregnant women is routinely performed and still plays an essential role in Japan because of the considerably low rate of human pappillomavirus (HPV) vaccination. Though almost all pregnant women undergo c